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GLRX3 and PRKCQ
Number of citations of the paper that reports this interaction (PMID
10636891
)
30
Data Source:
HPRD
(in vitro, two hybrid, in vivo)
GLRX3
PRKCQ
Gene Name
glutaredoxin 3
protein kinase C, theta
Image
Gene Ontology Annotations
Cellular Component
Cell Cortex
Z Disc
Extracellular Vesicular Exosome
Immunological Synapse
Cytosol
Plasma Membrane
Molecular Function
Protein Kinase C Binding
Protein Binding
Electron Carrier Activity
Protein Disulfide Oxidoreductase Activity
Poly(A) RNA Binding
Metal Ion Binding
Iron-sulfur Cluster Binding
Protein Serine/threonine Kinase Activity
Protein Kinase C Activity
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Metal Ion Binding
Biological Process
Regulation Of The Force Of Heart Contraction
Negative Regulation Of Cardiac Muscle Hypertrophy
Cell Redox Homeostasis
Oxidation-reduction Process
Regulation Of Cell Growth
Regulation Of Transcription, DNA-templated
Protein Phosphorylation
Membrane Protein Ectodomain Proteolysis
Apoptotic Process
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Inflammatory Response
Axon Guidance
Blood Coagulation
Phototransduction, Visible Light
Rhodopsin Mediated Signaling Pathway
Protein Ubiquitination
Regulation Of Rhodopsin Mediated Signaling Pathway
Platelet Activation
Positive Regulation Of Interleukin-17 Production
Positive Regulation Of Interleukin-4 Production
Intracellular Signal Transduction
Fc-epsilon Receptor Signaling Pathway
Positive Regulation Of T Cell Proliferation
Positive Regulation Of Interleukin-2 Biosynthetic Process
Innate Immune Response
Negative Regulation Of Insulin Receptor Signaling Pathway
T Cell Receptor Signaling Pathway
Positive Regulation Of T Cell Activation
Positive Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of T Cell Apoptotic Process
Regulation Of Platelet Aggregation
Positive Regulation Of T-helper 17 Type Immune Response
Positive Regulation Of T-helper 2 Cell Activation
Pathways
G alpha (q) signalling events
Signaling by GPCR
Downstream TCR signaling
Axon guidance
Effects of PIP2 hydrolysis
FCERI mediated NF-kB activation
Inactivation, recovery and regulation of the phototransduction cascade
Gastrin-CREB signalling pathway via PKC and MAPK
The phototransduction cascade
Programmed Cell Death
G alpha (z) signalling events
Netrin-1 signaling
Innate Immune System
Apoptotic cleavage of cellular proteins
Apoptotic execution phase
Diseases associated with visual transduction
G alpha (q) signalling events
GPCR downstream signaling
TCR signaling
Visual phototransduction
Fc epsilon receptor (FCERI) signaling
Platelet activation, signaling and aggregation
Adaptive Immune System
Drugs
Staurosporine
Phosphonothreonine
Phosphonoserine
Diseases
GWAS
HIV-1 susceptibility (
21160409
)
Asthma (bronchodilator response) (
23508266
)
Body mass index (asthmatics) (
23517042
)
Immune response to smallpox vaccine (IL-6) (
22542470
)
Rheumatoid arthritis (
18794853
20453842
)
Type 1 diabetes (
19430480
18978792
)
Protein-Protein Interactions
57 interactors:
ADAMTSL4
ALKBH3
BOLA1
CBLB
CGGBP1
CIAPIN1
EFEMP2
FAM118A
FRA10AC1
GMCL1
GRN
HEXDC
IKZF1
KRT31
KRT38
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP13-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-2
LCE2D
MAP3K3
MAPK6
MAPKBP1
MOXD1
NADK
NOTCH2NL
OLFM3
PCSK5
PFDN5
PLSCR1
PRKCQ
PRKCZ
PRKD2
RGS20
SOX7
STAU1
TCF4
TMEM25
TRAF1
TRIM36
TRIM42
UGP2
ZBTB44
ZNF148
ZNF426
ZNF512B
ZNF544
28 interactors:
AKT1
BTK
CARD11
CASP3
CBL
CHUK
CISH
FYN
GLRX3
GRM5
HABP4
ICAM3
IKBKB
IKBKG
IRS1
LCK
LYN
MARK3
MSN
NFE2L2
RASGRP3
SELL
STK39
TAL1
VAV1
WIPF1
YWHAG
YWHAQ
Entrez ID
10539
5588
HPRD ID
10153
02710
Ensembl ID
ENSG00000108010
ENSG00000065675
Uniprot IDs
O76003
Q04759
PDB IDs
2DIY
2WZ9
