GLRX3 and TRIM42

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GLRX3	TRIM42
Gene Name		glutaredoxin 3	tripartite motif containing 42
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cell Cortex Z Disc Extracellular Vesicular Exosome	Intracellular
	Molecular Function	Protein Kinase C Binding Protein Binding Electron Carrier Activity Protein Disulfide Oxidoreductase Activity Poly(A) RNA Binding Metal Ion Binding Iron-sulfur Cluster Binding	Zinc Ion Binding
	Biological Process	Regulation Of The Force Of Heart Contraction Negative Regulation Of Cardiac Muscle Hypertrophy Cell Redox Homeostasis Oxidation-reduction Process
Pathways
Drugs
Diseases
GWAS		HIV-1 susceptibility ( 21160409)
Protein-Protein Interactions		57 interactors: ADAMTSL4 ALKBH3 BOLA1 CBLB CGGBP1 CIAPIN1 EFEMP2 FAM118A FRA10AC1 GMCL1 GRN HEXDC IKZF1 KRT31 KRT38 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP13-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE2D MAP3K3 MAPK6 MAPKBP1 MOXD1 NADK NOTCH2NL OLFM3 PCSK5 PFDN5 PLSCR1 PRKCQ PRKCZ PRKD2 RGS20 SOX7 STAU1 TCF4 TMEM25 TRAF1 TRIM36 TRIM42 UGP2 ZBTB44 ZNF148 ZNF426 ZNF512B ZNF544	63 interactors: ADAMTSL4 ARMC7 ARNT2 ARRDC3 BEX2 C1orf109 CARD9 CCDC33 CCDC36 CDCA7L CEP70 EFHC2 EMD FAM103A1 FAM208B GLI1 GLRX3 GLYCTK GOLGA2 HOXA1 IKZF3 IQUB KCTD9 KLHL38 KRT13 KRT15 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP26-1 KRTAP3-2 KRTAP4-2 L3MBTL2 LONRF1 LZTS2 MAGOHB MEOX2 MFAP1 MID2 MTUS2 MVP NOTCH2NL PLSCR1 PNMA1 PSMA1 PSMD9 PTGER3 RCOR3 RUNX1T1 SCNM1 SPERT SSX2IP STK16 TRAF1 TRAF2 TRAPPC2B TRIM23 TRIM27 TXNDC5 VPS37A YWHAQ ZBTB1
Entrez ID		10539	287015
HPRD ID		10153	15559
Ensembl ID		ENSG00000108010	ENSG00000155890
Uniprot IDs		O76003	Q8IWZ5
PDB IDs		2DIY 2WZ9 2YAN 3ZYW
Enriched GO Terms of Interacting Partners?		Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Developmental Process Positive Regulation Of Interleukin-4 Production Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Interleukin-4 Production Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation Regulation Of Cell Activation Regulation Of T Cell Activation Cell Death Death Multicellular Organismal Development Positive Regulation Of Interleukin-2 Production Positive Regulation Of Alpha-beta T Cell Differentiation Positive Regulation Of Epithelial Cell Proliferation Anatomical Structure Development Positive Regulation Of Neutrophil Differentiation Renin Secretion Into Blood Stream Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Insulin Receptor Signaling Pathway Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Cellular Process Transcription, DNA-templated Regulation Of T Cell Receptor Signaling Pathway Embryonic Digestive Tract Development Positive Regulation Of Immune System Process Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Cell Adhesion Positive Regulation Of Protein Metabolic Process Regulation Of Signal Transduction RNA Biosynthetic Process Regulation Of Lymphocyte Activation Protein Kinase D Signaling Positive Regulation Of T-helper 2 Cell Activation Oxidative Single-stranded DNA Demethylation Positive Regulation Of Interleukin-13 Secretion Positive Regulation Of Interleukin-5 Secretion Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Renal Response To Blood Flow Involved In Circulatory Renin-angiotensin Regulation Of Systemic Arterial Blood Pressure Platelet Activation Regulation Of Insulin Receptor Signaling Pathway Apoptotic Process Positive Regulation Of T Cell Activation	Gene Expression Regulation Of Apoptotic Process Cell Death Regulation Of Cell Death Death RNA Metabolic Process Transcription, DNA-templated Regulation Of Canonical Wnt Signaling Pathway RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Wnt Signaling Pathway Protein Polyubiquitination Regulation Of Signaling Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Viral Release From Host Cell Regulation Of Signal Transduction Apoptotic Process Negative Regulation Of Viral Process Positive Regulation Of Ligase Activity Negative Regulation Of Wnt Signaling Pathway Programmed Cell Death Regulation Of Cellular Process Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Ubiquitination Regulation Of Gene Expression Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Protein Modification By Small Protein Conjugation Temperature Homeostasis Cellular Nitrogen Compound Metabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Protein K63-linked Ubiquitination Regulation Of Metabolic Process Protein Trimerization Positive Regulation Of Pro-T Cell Differentiation Abducens Nerve Formation Negative Regulation Of Locomotion Involved In Locomotory Behavior Optokinetic Behavior Negative Regulation Of Heat Generation Recruitment Of MRNA Capping Enzyme To RNA Polymerase II Holoenzyme Complex Positive Regulation Of Protein Ubiquitination Positive Regulation Of Signal Transduction
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