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YWHAH and KCNK15
Number of citations of the paper that reports this interaction (PMID
12433946
)
25
Data Source:
HPRD
(in vivo, two hybrid)
YWHAH
KCNK15
Gene Name
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
potassium channel, two pore domain subfamily K, member 15
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
Intercalated Disc
Cytoplasmic Vesicle Membrane
Extracellular Vesicular Exosome
Integral Component Of Membrane
Molecular Function
Actin Binding
Insulin-like Growth Factor Receptor Binding
Protein Binding
Sodium Channel Regulator Activity
Enzyme Binding
Protein Domain Specific Binding
Glucocorticoid Receptor Binding
Ion Channel Binding
Protein Heterodimerization Activity
Voltage-gated Ion Channel Activity
Potassium Channel Activity
Biological Process
Regulation Of Sodium Ion Transport
Glucocorticoid Catabolic Process
Intracellular Protein Transport
Apoptotic Process
Substantia Nigra Development
Glucocorticoid Receptor Signaling Pathway
Regulation Of Neuron Differentiation
Positive Regulation Of Transcription, DNA-templated
Regulation Of Synaptic Plasticity
Negative Regulation Of Dendrite Morphogenesis
Membrane Organization
Membrane Depolarization During Action Potential
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Regulation Of Sodium Ion Transmembrane Transporter Activity
Regulation Of Ion Transmembrane Transport
Potassium Ion Transmembrane Transport
Pathways
Activation of BAD and translocation to mitochondria
Programmed Cell Death
Translocation of GLUT4 to the plasma membrane
Activation of BH3-only proteins
Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
61 interactors:
ABL1
ARHGEF28
BAD
BCR
BRAF
CDC25B
CDC25C
CDK16
CDKN1B
CHRNA4
CREBBP
EPB41L2
EPB41L3
ESR1
ESR2
EXO1
GREM1
ING1
KCNH2
KCNK15
KCNK3
KCNK9
KIF5B
KLC3
KRT18
MAP3K3
MAP3K5
MARK4
MDM4
MED1
MST1R
NCOA1
NCOA2
NCOA3
NEK1
NR3C1
NRIP1
PARD3
PARD6A
PARD6B
PARK2
PDPK1
PRKCI
PTH1R
RAF1
REM1
RIMS1
RIMS2
RPH3A
SAMSN1
SNCA
SRC
THRA
TLX2
TNFAIP3
TPH1
TSC1
TSC2
YWHAE
YWHAG
ZFP36
7 interactors:
SFN
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
Entrez ID
7533
60598
HPRD ID
00215
09564
Ensembl ID
ENSG00000128245
Uniprot IDs
Q04917
Q9H4N8
Q9H427
PDB IDs
2C63
2C74
Enriched GO Terms of Interacting Partners
?
Signaling
Cell Communication
Regulation Of Kinase Activity
Anatomical Structure Development
Developmental Process
Cellular Response To Organic Substance
Positive Regulation Of Metabolic Process
Signal Transduction
Regulation Of Phosphorus Metabolic Process
System Development
Multicellular Organismal Development
Regulation Of Protein Phosphorylation
Cellular Response To Stimulus
Regulation Of Cell Death
Regulation Of Protein Kinase Activity
Regulation Of Cellular Process
Response To Organic Substance
Regulation Of Phosphorylation
Regulation Of Cellular Localization
Positive Regulation Of Cellular Metabolic Process
Regulation Of Signaling
Response To Stimulus
Intracellular Receptor Signaling Pathway
Regulation Of Apoptotic Process
Intracellular Steroid Hormone Receptor Signaling Pathway
Response To Hormone
Cellular Response To Hormone Stimulus
Regulation Of Signal Transduction
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Metabolic Process
Negative Regulation Of Protein Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Intracellular Signal Transduction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Negative Regulation Of Cellular Protein Metabolic Process
Regulation Of Cellular Component Organization
Regulation Of Catalytic Activity
Anatomical Structure Morphogenesis
Regulation Of Cell Proliferation
Regulation Of Metabolic Process
Negative Regulation Of Protein Phosphorylation
Organelle Organization
Cell Cycle
Negative Regulation Of Cellular Metabolic Process
Response To Organonitrogen Compound
Apoptotic Process
Cellular Response To Growth Factor Stimulus
Positive Regulation Of Programmed Cell Death
Programmed Cell Death
Response To Growth Factor
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrion Organization
Regulation Of Mitochondrion Organization
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Intracellular Transport
Apoptotic Signaling Pathway
Positive Regulation Of Organelle Organization
Regulation Of Intracellular Transport
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Regulation Of Establishment Of Protein Localization
Positive Regulation Of Transport
Regulation Of Protein Localization
Membrane Organization
Regulation Of Organelle Organization
Apoptotic Process
Programmed Cell Death
Regulation Of Cellular Localization
Cell Death
Death
Positive Regulation Of Signal Transduction
Regulation Of Apoptotic Process
Regulation Of Cell Death
Intracellular Signal Transduction
Intracellular Protein Transport
Regulation Of Cellular Component Organization
Protein Targeting
Substantia Nigra Development
Cellular Protein Localization
Protein Transport
Regulation Of Signal Transduction
Establishment Of Protein Localization
Neural Nucleus Development
Intracellular Transport
Regulation Of Signaling
Negative Regulation Of Protein Dephosphorylation
Midbrain Development
Protein Localization
Establishment Of Localization In Cell
Cellular Localization
Signal Transduction
Hippo Signaling
Negative Regulation Of Cellular Protein Metabolic Process
Signaling
Cell Communication
Negative Regulation Of Protein Metabolic Process
Tagcloud
?
3eta
3gamma
accumulates
add
bipolar
clumped
deformed
deionized
eggs
localizes
maturation
matured
meiosis
meiotic
metaphase
microinjected
microtubules
morpholino
oligonucleotide
oocyte
oocytes
proximity
reproduction
spindle
spindles
tubulin
uninjected
visualization
Tagcloud (Difference)
?
3eta
3gamma
accumulates
add
bipolar
clumped
deformed
deionized
eggs
localizes
maturation
matured
meiosis
meiotic
metaphase
microinjected
microtubules
morpholino
oligonucleotide
oocyte
oocytes
proximity
reproduction
spindle
spindles
tubulin
uninjected
visualization
Tagcloud (Intersection)
?