KPNA2 and ZNF131

Number of citations of the paper that reports this interaction (PMID 17306895)
3

Data Source:
BioGRID (pull down)

		KPNA2	ZNF131
Gene Name		karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	zinc finger protein 131
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Membrane	Nucleus
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Protein Transporter Activity Histone Deacetylase Binding Poly(A) RNA Binding	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding
	Biological Process	Regulation Of DNA Recombination DNA Metabolic Process NLS-bearing Protein Import Into Nucleus Viral Process Cytokine-mediated Signaling Pathway	Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter
Pathways		ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS
Protein-Protein Interactions		104 interactors: ACTN1 ACTN4 ANKIB1 AP2B1 APOBEC1 APP ARL4A ARL5A BRCA1 BTBD2 CASP2 CCDC107 CDA CDK5RAP3 CHD3 CHEK2 CORO1B CREB3L3 CREBBP CSE1L CSNK1A1 CUL4B DCTN2 DDIT3 EP300 EPB41 FEZ2 FN1 FTH1 GART GMCL1 GRB2 H1F0 HAP1 HMG20A HNRNPC HOMER2 HOMEZ HSPA4 IFT20 IMMT INO80E ITK JUN KLC4 KPNB1 KRT18 KRT40 KRT8 LAMB2 LEF1 LZTS2 MAGED1 MAGEH1 MDFI MLH1 MORC3 MVP MYC NECAB2 NFKBIB NMNAT1 NR3C1 NUP153 NUP50 NUP62 NUTM1 PAX5 PLAG1 PNMA5 PRKD3 PTMA RAG1 RAN RANBP2 RBM48 RBPMS RECQL RELA RELB RGL2 RILP RNMT SART3 SERTAD3 SGK1 SLC2A2 SPRY1 SRPK1 TADA2A TAF3 TAF8 TANK TBPL2 TP53 TRAF1 TRIM54 TSC22D4 TXNIP UBR5 USHBP1 ZBTB7B ZC3H12A ZNF131	4 interactors: FHL2 KPNA2 KPNA3 KPNA6
Entrez ID		3838	7690
HPRD ID		02818	07239
Ensembl ID		ENSG00000182481	ENSG00000172262
Uniprot IDs		P52292 Q7Z726	P52739
PDB IDs		1EFX 1QGK 1QGR 3FEX 3FEY 4E4V
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Cellular Process RNA Biosynthetic Process Gene Expression Response To Stimulus Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Cell Death Death Apoptotic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process Programmed Cell Death Viral Process Organelle Organization Regulation Of Nucleic Acid-templated Transcription Signal Transduction Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Developmental Process Regulation Of Transcription, DNA-templated Signaling Positive Regulation Of Transcription, DNA-templated Protein Localization To Nucleus Macromolecule Biosynthetic Process Cellular Localization Cell Cycle Negative Regulation Of Biosynthetic Process Cell Communication Negative Regulation Of Nucleic Acid-templated Transcription Cellular Process Negative Regulation Of RNA Biosynthetic Process Cell Cycle Process Response To Stress Positive Regulation Of Gene Expression Nucleocytoplasmic Transport Negative Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Response To Abiotic Stimulus Negative Regulation Of Transcription, DNA-templated Nuclear Transport Positive Regulation Of Macromolecule Biosynthetic Process Multicellular Organismal Development	NLS-bearing Protein Import Into Nucleus Protein Import Into Nucleus Nuclear Import Protein Import Protein Localization To Nucleus Nucleocytoplasmic Transport Nuclear Transport Establishment Of Protein Localization To Organelle Protein Targeting Protein Localization To Organelle Cytoplasmic Transport Intracellular Protein Transport Viral Penetration Into Host Nucleus Atrial Cardiac Muscle Cell Development Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Cytokine-mediated Signaling Pathway Establishment Of Localization In Cell Heart Trabecula Formation Viral Process Ventricular Cardiac Muscle Cell Development Cellular Response To Cytokine Stimulus Cellular Localization Response To Organic Substance Heart Trabecula Morphogenesis Intracellular Transport Of Virus Ventricular Cardiac Muscle Cell Differentiation Response To Cytokine Androgen Receptor Signaling Pathway Viral Entry Into Host Cell Entry Into Host Cell Trabecula Morphogenesis Regulation Of DNA Recombination Cardiac Muscle Cell Development Intracellular Steroid Hormone Receptor Signaling Pathway Maternal Process Involved In Female Pregnancy Positive Regulation Of Transcription, DNA-templated Interaction With Host Cardiac Muscle Cell Differentiation
Tagcloud ?		aggressive aggressiveness assembled attempt carcinomas curable diagnostics disregarding eic emgd endometrial entities figo immunoreactivity interplay introducing malignancy mediator mfe microarrays nucleocytoplasmic precancerous regimens surgically tmas trp53 tumour untreatable uterus	11p15 19q13 1p36 20p11 3q21 7q11 7q21 alagille beckwith chromosomally deleted gli krab kruppel q22 shfd1 split straightforward wiedemann williams znf148 znfs
Tagcloud (Difference) ?		aggressive aggressiveness assembled attempt carcinomas curable diagnostics disregarding eic emgd endometrial entities figo immunoreactivity interplay introducing malignancy mediator mfe microarrays nucleocytoplasmic precancerous regimens surgically tmas trp53 tumour untreatable uterus	11p15 19q13 1p36 20p11 3q21 7q11 7q21 alagille beckwith chromosomally deleted gli krab kruppel q22 shfd1 split straightforward wiedemann williams znf148 znfs
Tagcloud (Intersection) ?