2YAN
3ZYW
1XJD
2ENJ
2ENN
2ENZ
2JED
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Developmental Process
Positive Regulation Of Interleukin-4 Production
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of RNA Metabolic Process
Regulation Of Interleukin-4 Production
Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation
Regulation Of Cell Activation
Regulation Of T Cell Activation
Cell Death
Death
Multicellular Organismal Development
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Alpha-beta T Cell Differentiation
Positive Regulation Of Epithelial Cell Proliferation
Anatomical Structure Development
Positive Regulation Of Neutrophil Differentiation
Renin Secretion Into Blood Stream
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Insulin Receptor Signaling Pathway
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Regulation Of Cellular Process
Transcription, DNA-templated
Regulation Of T Cell Receptor Signaling Pathway
Embryonic Digestive Tract Development
Positive Regulation Of Immune System Process
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Regulation Of Cell Adhesion
Positive Regulation Of Protein Metabolic Process
Regulation Of Signal Transduction
RNA Biosynthetic Process
Regulation Of Lymphocyte Activation
Protein Kinase D Signaling
Positive Regulation Of T-helper 2 Cell Activation
Oxidative Single-stranded DNA Demethylation
Positive Regulation Of Interleukin-13 Secretion
Positive Regulation Of Interleukin-5 Secretion
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Renal Response To Blood Flow Involved In Circulatory Renin-angiotensin Regulation Of Systemic Arterial Blood Pressure
Platelet Activation
Regulation Of Insulin Receptor Signaling Pathway
Apoptotic Process
Positive Regulation Of T Cell Activation
Fc Receptor Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Regulation Of Immune System Process
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Regulation Of Immune Response
Immune Response-activating Cell Surface Receptor Signaling Pathway
Antigen Receptor-mediated Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Intracellular Signal Transduction
Innate Immune Response
Neurotrophin TRK Receptor Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Immune System Process
Neurotrophin Signaling Pathway
Regulation Of Apoptotic Process
Immune System Process
T Cell Costimulation
Regulation Of Cell Death
Positive Regulation Of Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Signal Transduction
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Positive Regulation Of Immune Response
Regulation Of Intracellular Signal Transduction
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
T Cell Receptor Signaling Pathway
Signal Transduction
Regulation Of Signaling
Immune Response
Regulation Of Lymphocyte Activation
Cellular Response To Growth Factor Stimulus
Phosphatidylinositol-mediated Signaling
Defense Response
Lymphocyte Homeostasis
Signaling
Response To Growth Factor
Cell Communication
Response To Organic Substance
Response To Stress
Cellular Response To Stimulus
Regulation Of T Cell Activation
Leukocyte Homeostasis
Phosphorylation
Positive Regulation Of Cell Activation
Regulation Of Cell Activation
Cell Surface Receptor Signaling Pathway
Cellular Response To Peptide Hormone Stimulus
Tagcloud
?
aurkb
bub1b
ccnb1
cd247
cd3d
cd3g
cd8a
cdc20
cdca8
cenpa
cytoscape
dihydroxyfluorane
epstain
generank
hindering
itgb5
itk
kif2c
lcp2
limma
lymphoblasts
mad2l1
nup37
pik3r3
plcg2
rpa3
softwares
vav3
zap70
Tagcloud (Difference)
?
aurkb
bub1b
ccnb1
cd247
cd3d
cd3g
cd8a
cdc20
cdca8
cenpa
cytoscape
dihydroxyfluorane
epstain
generank
hindering
itgb5
itk
kif2c
lcp2
limma
lymphoblasts
mad2l1
nup37
pik3r3
plcg2
rpa3
softwares
vav3
zap70
Tagcloud (Intersection)
?