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GLRX3 and ADAMTSL4
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
GLRX3
ADAMTSL4
Gene Name
glutaredoxin 3
ADAMTS-like 4
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cell Cortex
Z Disc
Extracellular Vesicular Exosome
Cellular_component
Interstitial Matrix
Endoplasmic Reticulum Lumen
Molecular Function
Protein Kinase C Binding
Protein Binding
Electron Carrier Activity
Protein Disulfide Oxidoreductase Activity
Poly(A) RNA Binding
Metal Ion Binding
Iron-sulfur Cluster Binding
Protease Binding
Metalloendopeptidase Activity
Protein Binding
Biological Process
Regulation Of The Force Of Heart Contraction
Negative Regulation Of Cardiac Muscle Hypertrophy
Cell Redox Homeostasis
Oxidation-reduction Process
Protein O-linked Glycosylation
Proteolysis
Apoptotic Process
Extracellular Matrix Organization
Protein O-linked Fucosylation
Positive Regulation Of Apoptotic Process
Post-translational Protein Modification
Cellular Protein Metabolic Process
Pathways
Post-translational protein modification
O-glycosylation of TSR domain-containing proteins
O-linked glycosylation
Drugs
Diseases
GWAS
HIV-1 susceptibility (
21160409
)
Rhegmatogenous retinal detachment (
23585552
)
Protein-Protein Interactions
57 interactors:
ADAMTSL4
ALKBH3
BOLA1
CBLB
CGGBP1
CIAPIN1
EFEMP2
FAM118A
FRA10AC1
GMCL1
GRN
HEXDC
IKZF1
KRT31
KRT38
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP13-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-2
LCE2D
MAP3K3
MAPK6
MAPKBP1
MOXD1
NADK
NOTCH2NL
OLFM3
PCSK5
PFDN5
PLSCR1
PRKCQ
PRKCZ
PRKD2
RGS20
SOX7
STAU1
TCF4
TMEM25
TRAF1
TRIM36
TRIM42
UGP2
ZBTB44
ZNF148
ZNF426
ZNF512B
ZNF544
106 interactors:
ADAMTSL5
AMMECR1
APOL6
AQP1
ARNT2
ASPSCR1
C19orf66
C6orf165
CATSPER1
CCDC26
CHCHD2
CLEC18A
COL8A1
CPNE7
CREB5
CST2
CTSB
CXCL16
CYP2S1
DGCR6
DIP2A
DLK2
DNPEP
DSCR8
EIF4E2
FAH
FAM124B
FARS2
FBLN1
FBXW5
FHL3
FKBP1B
FLNA
FRS3
GATA2
GIP
GLRX3
GMCL1P1
GNE
GNMT
GOLGA8EP
HGF
HOXA1
KIF1A
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-4
LCE1B
LCE2D
LCE3C
LCE3E
LCE4A
LGALS14
LINC00671
LMO1
LMO2
LONRF1
LRRC29
MAPKBP1
MID2
MORN3
MVP
NATD1
NMUR2
NTF4
NTN4
OLFM3
PID1
PIN1
PLSCR1
PRKAB2
PTGER3
RAB2B
RCHY1
RHOJ
SALL2
SLC23A1
SLC6A20
SMARCC1
SORBS3
SPATA8
SPINK2
SPRY2
STK16
SUSD6
TAPBPL
TCEA2
TMEM150A
TMSB4XP6
TOP3B
TRIM42
TRIP6
TSSK3
TUBGCP4
ZNF417
ZNF587
Entrez ID
10539
54507
HPRD ID
10153
18237
Ensembl ID
ENSG00000108010
ENSG00000143382
Uniprot IDs
O76003
F8WAD0
Q6UY14
Q9UFG7
PDB IDs
2DIY
2WZ9
2YAN
3ZYW
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Developmental Process
Positive Regulation Of Interleukin-4 Production
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of RNA Metabolic Process
Regulation Of Interleukin-4 Production
Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation
Regulation Of Cell Activation
Regulation Of T Cell Activation
Cell Death
Death
Multicellular Organismal Development
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Alpha-beta T Cell Differentiation
Positive Regulation Of Epithelial Cell Proliferation
Anatomical Structure Development
Positive Regulation Of Neutrophil Differentiation
Renin Secretion Into Blood Stream
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Insulin Receptor Signaling Pathway
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Regulation Of Cellular Process
Transcription, DNA-templated
Regulation Of T Cell Receptor Signaling Pathway
Embryonic Digestive Tract Development
Positive Regulation Of Immune System Process
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Regulation Of Cell Adhesion
Positive Regulation Of Protein Metabolic Process
Regulation Of Signal Transduction
RNA Biosynthetic Process
Regulation Of Lymphocyte Activation
Protein Kinase D Signaling
Positive Regulation Of T-helper 2 Cell Activation
Oxidative Single-stranded DNA Demethylation
Positive Regulation Of Interleukin-13 Secretion
Positive Regulation Of Interleukin-5 Secretion
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Renal Response To Blood Flow Involved In Circulatory Renin-angiotensin Regulation Of Systemic Arterial Blood Pressure
Platelet Activation
Regulation Of Insulin Receptor Signaling Pathway
Apoptotic Process
Positive Regulation Of T Cell Activation
Multicellular Organismal Development
Keratinization
Organ Development
Developmental Process
Keratinocyte Differentiation
System Development
Anatomical Structure Development
Epidermis Development
Tissue Development
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Epidermal Cell Differentiation
Sensory Organ Development
Response To Organic Substance
Organic Anion Transport
Positive Regulation Of Neuron Projection Regeneration
Regulation Of Transcription From RNA Polymerase II Promoter
Epithelium Development
Cellular Response To Thyroid Hormone Stimulus
MRNA Transcription From RNA Polymerase II Promoter
Skin Development
Positive Regulation Of Transcription, DNA-templated
Transepithelial Transport
Semicircular Canal Development
Positive Regulation Of Gene Expression
Regulation Of Branching Involved In Salivary Gland Morphogenesis
MRNA Transcription
Response To Thyroid Hormone
Negative Regulation Of Hydrolase Activity
Cell Differentiation
Negative Regulation Of Protein Metabolic Process
Cellular Response To Organic Substance
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Tagcloud
?
abl
baalc
bcr
cd83
ciita
council
ctnnd1
e2993
gab1
gli1
hubs
il15
irs1
p185bcr
p210bcr
pilrb
ptp4a3
rab21
serpinb9
spp1
spry1
supervised
transcriptomic
tspan16
ukall
underexpressed
unsupervised
xbp1
xii
Tagcloud (Difference)
?
abl
baalc
bcr
cd83
ciita
council
ctnnd1
e2993
gab1
gli1
hubs
il15
irs1
p185bcr
p210bcr
pilrb
ptp4a3
rab21
serpinb9
spp1
spry1
supervised
transcriptomic
tspan16
ukall
underexpressed
unsupervised
xbp1
xii
Tagcloud (Intersection)
?