FKBP3 and FBXO25

Number of citations of the paper that reports this interaction (PMID 23940030)
0

Data Source:
BioGRID (enzymatic study)

		FKBP3	FBXO25
Gene Name		FK506 binding protein 3, 25kDa	F-box protein 25
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Membrane	Ubiquitin Ligase Complex Nucleus Nucleolus SCF Ubiquitin Ligase Complex
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Receptor Activity Protein Binding FK506 Binding Poly(A) RNA Binding	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Chaperone-mediated Protein Folding	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: BARD1 CALM1 CSNK2A1 CSNK2A2 CSNK2B FBXO25 HDAC1 HDAC2 MTA2 NEDD4 NEDD4L SRPK1 YY1	80 interactors: ADRBK1 ANKRD13A APLF AXL BMX C11orf63 C19orf57 C6orf106 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ING3 IRS1 KDR KRT8 LMCD1 LUC7L MAT2B NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1
Entrez ID		2287	26260
HPRD ID		01743	16439
Ensembl ID		ENSG00000100442	ENSG00000147364
Uniprot IDs		Q00688	Q8TCJ0
PDB IDs		1PBK 2KFV
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Cell Cycle Histone Deacetylation Regulation Of Protein Metabolic Process Protein Deacetylation Positive Regulation Of Protein Catabolic Process Regulation Of Cell Cycle Protein Metabolic Process ATP-dependent Chromatin Remodeling Fungiform Papilla Formation Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Fungiform Papilla Morphogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Receptor Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Fungiform Papilla Development Negative Regulation Of Sodium Ion Transport Cellular Response To Light Stimulus Cellular Metabolic Process Eyelid Development In Camera-type Eye Negative Regulation Of Ion Transport Regulation Of Gene Expression Hair Follicle Placode Formation Tongue Morphogenesis Cellular Response To Stimulus Regulation Of Receptor Biosynthetic Process Negative Regulation Of Biosynthetic Process Histone H4 Deacetylation Negative Regulation Of Transport Neuron Projection Development Cellular Response To Radiation Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Cell Surface Receptor Signaling Pathway Nitrogen Compound Metabolic Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Potassium Ion Transmembrane Transporter Activity Protein Polyubiquitination Neuron Development Anatomical Structure Morphogenesis	Regulation Of Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Peptidyl-amino Acid Modification Cellular Metabolic Process Cellular Protein Modification Process Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Response To Stress Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Innate Immune Response Neurotrophin Signaling Pathway Viral Process Protein Phosphorylation Cellular Response To Stimulus Cellular Response To Growth Factor Stimulus Fibroblast Growth Factor Receptor Signaling Pathway Cellular Protein Metabolic Process Response To Growth Factor Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Gene Expression Peptidyl-tyrosine Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of Phospholipase C Activity Phosphorylation Intracellular Signal Transduction Regulation Of Cellular Process Rhythmic Process Protein Autophosphorylation Positive Regulation Of Phospholipase Activity Response To Stimulus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Organic Substance Immune Response Proteasomal Protein Catabolic Process G1/S Transition Of Mitotic Cell Cycle Response To UV-A Peptidyl-serine Autophosphorylation Regulation Of Phospholipase Activity Apoptotic Process Positive Regulation Of Lipase Activity Defense Response Protein Metabolic Process Regulation Of Cell Death Immune System Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process
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