KPNA2 and ARL5A

Number of citations of the paper that reports this interaction (PMID 12414990)
7

Data Source:
HPRD (in vitro)

		KPNA2	ARL5A
Gene Name		karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	ADP-ribosylation factor-like 5A
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Membrane	Intracellular
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Protein Transporter Activity Histone Deacetylase Binding Poly(A) RNA Binding	GTP Binding
	Biological Process	Regulation Of DNA Recombination DNA Metabolic Process NLS-bearing Protein Import Into Nucleus Viral Process Cytokine-mediated Signaling Pathway	Small GTPase Mediated Signal Transduction
Pathways		ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS
Protein-Protein Interactions		104 interactors: ACTN1 ACTN4 ANKIB1 AP2B1 APOBEC1 APP ARL4A ARL5A BRCA1 BTBD2 CASP2 CCDC107 CDA CDK5RAP3 CHD3 CHEK2 CORO1B CREB3L3 CREBBP CSE1L CSNK1A1 CUL4B DCTN2 DDIT3 EP300 EPB41 FEZ2 FN1 FTH1 GART GMCL1 GRB2 H1F0 HAP1 HMG20A HNRNPC HOMER2 HOMEZ HSPA4 IFT20 IMMT INO80E ITK JUN KLC4 KPNB1 KRT18 KRT40 KRT8 LAMB2 LEF1 LZTS2 MAGED1 MAGEH1 MDFI MLH1 MORC3 MVP MYC NECAB2 NFKBIB NMNAT1 NR3C1 NUP153 NUP50 NUP62 NUTM1 PAX5 PLAG1 PNMA5 PRKD3 PTMA RAG1 RAN RANBP2 RBM48 RBPMS RECQL RELA RELB RGL2 RILP RNMT SART3 SERTAD3 SGK1 SLC2A2 SPRY1 SRPK1 TADA2A TAF3 TAF8 TANK TBPL2 TP53 TRAF1 TRIM54 TSC22D4 TXNIP UBR5 USHBP1 ZBTB7B ZC3H12A ZNF131	6 interactors: APP CBX1 CBX3 CBX5 KPNA2 NMT1
Entrez ID		3838	26225
HPRD ID		02818	12343
Ensembl ID		ENSG00000182481
Uniprot IDs		P52292 Q7Z726	Q9Y689
PDB IDs		1EFX 1QGK 1QGR 3FEX 3FEY 4E4V	1Z6Y 1ZJ6 2H16 2H17
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Cellular Process RNA Biosynthetic Process Gene Expression Response To Stimulus Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Cell Death Death Apoptotic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process Programmed Cell Death Viral Process Organelle Organization Regulation Of Nucleic Acid-templated Transcription Signal Transduction Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Developmental Process Regulation Of Transcription, DNA-templated Signaling Positive Regulation Of Transcription, DNA-templated Protein Localization To Nucleus Macromolecule Biosynthetic Process Cellular Localization Cell Cycle Negative Regulation Of Biosynthetic Process Cell Communication Negative Regulation Of Nucleic Acid-templated Transcription Cellular Process Negative Regulation Of RNA Biosynthetic Process Cell Cycle Process Response To Stress Positive Regulation Of Gene Expression Nucleocytoplasmic Transport Negative Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Response To Abiotic Stimulus Negative Regulation Of Transcription, DNA-templated Nuclear Transport Positive Regulation Of Macromolecule Biosynthetic Process Multicellular Organismal Development	Viral Process Synaptic Growth At Neuromuscular Junction N-terminal Peptidyl-glycine N-myristoylation Collateral Sprouting In Absence Of Injury Negative Regulation Of Cellular Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process N-terminal Protein Myristoylation Neuron Remodeling Protein Myristoylation Response To Light Stimulus Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Blood Coagulation Cellular Copper Ion Homeostasis Hemostasis Response To Radiation NLS-bearing Protein Import Into Nucleus Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle N-terminal Protein Amino Acid Modification Regulation Of Rhodopsin Mediated Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Rhodopsin Mediated Signaling Pathway Regulation Of Body Fluid Levels Mating Behavior Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Tagcloud ?		aggressive aggressiveness assembled attempt carcinomas curable diagnostics disregarding eic emgd endometrial entities figo immunoreactivity interplay introducing malignancy mediator mfe microarrays nucleocytoplasmic precancerous regimens surgically tmas trp53 tumour untreatable uterus	alteration anterograde apparatus arf arl5b arls cargo classic dispersed endosome endosomes gfp golgi hela localised mannose perturbation q70l rab retrograde rnai shiga t30n tagged tgn tgn38 toxin trans transport
Tagcloud (Difference) ?		aggressive aggressiveness assembled attempt carcinomas curable diagnostics disregarding eic emgd endometrial entities figo immunoreactivity interplay introducing malignancy mediator mfe microarrays nucleocytoplasmic precancerous regimens surgically tmas trp53 tumour untreatable uterus	alteration anterograde apparatus arf arl5b arls cargo classic dispersed endosome endosomes gfp golgi hela localised mannose perturbation q70l rab retrograde rnai shiga t30n tagged tgn tgn38 toxin trans transport
Tagcloud (Intersection) ?