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RPS6KB2 and RPS6
Number of citations of the paper that reports this interaction (PubMedID
16810323
)
38
Data Source:
HPRD
(in vitro)
RPS6KB2
RPS6
Description
ribosomal protein S6 kinase B2
ribosomal protein S6
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Endoplasmic Reticulum
Cytosol
Ribosome
Small Ribosomal Subunit
Membrane
Cytosolic Ribosome
Cytosolic Small Ribosomal Subunit
Dendrite
Small-subunit Processome
Cytoplasmic Ribonucleoprotein Granule
Cell Body
Presynapse
GABA-ergic Synapse
Ribonucleoprotein Complex
Molecular Function
Nucleotide Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Ribosomal Protein S6 Kinase Activity
ATP Binding
Kinase Activity
Transferase Activity
Peptide Binding
Protein Serine Kinase Activity
RNA Binding
MRNA Binding
Structural Constituent Of Ribosome
Protein Binding
Protein Kinase Binding
Biological Process
Cytoplasmic Translation
Translation
Signal Transduction
TOR Signaling
TORC1 Signaling
Positive Regulation Of Translational Initiation
Negative Regulation Of Insulin Receptor Signaling Pathway
Ribosomal Small Subunit Assembly
Cytoplasmic Translation
RRNA Processing
Translation
Positive Regulation Of Cell Population Proliferation
TOR Signaling
Response To Insulin
Ribosomal Small Subunit Biogenesis
Glucose Homeostasis
Positive Regulation Of Apoptotic Process
Cellular Response To Ethanol
Negative Regulation Of Bicellular Tight Junction Assembly
Pathways
AKT phosphorylates targets in the nucleus
Constitutive Signaling by AKT1 E17K in Cancer
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
mTORC1-mediated signalling
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
rRNA modification in the nucleus and cytosol
Major pathway of rRNA processing in the nucleolus and cytosol
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Protein hydroxylation
Response of EIF2AK4 (GCN2) to amino acid deficiency
Nuclear events stimulated by ALK signaling in cancer
SARS-CoV-1 modulates host translation machinery
SARS-CoV-2 modulates host translation machinery
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Artenimol
Diseases
GWAS
Hip circumference adjusted for BMI (
34021172
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Refractive error (
32231278
)
Waist circumference adjusted for body mass index (
34021172
)
Total cholesterol levels (
29083408
)
Interacting Genes
22 interacting genes:
BTK
CFTR
COASY
EEF2K
EP300
FBXO25
FYN
HNRNPA1
IKBKG
KAT2B
LRRK2
LYN
MAPK8IP2
MTOR
NEDD4L
PDGFRB
PDPK1
PRKCE
RPS6
SRC
SRPK1
SYK
20 interacting genes:
ATF4
DUX4
EIF4ENIF1
ERCC6
FNDC3B
FRS2
MTOR
MYOM2
NDRG1
OLFM2
PAK2
PLA2G12A
PRKACB
PRKCSH
PTEN
RPS6KB1
RPS6KB2
STAU1
UPF2
USP7
Entrez ID
6199
6194
HPRD ID
10203
01592
Ensembl ID
ENSG00000175634
ENSG00000137154
Uniprot IDs
Q9UBS0
A2A3R6
P62753
PDB IDs
4UG0
4V6X
5A2Q
5AJ0
5FLX
5LKS
5OA3
5T2C
5VYC
6F4P
6F4Q
6FEC
6G18
6G4S
6G4W
6G51
6G53
6G5H
6G5I
6IP5
6IP6
6IP8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6XA1
6Y0G
6Y2L
6Y57
6YBW
6Z6L
6Z6M
6Z6N
6ZLW
6ZM7
6ZME
6ZMI
6ZMO
6ZMT
6ZMW
6ZN5
6ZOJ
6ZOK
6ZON
6ZP4
6ZUO
6ZV6
6ZVH
6ZVJ
6ZXD
6ZXE
6ZXF
6ZXG
6ZXH
7A09
7K5I
7MQ8
7MQ9
7MQA
7QP6
7QP7
7QVP
7R4X
7TQL
7WTS
7WTT
7WTU
7WTV
7WTW
7WTX
7WTZ
7WU0
7XNX
7XNY
7ZJW
7ZJX
8G5Y
8G5Z
8G60
8G61
8G6J
8GLP
8IFD
8IFE
8JDJ
8JDK
8JDL
8JDM
8K2C
8OZ0
8PJ1
8PJ2
8PJ3
8PJ4
8PJ5
8PJ6
8PPK
8PPL
8QOI
8T4S
8UKB
8XP2
8XP3
8XSX
8XSY
8XSZ
8XXL
8XXM
8XXN
8Y0W
8Y0X
8YOO
8YOP
8ZDB
8ZDC
8ZDD
9BKD
9BLN
9C3H
9G8M
9G8O
Enriched GO Terms of Interacting Partners
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Cellular Response To Oxygen-containing Compound
Protein Phosphorylation
Kinase Activity
