KPNA2 and IFT20

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		KPNA2	IFT20
Gene Name		karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	intraflagellar transport 20
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Membrane	Golgi Membrane Photoreceptor Outer Segment Golgi Apparatus Centrosome Centriole Cilium Microtubule Cytoskeleton Intraciliary Transport Particle B Motile Cilium Photoreceptor Connecting Cilium Ciliary Basal Body Dendrite Terminus Extracellular Vesicular Exosome Primary Cilium Ciliary Tip Ciliary Base
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Protein Transporter Activity Histone Deacetylase Binding Poly(A) RNA Binding	Opsin Binding Protein Binding
	Biological Process	Regulation Of DNA Recombination DNA Metabolic Process NLS-bearing Protein Import Into Nucleus Viral Process Cytokine-mediated Signaling Pathway	Kidney Development Organelle Organization Smoothened Signaling Pathway Visual Learning Protein Localization To Golgi Apparatus Photoreceptor Cell Outer Segment Organization Opsin Transport Intraciliary Transport Cilium Assembly Centrosome Localization Cardiac Muscle Cell Differentiation Regulation Of Canonical Wnt Signaling Pathway Neural Precursor Cell Proliferation Protein Localization To Cilium Regulation Of Cilium Assembly Regulation Of Autophagic Vacuole Assembly
Pathways		ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes	Organelle biogenesis and maintenance Assembly of the primary cilium Intraflagellar transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		104 interactors: ACTN1 ACTN4 ANKIB1 AP2B1 APOBEC1 APP ARL4A ARL5A BRCA1 BTBD2 CASP2 CCDC107 CDA CDK5RAP3 CHD3 CHEK2 CORO1B CREB3L3 CREBBP CSE1L CSNK1A1 CUL4B DCTN2 DDIT3 EP300 EPB41 FEZ2 FN1 FTH1 GART GMCL1 GRB2 H1F0 HAP1 HMG20A HNRNPC HOMER2 HOMEZ HSPA4 IFT20 IMMT INO80E ITK JUN KLC4 KPNB1 KRT18 KRT40 KRT8 LAMB2 LEF1 LZTS2 MAGED1 MAGEH1 MDFI MLH1 MORC3 MVP MYC NECAB2 NFKBIB NMNAT1 NR3C1 NUP153 NUP50 NUP62 NUTM1 PAX5 PLAG1 PNMA5 PRKD3 PTMA RAG1 RAN RANBP2 RBM48 RBPMS RECQL RELA RELB RGL2 RILP RNMT SART3 SERTAD3 SGK1 SLC2A2 SPRY1 SRPK1 TADA2A TAF3 TAF8 TANK TBPL2 TP53 TRAF1 TRIM54 TSC22D4 TXNIP UBR5 USHBP1 ZBTB7B ZC3H12A ZNF131	29 interactors: ABI2 BLOC1S6 CCDC53 CCDC67 CROCCP2 DISC1 DTNBP1 EMILIN1 EXOC7 FBF1 FSD2 GOLGA2 HAUS1 HTT IFT57 KIF3B KPNA2 KRT13 KXD1 MED4 NDC80 NUP54 NUP62 PSMA1 PTPN12 TREX1 USHBP1 WASF1 ZDHHC17
Entrez ID		3838	90410
HPRD ID		02818	17137
Ensembl ID		ENSG00000182481	ENSG00000109083
Uniprot IDs		P52292 Q7Z726	Q8IY31
PDB IDs		1EFX 1QGK 1QGR 3FEX 3FEY 4E4V
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Cellular Process RNA Biosynthetic Process Gene Expression Response To Stimulus Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Cell Death Death Apoptotic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process Programmed Cell Death Viral Process Organelle Organization Regulation Of Nucleic Acid-templated Transcription Signal Transduction Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Developmental Process Regulation Of Transcription, DNA-templated Signaling Positive Regulation Of Transcription, DNA-templated Protein Localization To Nucleus Macromolecule Biosynthetic Process Cellular Localization Cell Cycle Negative Regulation Of Biosynthetic Process Cell Communication Negative Regulation Of Nucleic Acid-templated Transcription Cellular Process Negative Regulation Of RNA Biosynthetic Process Cell Cycle Process Response To Stress Positive Regulation Of Gene Expression Nucleocytoplasmic Transport Negative Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Response To Abiotic Stimulus Negative Regulation Of Transcription, DNA-templated Nuclear Transport Positive Regulation Of Macromolecule Biosynthetic Process Multicellular Organismal Development	Organelle Organization Microtubule-based Process Cytoskeleton Organization Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Mitotic Cell Cycle Anterograde Axon Cargo Transport Mitotic Cell Cycle Process Microtubule Cytoskeleton Organization Microtubule-based Movement Establishment Of Organelle Localization Cellular Localization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Membrane Organization Establishment Of Localization In Cell Positive Regulation Of Actin Nucleation Establishment Of Vesicle Localization Cell Cycle Vesicle Localization Organelle Localization Cell Cycle Process Organelle Assembly Protein Localization Movement Of Cell Or Subcellular Component Centrosome Organization Intracellular Transport Nucleocytoplasmic Transport Anterograde Synaptic Vesicle Transport Nuclear Transport Rac Protein Signal Transduction Microtubule Organizing Center Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Establishment Of Cell Polarity Melanosome Organization Pigment Granule Organization Regulation Of Actin Nucleation Spindle Organization Protein Transport Vesicle Transport Along Microtubule Mitotic Nuclear Envelope Disassembly Establishment Of Protein Localization Cytoplasmic Transport Establishment Of Mitotic Spindle Orientation Nuclear Envelope Disassembly Establishment Or Maintenance Of Cell Polarity Mitotic Spindle Organization Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Neural Plate Formation
Tagcloud ?		aggressive aggressiveness assembled attempt carcinomas curable diagnostics disregarding eic emgd endometrial entities figo immunoreactivity interplay introducing malignancy mediator mfe microarrays nucleocytoplasmic precancerous regimens surgically tmas trp53 tumour untreatable uterus	anchors apparatus assembled caenorhabditis centrosomal chlamydomonas cilia cilium displaces dyf elipsa flag gmap210 golgi hspb11 ift172 ift25 ift54 ift54s ift88 immunoprecipitate intraflagellar liss localize motil orthologue orthologues traf3ip1
Tagcloud (Difference) ?		aggressive aggressiveness attempt carcinomas curable diagnostics disregarding eic emgd endometrial entities figo immunoreactivity interplay introducing malignancy mediator mfe microarrays nucleocytoplasmic precancerous regimens surgically tmas trp53 tumour untreatable uterus	anchors apparatus caenorhabditis centrosomal chlamydomonas cilia cilium displaces dyf elipsa flag gmap210 golgi hspb11 ift172 ift25 ift54 ift54s ift88 immunoprecipitate intraflagellar liss localize motil orthologue orthologues traf3ip1
Tagcloud (Intersection) ?		assembled