Gene Name |
kelch-like ECH-associated protein 1 |
nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
Image |
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No pdb structure |
Gene Ontology Annotations |
Cellular Component |
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Molecular Function |
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- Diphosphoinositol-polyphosphate Diphosphatase Activity
- SnoRNA Binding
- Metal Ion Binding
- M7G(5')pppN Diphosphatase Activity
- Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity
- Inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate Diphosphatase Activity
- Inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate Diphosphatase Activity
- Inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate Diphosphatase Activity
- Inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase Activity
- Inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity
- Inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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Protein-Protein Interactions |
38 interactors:
AK4
AMER1
ATG5
BAD
BPTF
CAT
CCNB1IP1
CLU
DPP3
ETF1
FAM117B
FAM46A
GLRX5
GYPA
IPO11
IRF1
KLHL3
KPNA6
LSM3
MAD2L1
MAPKBP1
MYO7A
NFE2L2
NUDT4
OXR1
PDCD6IP
PIDD1
PRKAG1
PRKCE
PTMA
RECK
RELA
SNRPN
SQSTM1
TERF1
TSC22D4
WDR83
ZSCAN32
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1 interactors:
KEAP1
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Entrez ID |
9817 |
11163 |
HPRD ID |
12079 |
14850 |
Ensembl ID |
ENSG00000079999
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ENSG00000173598
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Uniprot IDs |
Q14145
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Q9NZJ9
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PDB IDs |
1U6D
1ZGK
2FLU
3VNG
3VNH
3ZGC
3ZGD
4IN4
4IQK
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
acceptable
acts
antioxidant
antioxidants
cytoprotective
ech
enhances
exerted
extensive
h2o2
hydrogen
interference
kelch
maintained
managed
ndds
neurodegenerative
neuroprotection
neurotoxicity
nrf2
oxidative
peroxide
relieving
represses
rnai
sirna
speculated
suffered
u87mg
|
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Tagcloud (Difference) ? |
acceptable
acts
antioxidant
antioxidants
cytoprotective
ech
enhances
exerted
extensive
h2o2
hydrogen
interference
kelch
maintained
managed
ndds
neurodegenerative
neuroprotection
neurotoxicity
nrf2
oxidative
peroxide
relieving
represses
rnai
sirna
speculated
suffered
u87mg
|
|
Tagcloud (Intersection) ? |
|