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GLRX3 and GRN
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
GLRX3
GRN
Gene Name
glutaredoxin 3
granulin
Image
Gene Ontology Annotations
Cellular Component
Cell Cortex
Z Disc
Extracellular Vesicular Exosome
Extracellular Space
Mitochondrion
Intracellular Membrane-bounded Organelle
Extracellular Vesicular Exosome
Molecular Function
Protein Kinase C Binding
Protein Binding
Electron Carrier Activity
Protein Disulfide Oxidoreductase Activity
Poly(A) RNA Binding
Metal Ion Binding
Iron-sulfur Cluster Binding
Cytokine Activity
Protein Binding
Growth Factor Activity
Poly(A) RNA Binding
Biological Process
Regulation Of The Force Of Heart Contraction
Negative Regulation Of Cardiac Muscle Hypertrophy
Cell Redox Homeostasis
Oxidation-reduction Process
Blastocyst Hatching
Signal Transduction
Embryo Implantation
Positive Regulation Of Epithelial Cell Proliferation
Pathways
Drugs
Diseases
GWAS
HIV-1 susceptibility (
21160409
)
Intracranial volume (
22504418
)
Protein-Protein Interactions
57 interactors:
ADAMTSL4
ALKBH3
BOLA1
CBLB
CGGBP1
CIAPIN1
EFEMP2
FAM118A
FRA10AC1
GMCL1
GRN
HEXDC
IKZF1
KRT31
KRT38
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP13-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-2
LCE2D
MAP3K3
MAPK6
MAPKBP1
MOXD1
NADK
NOTCH2NL
OLFM3
PCSK5
PFDN5
PLSCR1
PRKCQ
PRKCZ
PRKD2
RGS20
SOX7
STAU1
TCF4
TMEM25
TRAF1
TRIM36
TRIM42
UGP2
ZBTB44
ZNF148
ZNF426
ZNF512B
ZNF544
37 interactors:
ARFGAP1
ATN1
ATXN7
CACNA1A
CCDC33
CCNG1
CCNT1
CDK9
CRKL
CRY1
DLK1
DLX2
ELANE
FAM131C
FANCL
FRAT1
GFI1B
GLRX3
HK3
HOXA1
HSPG2
KRT18
KRTAP10-7
KRTAP26-1
NLK
OTX1
PIK3R2
POT1
PRKAB2
RAC1
SGTA
SLPI
SMAD9
TAT
TGM2
TOP3B
YY1
Entrez ID
10539
2896
HPRD ID
10153
00733
Ensembl ID
ENSG00000108010
ENSG00000030582
Uniprot IDs
O76003
P28799
PDB IDs
2DIY
2WZ9
2YAN
3ZYW
1G26
2JYE
2JYT
2JYU
2JYV
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Developmental Process
Positive Regulation Of Interleukin-4 Production
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of RNA Metabolic Process
Regulation Of Interleukin-4 Production
Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation
Regulation Of Cell Activation
Regulation Of T Cell Activation
Cell Death
Death
Multicellular Organismal Development
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Alpha-beta T Cell Differentiation
Positive Regulation Of Epithelial Cell Proliferation
Anatomical Structure Development
Positive Regulation Of Neutrophil Differentiation
Renin Secretion Into Blood Stream
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Insulin Receptor Signaling Pathway
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Regulation Of Cellular Process
Transcription, DNA-templated
Regulation Of T Cell Receptor Signaling Pathway
Embryonic Digestive Tract Development
Positive Regulation Of Immune System Process
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Regulation Of Cell Adhesion
Positive Regulation Of Protein Metabolic Process
Regulation Of Signal Transduction
RNA Biosynthetic Process
Regulation Of Lymphocyte Activation
Protein Kinase D Signaling
Positive Regulation Of T-helper 2 Cell Activation
Oxidative Single-stranded DNA Demethylation
Positive Regulation Of Interleukin-13 Secretion
Positive Regulation Of Interleukin-5 Secretion
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Renal Response To Blood Flow Involved In Circulatory Renin-angiotensin Regulation Of Systemic Arterial Blood Pressure
Platelet Activation
Regulation Of Insulin Receptor Signaling Pathway
Apoptotic Process
Positive Regulation Of T Cell Activation
Response To Organic Substance
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Central Nervous System Development
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Cellular Process
Regulation Of Metabolic Process
Brain Development
Regulation Of Kinase Activity
Head Development
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Positive Regulation Of Cellular Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Response To Organic Substance
Transcription, DNA-templated
Regulation Of Cellular Protein Metabolic Process
Pattern Specification Process
RNA Biosynthetic Process
Regulation Of Phosphorylation
Transforming Growth Factor Beta Receptor Signaling Pathway
Organ Morphogenesis
Anatomical Structure Morphogenesis
Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Homeostatic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Response To Stimulus
Positive Regulation Of Metabolic Process
Embryonic Organ Morphogenesis
Regulation Of Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Embryonic Skeletal System Development
Response To Light Stimulus
Hindbrain Development
Regulation Of Protein Metabolic Process
Regulation Of Signaling
Cellular Response To Transforming Growth Factor Beta Stimulus
Regulation Of Phosphorus Metabolic Process
Pons Development
Cell Surface Receptor Signaling Pathway
Response To Stimulus
Response To Transforming Growth Factor Beta
Positive Regulation Of Gene Expression
Macromolecule Biosynthetic Process
Regulation Of Signal Transduction
Cellular Aromatic Compound Metabolic Process
Central Nervous System Neuron Differentiation
Anatomical Structure Development
Positive Regulation Of Transcription, DNA-templated
Tagcloud
?
arose
backcrosses
bareskin
bsk
chr
clustered
corneal
den
denuded
facility
granulin
hair
intersubspecific
junctional
jup
keratin
kinds
krt1
linkage
mapped
opacity
plakoglobin
portion
rara
recombination
resembling
rex
rim3
spontaneously
Tagcloud (Difference)
?
arose
backcrosses
bareskin
bsk
chr
clustered
corneal
den
denuded
facility
granulin
hair
intersubspecific
junctional
jup
keratin
kinds
krt1
linkage
mapped
opacity
plakoglobin
portion
rara
recombination
resembling
rex
rim3
spontaneously
Tagcloud (Intersection)
?