TXNIP and SMURF2

  • Number of citations of the paper that reports this interaction (PMID 15231748)
  • 65
  • Data Source:
  • HPRD (two hybrid)

TXNIP

SMURF2

Gene Name thioredoxin interacting protein SMAD specific E3 ubiquitin protein ligase 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 14 interactors: DDIT4 ECD FHL1 HDAC1 HDAC3 ITCH KPNA2 PRKAA1 SCEL SMURF2 TXN TXNRD1 ZBTB16 ZBTB32 79 interactors: ACBD3 ACOX3 ANAPC5 ARHGAP5 ASH2L AXIN1 BTRC CANX CUEDC1 DAB2 DAZAP2 DGCR2 EGFR EPHA1 FAM175B FKBP4 FLNB GNG2 HDGFRP3 ING2 IRF3 IRF8 KLF5 LAPTM5 LATS1 MAVS NEK6 NKIRAS1 NRAS PPID PRICKLE1 PRICKLE2 RAB13 RAB14 RAB17 RAB22A RAB25 RAN RAP1B RASD2 RASL12 RHOA RHOD RLIM RNF11 RNF111 RNF2 RNF20 RPS27A RRAS2 RUNX2 RUNX3 SF3A2 SKIL SMAD1 SMAD2 SMAD3 SMAD5 SMAD6 SMAD7 SMAP1 SNRNP70 SOCS6 SPG20 SRSF4 TFPI2 TGFBR1 TMEM139 TNPO3 TRAF2 TRAF4 TSSK4 TXNIP UBC UBE2D1 UBE2D3 UBE2L3 YY1 ZBTB44
Entrez ID 10628 64750
HPRD ID 05964 06901
Ensembl ID ENSG00000117289
Uniprot IDs Q9H3M7 Q96DE7 Q9HAU4
PDB IDs 4GEI 4GEJ 1ZVD 2DJY 2JQZ 2KXQ 2LTZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
another  arrest  better  br  breast  bt474  causes  corresponding  g1  indicated  inversely  little  marker  microarray  noncancerous  os  p27  plays  previous  prognostic  r  regarding  sk  strong  taken  thioredoxin  tissue  transfection  validated 
autoinhibitory  biochemical  c2  catalytic  controlled  domain  dysregulation  e3  e3s  framework  hect  impaired  interaction  intramolecular  ligases  magnetic  maintaining  nedd4  nmr  noncovalent  regulate  regulators  resonance  state  structural  terminal  transthiolation  ub  ubiquitin 
Tagcloud (Difference) ?
another  arrest  better  br  breast  bt474  causes  corresponding  g1  indicated  inversely  little  marker  microarray  noncancerous  os  p27  plays  previous  prognostic  r  regarding  sk  strong  taken  thioredoxin  tissue  transfection  validated 
autoinhibitory  biochemical  c2  catalytic  controlled  domain  dysregulation  e3  e3s  framework  hect  impaired  interaction  intramolecular  ligases  magnetic  maintaining  nedd4  nmr  noncovalent  regulate  regulators  resonance  state  structural  terminal  transthiolation  ub  ubiquitin 
Tagcloud (Intersection) ?