KPNA2 and TAF3

Number of citations of the paper that reports this interaction (PMID 15870280)
9

Data Source:
BioGRID (pull down)

		KPNA2	TAF3
Gene Name		karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Membrane	Nucleus Nucleoplasm Transcription Factor TFIID Complex
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Protein Transporter Activity Histone Deacetylase Binding Poly(A) RNA Binding	P53 Binding Protein Binding Zinc Ion Binding
	Biological Process	Regulation Of DNA Recombination DNA Metabolic Process NLS-bearing Protein Import Into Nucleus Viral Process Cytokine-mediated Signaling Pathway	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Maintenance Of Protein Location In Nucleus
Pathways		ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes	RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS
Protein-Protein Interactions		104 interactors: ACTN1 ACTN4 ANKIB1 AP2B1 APOBEC1 APP ARL4A ARL5A BRCA1 BTBD2 CASP2 CCDC107 CDA CDK5RAP3 CHD3 CHEK2 CORO1B CREB3L3 CREBBP CSE1L CSNK1A1 CUL4B DCTN2 DDIT3 EP300 EPB41 FEZ2 FN1 FTH1 GART GMCL1 GRB2 H1F0 HAP1 HMG20A HNRNPC HOMER2 HOMEZ HSPA4 IFT20 IMMT INO80E ITK JUN KLC4 KPNB1 KRT18 KRT40 KRT8 LAMB2 LEF1 LZTS2 MAGED1 MAGEH1 MDFI MLH1 MORC3 MVP MYC NECAB2 NFKBIB NMNAT1 NR3C1 NUP153 NUP50 NUP62 NUTM1 PAX5 PLAG1 PNMA5 PRKD3 PTMA RAG1 RAN RANBP2 RBM48 RBPMS RECQL RELA RELB RGL2 RILP RNMT SART3 SERTAD3 SGK1 SLC2A2 SPRY1 SRPK1 TADA2A TAF3 TAF8 TANK TBPL2 TP53 TRAF1 TRIM54 TSC22D4 TXNIP UBR5 USHBP1 ZBTB7B ZC3H12A ZNF131	4 interactors: HIST3H3 KPNA2 KPNB1 TAF10
Entrez ID		3838	83860
HPRD ID		02818	19377
Ensembl ID		ENSG00000182481
Uniprot IDs		P52292 Q7Z726	Q5VWG9
PDB IDs		1EFX 1QGK 1QGR 3FEX 3FEY 4E4V
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Cellular Process RNA Biosynthetic Process Gene Expression Response To Stimulus Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Cell Death Death Apoptotic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process Programmed Cell Death Viral Process Organelle Organization Regulation Of Nucleic Acid-templated Transcription Signal Transduction Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Developmental Process Regulation Of Transcription, DNA-templated Signaling Positive Regulation Of Transcription, DNA-templated Protein Localization To Nucleus Macromolecule Biosynthetic Process Cellular Localization Cell Cycle Negative Regulation Of Biosynthetic Process Cell Communication Negative Regulation Of Nucleic Acid-templated Transcription Cellular Process Negative Regulation Of RNA Biosynthetic Process Cell Cycle Process Response To Stress Positive Regulation Of Gene Expression Nucleocytoplasmic Transport Negative Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Response To Abiotic Stimulus Negative Regulation Of Transcription, DNA-templated Nuclear Transport Positive Regulation Of Macromolecule Biosynthetic Process Multicellular Organismal Development	NLS-bearing Protein Import Into Nucleus Viral Process Protein Import Into Nucleus Nuclear Import Protein Import Protein Localization To Nucleus DNA Metabolic Process Nucleocytoplasmic Transport Nuclear Transport Ribosomal Protein Import Into Nucleus Establishment Of Protein Localization To Organelle Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Protein Targeting Cellular Nitrogen Compound Metabolic Process Cytokine-mediated Signaling Pathway Protein Localization To Organelle Nitrogen Compound Metabolic Process Apoptotic DNA Fragmentation Histone Deubiquitination Cellular Response To Cytokine Stimulus Intracellular Transport Of Virus Cytoplasmic Transport Protein Import Into Nucleus, Translocation Apoptotic Nuclear Changes Response To Cytokine Histone H3 Acetylation Intracellular Protein Transport Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Transcription Elongation From RNA Polymerase II Promoter Chromosome Organization Regulation Of DNA Recombination Execution Phase Of Apoptosis Telomere Maintenance DNA-templated Transcription, Elongation DNA Catabolic Process, Endonucleolytic Cellular Protein Localization Protein Deubiquitination Histone Acetylation Protein Transport Internal Peptidyl-lysine Acetylation Protein Modification By Small Protein Removal Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Establishment Of Protein Localization Protein Acetylation Intracellular Transport
Tagcloud ?		aggressive aggressiveness assembled attempt carcinomas curable diagnostics disregarding eic emgd endometrial entities figo immunoreactivity interplay introducing malignancy mediator mfe microarrays nucleocytoplasmic precancerous regimens surgically tmas trp53 tumour untreatable uterus	assembly box cooperatively direct directs effector enhances genotoxic global h3k4me3 include independently interactions mark modifications p53 pic preinitiation prominent promotes rapid recruitment regulate remain stimulating tata tfiid unclear yet
Tagcloud (Difference) ?		aggressive aggressiveness assembled attempt carcinomas curable diagnostics disregarding eic emgd endometrial entities figo immunoreactivity interplay introducing malignancy mediator mfe microarrays nucleocytoplasmic precancerous regimens surgically tmas trp53 tumour untreatable uterus	assembly box cooperatively direct directs effector enhances genotoxic global h3k4me3 include independently interactions mark modifications p53 pic preinitiation prominent promotes rapid recruitment regulate remain stimulating tata tfiid unclear yet
Tagcloud (Intersection) ?