KEAP1 and SQSTM1

  • Number of citations of the paper that reports this interaction (PMID 23795962)
  • 5
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology, affinity chromatography technology)

KEAP1

SQSTM1

Gene Name kelch-like ECH-associated protein 1 sequestosome 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 38 interactors: AK4 AMER1 ATG5 BAD BPTF CAT CCNB1IP1 CLU DPP3 ETF1 FAM117B FAM46A GLRX5 GYPA IPO11 IRF1 KLHL3 KPNA6 LSM3 MAD2L1 MAPKBP1 MYO7A NFE2L2 NUDT4 OXR1 PDCD6IP PIDD1 PRKAG1 PRKCE PTMA RECK RELA SNRPN SQSTM1 TERF1 TSC22D4 WDR83 ZSCAN32 74 interactors: ATXN3 BCL2 BMPR1B BPTF CALM1 CAMK2A CCNB1 CDC37 CDK1 CSNK2A1 DAZAP2 EEF1D EGLN3 FKBP4 GABARAPL1 GABARAPL2 GABRR1 GABRR2 GEMIN4 GRB14 GRIA1 GRIA2 GRIA3 IRAK1 KCNAB2 KEAP1 LCK LINC00341 MALT1 MAP1LC3A MAP1LC3B MAP2K5 MAP3K3 MAPK14 MBP MEIS2 MLH1 NBR1 NCOR1 NR2F2 NTRK1 NTRK2 NTRK3 OPTN PAWR PIK3CA PPHLN1 PRKCI PRKCZ RAD23A RELN RIPK1 RPL37 SMAD1 SMAD2 SMAD3 SMAD4 SMURF1 SNCA STXBP1 TGFBR1 TKT TOE1 TP53 TRAF6 TRIM55 TRIM63 TTN UBA52 UBB UBC ULK1 ULK2 YWHAZ
Entrez ID 9817 8878
HPRD ID 12079 03319
Ensembl ID ENSG00000079999 ENSG00000161011
Uniprot IDs Q14145 Q13501
PDB IDs 1U6D 1ZGK 2FLU 3VNG 3VNH 3ZGC 3ZGD 4IN4 4IQK 1Q02 2JY7 2JY8 2K0B 2KNV
Enriched GO Terms of Interacting Partners?
Tagcloud ?
acceptable  acts  antioxidant  antioxidants  cytoprotective  ech  enhances  exerted  extensive  h2o2  hydrogen  interference  kelch  maintained  managed  ndds  neurodegenerative  neuroprotection  neurotoxicity  nrf2  oxidative  peroxide  relieving  represses  rnai  sirna  speculated  suffered  u87mg 
aldh1a1  anxa1  bcar1  cldn1  crmp1  endpoint  folr1  foxm1  il12rb2  il7r  inconclusive  kiaa1524  lox  mcm7  mta1  mtdh  ncoa3  ndrg2  nedd9  nes  overview  pbk  ppm1d  principally  prognostication  qualifying  slc7a5  warranted  wnt1 
Tagcloud (Difference) ?
acceptable  acts  antioxidant  antioxidants  cytoprotective  ech  enhances  exerted  extensive  h2o2  hydrogen  interference  kelch  maintained  managed  ndds  neurodegenerative  neuroprotection  neurotoxicity  nrf2  oxidative  peroxide  relieving  represses  rnai  sirna  speculated  suffered  u87mg 
aldh1a1  anxa1  bcar1  cldn1  crmp1  endpoint  folr1  foxm1  il12rb2  il7r  inconclusive  kiaa1524  lox  mcm7  mta1  mtdh  ncoa3  ndrg2  nedd9  nes  overview  pbk  ppm1d  principally  prognostication  qualifying  slc7a5  warranted  wnt1 
Tagcloud (Intersection) ?