Wiki-Pi
About
Search
People
Updates
Search
TXNIP and KPNA2
Number of citations of the paper that reports this interaction (PubMedID
15234975
)
0
Data Source:
HPRD
(two hybrid, in vitro)
TXNIP
KPNA2
Description
thioredoxin interacting protein
karyopherin subunit alpha 2
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Golgi Membrane
Nucleus
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Golgi Apparatus
Cytosol
Membrane
Nuclear Membrane
NLS-dependent Protein Nuclear Import Complex
Host Cell
Molecular Function
Enzyme Inhibitor Activity
Protein Binding
Ubiquitin Protein Ligase Binding
RNA Binding
Protein Binding
Nuclear Localization Sequence Binding
Histone Deacetylase Binding
Nuclear Import Signal Receptor Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Protein Import Into Nucleus
Inflammatory Response
Response To Oxidative Stress
Response To Xenobiotic Stimulus
Response To Mechanical Stimulus
Response To Glucose
Protein Transport
Keratinocyte Differentiation
Response To Estradiol
Response To Progesterone
Regulation Of Cell Population Proliferation
Response To Hydrogen Peroxide
Positive Regulation Of Apoptotic Process
Platelet-derived Growth Factor Receptor Signaling Pathway
Response To Calcium Ion
Negative Regulation Of Cell Division
Cellular Response To Tumor Cell
Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus
Regulation Of DNA Recombination
DNA Metabolic Process
Protein Import Into Nucleus
NLS-bearing Protein Import Into Nucleus
Protein Transport
Positive Regulation Of Type I Interferon Production
Non-canonical NF-kappaB Signal Transduction
Positive Regulation Of DNA-templated Transcription
Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin
Positive Regulation Of Viral Life Cycle
Pathways
The NLRP3 inflammasome
The NLRP3 inflammasome
Regulation of FOXO transcriptional activity by acetylation
Purinergic signaling in leishmaniasis infection
Purinergic signaling in leishmaniasis infection
Cytoprotection by HMOX1
CaMK IV-mediated phosphorylation of CREB
ISG15 antiviral mechanism
NS1 Mediated Effects on Host Pathways
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde
Sensing of DNA Double Strand Breaks
Estrogen-dependent gene expression
SARS-CoV-1 activates/modulates innate immune responses
SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Feeling lonely (
29500382
)
General risk tolerance (MTAG) (
30643258
)
Loneliness (
29970889
)
Loneliness (MTAG) (
29970889
)
Refractive error (
32231278
)
Regular attendance at a religious group (
29970889
)
Interacting Genes
30 interacting genes:
CBX8
DDIT4
ECD
EEF1A1
FHL1
GAPDH
HDAC1
HDAC3
HSPB2
IDI1
INTS9
KPNA2
LUC7L3
MAPK1
NLGN3
PRKAA1
PTPN11
RUVBL2
SCEL
SIVA1
SLC2A1
SMURF2
TRAF6
TXN
TXNRD1
UBR5
UXT
WWP1
ZBTB16
ZBTB32
111 interacting genes:
ACTN1
ACTN4
ANKIB1
AP2B1
APOBEC1
APP
ARL4A
ARL5A
ATXN3
BAG6
BRCA1
BTBD2
CASP2
CCDC107
CDA
CDC42
CDK5RAP3
CHD3
CHEK2
CORO1B
CREB3L3
CREBBP
CSNK1A1
CUL4B
DCPS
DCTN2
DDIT3
EIF4ENIF1
EP300
EPB41
FEZ2
FN1
FTH1
GART
GMCL1
GRB2
GTF2IRD1
H1-0
HAP1
HMG20A
HNRNPC
HOMER2
HOMEZ
HSPA4
IFT20
IMMT
INO80E
ITK
JUN
KLC4
KPNB1
KRT18
KRT40
KRT8
LAMB2
LEF1
LZTS2
MAGED1
MAGEH1
MDFI
MLH1
MORC3
MORF4L1
MVP
NECAB2
NFE2L2
NFKBIB
NMNAT1
NR3C1
NUP153
NUP50
NUP62
NUTM1
OGT
PAX5
PLAG1
PNMA5
PRKD3
PTMA
RAG1
RANBP2
RBM48
RBPMS
RECQL
RELA
RELB
RGL2
RILP
RNMT
SERTAD3
SGK1
SLC2A2
SPRY1
SRPK1
STUB1
SUMO2
TADA2A
TAF3
TAF8
TANK
TBPL2
TP53
TRAF1
TRIM54
TSC22D4
TXNIP
UBR5
USHBP1
ZBTB7B
ZC3H12A
ZNF131
Entrez ID
10628
3838
HPRD ID
05964
02818
Ensembl ID
ENSG00000265972
ENSG00000182481
Uniprot IDs
Q9H3M7
P52292
PDB IDs
4GEI
4GEJ
4GFX
4LL1
4LL4
4ROF
4ROJ
5CQ2
5DF6
5DWS
5DZD
1EFX
1QGK
1QGR
3FEX
3FEY
3WPT
4E4V
4WV6
5H43
7CRU
7N8J
7N9H
8FZK
8GCN
Enriched GO Terms of Interacting Partners
?
Nucleus
Cytosol
Cytoplasm
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Protein Lysine Delactylase Activity
Regulation Of Signal Transduction
Positive Regulation Of Type I Interferon Production
Negative Regulation Of Metabolic Process
Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Metabolic Process
Nucleoplasm
Protein Decrotonylase Activity
Histone Decrotonylase Activity
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Protein Export From Nucleus
Regulation Of Protein Stability
Regulation Of Gene Expression
Positive Regulation Of Signal Transduction
Protein Modification Process
Regulation Of Cell Communication
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Signaling
Regulation Of RNA Metabolic Process
Regulation Of Nucleocytoplasmic Transport
Thioredoxin-disulfide Reductase (NADPH) Activity
Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Primary Metabolic Process
Regulation Of Type I Interferon Production
Histone Deacetylase Binding
Negative Regulation Of Protein Export From Nucleus
Transcription Corepressor Binding
Regulation Of Metabolic Process
Negative Regulation Of Signal Transduction
Regulation Of Macromolecule Metabolic Process
Regulation Of Intracellular Transport
Response To Epidermal Growth Factor
Regulation Of Intracellular Protein Transport
Histone Deacetylase Activity, Hydrolytic Mechanism
Bergmann Glial Cell Differentiation
Nucleus
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Metabolic Process
Regulation Of Primary Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Metabolic Process
Regulation Of Metabolic Process
Identical Protein Binding
Regulation Of RNA Metabolic Process
Nucleoplasm
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of RNA Metabolic Process
Chromatin Organization
Regulation Of Programmed Cell Death
Negative Regulation Of Transcription By RNA Polymerase II
Ubiquitin Protein Ligase Binding
Intracellular Signal Transduction
DNA Damage Response
Cytoplasm
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Regulation Of Apoptotic Process
Regulation Of Signal Transduction
Negative Regulation Of Biosynthetic Process
Cytosol
Positive Regulation Of Response To Endoplasmic Reticulum Stress
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Transcription By RNA Polymerase II
Protein-containing Complex
Protein Binding
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Nuclear Inclusion Body
Positive Regulation Of Proteolysis
Regulation Of Protein Catabolic Process
Negative Regulation Of Catabolic Process
Regulation Of Transcription By RNA Polymerase II
Protein Import Into Nucleus
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?