Protein Kinase Activity
Phosphorylation
Transferase Activity
Positive Regulation Of Cellular Component Organization
Protein Modification Process
Phospholipase Binding
Peptidyl-tyrosine Phosphorylation
Stimulatory C-type Lectin Receptor Signaling Pathway
Cellular Response To Lectin
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc Receptor Signaling Pathway
ATP Binding
Fc Receptor Mediated Stimulatory Signaling Pathway
Positive Regulation Of Intracellular Signal Transduction
Protein Tyrosine Kinase Activity
Innate Immune Response Activating Cell Surface Receptor Signaling Pathway
Cellular Response To Stress
Immune Response-activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cell Activation
Fc-gamma Receptor Signaling Pathway
Phospholipase Activator Activity
Protein Metabolic Process
Phosphate-containing Compound Metabolic Process
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Nucleotide Binding
Response To Hormone
Regulation Of Innate Immune Response
Innate Immune Response-activating Signaling Pathway
Non-membrane Spanning Protein Tyrosine Kinase Activity
Intracellular Signal Transduction
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Response To Peptide Hormone
T Cell Costimulation
Cytoplasm
Response To Stress
Activation Of Innate Immune Response
Positive Regulation Of Lymphocyte Activation
Regulation Of Transport
Immune Response-activating Signaling Pathway
Protein Autophosphorylation
Positive Regulation Of Signal Transduction
Regulation Of Vesicle-mediated Transport
Positive Regulation Of Immune System Process
Regulation Of Cellular Component Organization
Transmembrane Transporter Binding
Cellular Response To Nutrient Levels
TORC1 Signaling
TOR Signaling
Cellular Response To Nutrient Levels
Intracellular Signal Transduction
Negative Regulation Of TORC1 Signaling
Regulation Of Protein Metabolic Process
Negative Regulation Of TOR Signaling
Regulation Of TORC1 Signaling
Regulation Of Translational Initiation
Cytoplasm
Positive Regulation Of Transcription By RNA Polymerase I
PML Body
Negative Regulation Of TORC2 Signaling
Response To Nutrient Levels
Regulation Of Transcription By RNA Polymerase I
Positive Regulation Of Translational Initiation
Negative Regulation Of Insulin Receptor Signaling Pathway
Negative Regulation Of Cellular Response To Insulin Stimulus
Regulation Of TOR Signaling
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Protein Metabolic Process
Protein Serine Kinase Activity
Negative Regulation Of Cell Size
Vascular Endothelial Cell Response To Laminar Fluid Shear Stress
Protein Serine/threonine Kinase Activity
Regulation Of Insulin Receptor Signaling Pathway
Transcription-coupled Nucleotide-excision Repair
Cellular Response To Leucine Starvation
Regulation Of Translation
Regulation Of Cellular Response To Insulin Stimulus
Regulation Of TORC2 Signaling
Cytoplasmic Ribonucleoprotein Granule
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
TORC2 Signaling
Vascular Endothelial Cell Response To Fluid Shear Stress
Myelin Maintenance
Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Protein Tyrosine Kinase Activator Activity
Signal Transduction
Negative Regulation Of Intracellular Signal Transduction
Positive Regulation Of Transcription By RNA Polymerase III
Autophagosome Assembly
Cellular Response To Laminar Fluid Shear Stress
Cellular Response To Stress
Autophagosome Organization
Protein Kinase Activity
Negative Regulation Of Autophagy
Response To Laminar Fluid Shear Stress
Positive Regulation Of Catabolic Process
Cytoplasmic Translation
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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