PCNT and CEP55

Number of citations of the paper that reports this interaction (PMID 16198290)
58

Data Source:
HPRD (in vivo)

		PCNT	CEP55
Gene Name		pericentrin	centrosomal protein 55kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Pericentriolar Material Cytoplasm Centrosome Centriole Cytosol Microtubule Membrane Motile Cilium Centriolar Satellite Ciliary Basal Body Intercellular Bridge	Centrosome Centriole Membrane Midbody Cleavage Furrow Intercellular Bridge
	Molecular Function	Protein Binding Calmodulin Binding	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Mitotic Cell Cycle In Utero Embryonic Development Neuron Migration Organelle Organization Spindle Organization Cerebellar Cortex Morphogenesis Olfactory Bulb Development Limb Morphogenesis Multicellular Organism Growth Cilium Assembly Negative Regulation Of Apoptotic Process Brain Morphogenesis Neural Precursor Cell Proliferation Positive Regulation Of Intracellular Protein Transport	Mitotic Cytokinesis Cell Separation After Cytokinesis Nucleus Organization Mitotic Metaphase Plate Congression Establishment Of Protein Localization
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: AKAP9 CALM1 CALM2 CCP110 CEP55 DISC1 PCM1 TP53BP1 TUBG1 TUBGCP2 TUBGCP3	55 interactors: AKAP9 ANXA11 ARHGEF15 C1orf109 CCBE1 CCDC53 CCHCR1 CDC45 CDK1 CDSN CEP57L1 DTNB ECSIT EIF1AD FAM90A1 FBF1 FXR2 GOLGA8DP HAUS1 HGS KIFC3 MAPK1 MAPK1IP1L MFAP1 MIA3 MORF4L2 MUM1 NOS3 PCNT PDCD6IP PEF1 PIN1 PLEKHG6 PLK1 POLM POM121 PPP1R16B PSEN2 PTPN23 RAB3D RBM17 RBM22 RCOR3 RNF32 SDCBP SNRPB SNW1 SSX2IP TCL1A TEAD4 TEX14 TFG TSG101 VPS37C VPS37D
Entrez ID		5116	55165
HPRD ID		05804	12569
Ensembl ID		ENSG00000160299	ENSG00000138180
Uniprot IDs		O95613	Q53EZ4
PDB IDs			3E1R
Enriched GO Terms of Interacting Partners?		G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Process Mitotic Cell Cycle Microtubule Cytoskeleton Organization Microtubule Nucleation Cell Cycle Process Microtubule Polymerization Microtubule-based Process Cell Cycle Organelle Organization Microtubule Polymerization Or Depolymerization Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Positive Regulation Of Transporter Activity Regulation Of Cytokinesis Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cytoskeleton Organization Regulation Of Heart Rate Positive Regulation Of Ion Transmembrane Transport Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Protein Polymerization Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Heart Contraction Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Activation Of Adenylate Cyclase Activity Nitric Oxide Metabolic Process	Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Localization Establishment Of Protein Localization Virion Assembly Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Exocytosis Protein Transport Viral Protein Processing Positive Regulation Of Transport Mitotic Cell Cycle Process Regulation Of Vesicle-mediated Transport Cell Cycle Regulation Of Exocytosis Mitotic Cell Cycle Organelle Organization Cell Division Microtubule Cytoskeleton Organization Positive Regulation Of Extracellular Vesicular Exosome Assembly Intracellular Transport Of Virus Cell Cycle Process Regulation Of Cellular Localization Viral Life Cycle Centrosome Organization Membrane Organization Cellular Localization Mitotic Nuclear Envelope Disassembly Positive Regulation Of Metabolic Process Microtubule Organizing Center Organization Regulation Of Protein Metabolic Process Regulation Of Organelle Organization Anatomical Structure Development Nuclear Envelope Disassembly G2/M Transition Of Mitotic Cell Cycle Viral Process Microtubule-based Process Viral Budding Developmental Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Anatomical Structure Morphogenesis Cell Differentiation Regulation Of Signal Transduction Cellular Response To DNA Damage Stimulus Cell Projection Morphogenesis Regulation Of Early Endosome To Late Endosome Transport Cellular Protein Localization Cell Part Morphogenesis Regulation Of Cellular Component Organization Nuclear Envelope Organization
Tagcloud ?		aberration arg585x assumed bones capabilities careful derive discreet disturbance dwarfism firm glu1774x heterozygous integrating intrauterine leu1361arg microcephaly mopd moyamoya proportionate provoke retardation segregate sga somatotropic specification suggestive syndromic underline	atad2 birc5 cdkn2a cldn6 crypt ct26 epcam flt1 g12d gp70 hif1a homozygously immunome immunotherapies mabs mhc mki67 ms4a8a ms4a8b muc2 mutated nras pbk syngeneic synonymous top2a transcriptome trp53 undifferentiated
Tagcloud (Difference) ?		aberration arg585x assumed bones capabilities careful derive discreet disturbance dwarfism firm glu1774x heterozygous integrating intrauterine leu1361arg microcephaly mopd moyamoya proportionate provoke retardation segregate sga somatotropic specification suggestive syndromic underline	atad2 birc5 cdkn2a cldn6 crypt ct26 epcam flt1 g12d gp70 hif1a homozygously immunome immunotherapies mabs mhc mki67 ms4a8a ms4a8b muc2 mutated nras pbk syngeneic synonymous top2a transcriptome trp53 undifferentiated
Tagcloud (Intersection) ?