KPNA2 and RILP

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		KPNA2	RILP
Gene Name		karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	Rab interacting lysosomal protein
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Membrane	Mitochondrion Lysosome Lysosomal Membrane Late Endosome Phagocytic Vesicle Membrane Late Endosome Membrane Protein Complex
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Protein Transporter Activity Histone Deacetylase Binding Poly(A) RNA Binding	Protein Binding Rab GTPase Binding
	Biological Process	Regulation Of DNA Recombination DNA Metabolic Process NLS-bearing Protein Import Into Nucleus Viral Process Cytokine-mediated Signaling Pathway	Endosome To Lysosome Transport Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways		ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes	MHC class II antigen presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		104 interactors: ACTN1 ACTN4 ANKIB1 AP2B1 APOBEC1 APP ARL4A ARL5A BRCA1 BTBD2 CASP2 CCDC107 CDA CDK5RAP3 CHD3 CHEK2 CORO1B CREB3L3 CREBBP CSE1L CSNK1A1 CUL4B DCTN2 DDIT3 EP300 EPB41 FEZ2 FN1 FTH1 GART GMCL1 GRB2 H1F0 HAP1 HMG20A HNRNPC HOMER2 HOMEZ HSPA4 IFT20 IMMT INO80E ITK JUN KLC4 KPNB1 KRT18 KRT40 KRT8 LAMB2 LEF1 LZTS2 MAGED1 MAGEH1 MDFI MLH1 MORC3 MVP MYC NECAB2 NFKBIB NMNAT1 NR3C1 NUP153 NUP50 NUP62 NUTM1 PAX5 PLAG1 PNMA5 PRKD3 PTMA RAG1 RAN RANBP2 RBM48 RBPMS RECQL RELA RELB RGL2 RILP RNMT SART3 SERTAD3 SGK1 SLC2A2 SPRY1 SRPK1 TADA2A TAF3 TAF8 TANK TBPL2 TP53 TRAF1 TRIM54 TSC22D4 TXNIP UBR5 USHBP1 ZBTB7B ZC3H12A ZNF131	7 interactors: KPNA2 LDB2 RAB34 RAB7A RCHY1 SNF8 VPS36
Entrez ID		3838	83547
HPRD ID		02818	09706
Ensembl ID		ENSG00000182481	ENSG00000167705
Uniprot IDs		P52292 Q7Z726	Q96NA2
PDB IDs		1EFX 1QGK 1QGR 3FEX 3FEY 4E4V	1YHN
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Cellular Process RNA Biosynthetic Process Gene Expression Response To Stimulus Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Cell Death Death Apoptotic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process Programmed Cell Death Viral Process Organelle Organization Regulation Of Nucleic Acid-templated Transcription Signal Transduction Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Developmental Process Regulation Of Transcription, DNA-templated Signaling Positive Regulation Of Transcription, DNA-templated Protein Localization To Nucleus Macromolecule Biosynthetic Process Cellular Localization Cell Cycle Negative Regulation Of Biosynthetic Process Cell Communication Negative Regulation Of Nucleic Acid-templated Transcription Cellular Process Negative Regulation Of RNA Biosynthetic Process Cell Cycle Process Response To Stress Positive Regulation Of Gene Expression Nucleocytoplasmic Transport Negative Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Response To Abiotic Stimulus Negative Regulation Of Transcription, DNA-templated Nuclear Transport Positive Regulation Of Macromolecule Biosynthetic Process Multicellular Organismal Development	Phagosome-lysosome Fusion Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Phagolysosome Assembly Protein Transport Establishment Of Protein Localization Protein Targeting To Vacuole Intracellular Transport Endosomal Transport Establishment Of Protein Localization To Vacuole Cytoplasmic Transport Membrane Organization Protein Localization Intracellular Protein Transport Phagosome Maturation Establishment Of Localization In Cell Vesicle Fusion Establishment Of Protein Localization To Organelle Lysosome Organization Rab Protein Signal Transduction Positive Regulation Of Exocytosis Protein Targeting Cellular Localization Organelle Fusion Vacuolar Transport Epidermal Growth Factor Catabolic Process Cellular Protein Localization Protein Localization To Organelle Vacuole Organization Cellular Protein Catabolic Process Protein Catabolic Process Membrane Fusion Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Exocytosis Tissue Homeostasis Phagosome Acidification Cellular Macromolecule Catabolic Process Vesicle Organization Endosome Transport Via Multivesicular Body Sorting Pathway Ras Protein Signal Transduction Late Endosome To Vacuole Transport Multicellular Organismal Homeostasis Protein To Membrane Docking Phagocytosis Nucleocytoplasmic Transport Nuclear Transport Antigen Processing And Presentation Protein Targeting To Lysosome Positive Regulation Of Secretion Protein Localization To Lysosome
Tagcloud ?		aggressive aggressiveness assembled attempt carcinomas curable diagnostics disregarding eic emgd endometrial entities figo immunoreactivity interplay introducing malignancy mediator mfe microarrays nucleocytoplasmic precancerous regimens surgically tmas trp53 tumour untreatable uterus	anterograde arborization blunts brake branching dendrite dendrites dendritic frontotemporal interacting knockdown live lobar localizes lysosomal lysosomes map6 misrouting neurodegeneration presumably prevents rab7 rescues restores retrograde strengthen tmem106b trafficking transport
Tagcloud (Difference) ?		aggressive aggressiveness assembled attempt carcinomas curable diagnostics disregarding eic emgd endometrial entities figo immunoreactivity interplay introducing malignancy mediator mfe microarrays nucleocytoplasmic precancerous regimens surgically tmas trp53 tumour untreatable uterus	anterograde arborization blunts brake branching dendrite dendrites dendritic frontotemporal interacting knockdown live lobar localizes lysosomal lysosomes map6 misrouting neurodegeneration presumably prevents rab7 rescues restores retrograde strengthen tmem106b trafficking transport
Tagcloud (Intersection) ?