GLRX3 and MOXD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GLRX3	MOXD1
Description		glutaredoxin 3	monooxygenase DBH like 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cell Cortex Z Disc Dendrite Iron-sulfur Cluster Assembly Complex	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Secretory Granule Membrane
	Molecular Function	RNA Binding Protein Kinase C Binding Protein Binding Identical Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding	Catalytic Activity Monooxygenase Activity Dopamine Beta-monooxygenase Activity Copper Ion Binding Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Ascorbate As One Donor, And Incorporation Of One Atom Of Oxygen Metal Ion Binding
	Biological Process	Regulation Of The Force Of Heart Contraction Intracellular Iron Ion Homeostasis Negative Regulation Of Cardiac Muscle Hypertrophy Iron-sulfur Cluster Assembly [2Fe-2S] Cluster Assembly Cell Redox Homeostasis	Octopamine Biosynthetic Process Dopamine Catabolic Process Norepinephrine Biosynthetic Process
Pathways		Iron uptake and transport
Drugs
Diseases
GWAS		Alcohol dependence ( 26365420) Colorectal cancer ( 34062886) Copper levels ( 26025379) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) HIV-1 susceptibility ( 21160409) Mean corpuscular volume ( 32888494) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Sleep end time ( 33075057) Triglyceride levels x short total sleep time interaction (1df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)	Height ( 31562340) Obesity-related traits ( 23251661)
Interacting Genes		99 interacting genes: ADAMTSL3 ADAMTSL4 ALKBH3 BCL6 BOLA2 BOLA2B BOLA3 CA9 CBLB CCHCR1 CEBPA CERCAM CGGBP1 CIAPIN1 COL8A1 DANCR EFEMP2 ERBB2 FAM118A FRA10AC1 GATA1 GMCL1 GNG13 GRN HEXD HSD3B7 IHO1 IKZF1 IL10 IRX6 KLHDC9 KRT31 KRT38 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP13-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-3 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE2D LNX1 LNX2 LRIG1 MAP3K3 MAPK6 MAPKBP1 MDFI METAP1 MOXD1 NADK NOTCH2NLA NTF4 OLFM3 PCSK5 PFDN5 PLEKHG4B PLSCR1 PRKCQ PRKCZ RCOR3 RECK RGS20 SMARCC1 SOX7 STAU1 STRA6 TCF4 TCL1B TLE5 TMEM25 TRAF1 TRIM36 TRIM42 UGP2 ZBTB44 ZNF124 ZNF148 ZNF23 ZNF426 ZNF490 ZNF512B ZNF544 ZNF774	2 interacting genes: CSNK2B GLRX3
Entrez ID		10539	26002
HPRD ID		10153	10093
Ensembl ID		ENSG00000108010	ENSG00000079931
Uniprot IDs		A0A140VJK1 O76003	Q6UVY6
PDB IDs		2DIY 2WZ9 2YAN 3ZYW
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Hair Cycle Iron-sulfur Cluster Assembly Protein Binding Iron-sulfur Cluster Assembly Complex Identical Protein Binding	Positive Regulation Of Activin Receptor Signaling Pathway Protein Kinase CK2 Complex Negative Regulation Of Viral Life Cycle Symbiont-mediated Disruption Of Host Cell PML Body Release From Viral Latency Endothelial Tube Morphogenesis Adiponectin-activated Signaling Pathway Iron-sulfur Cluster Assembly Complex [2Fe-2S] Cluster Assembly Protein Kinase Regulator Activity PcG Protein Complex Peptidyl-threonine Phosphorylation Regulation Of Activin Receptor Signaling Pathway Iron-sulfur Cluster Assembly Regulation Of The Force Of Heart Contraction Positive Regulation Of SMAD Protein Signal Transduction Negative Regulation Of Muscle Hypertrophy Cell Redox Homeostasis Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Kinase C Binding Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of SMAD Protein Signal Transduction Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Viral Process Negative Regulation Of Endothelial Cell Migration Intracellular Iron Ion Homeostasis Regulation Of Cardiac Muscle Hypertrophy Iron-sulfur Cluster Binding Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Identical Protein Binding Epithelial Tube Morphogenesis Regulation Of Viral Life Cycle Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway PML Body Negative Regulation Of Protein Catabolic Process Ficolin-1-rich Granule Lumen Secretory Granule Lumen Regulation Of Blood Vessel Endothelial Cell Migration
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