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SQSTM1 and DAZAP2
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
SQSTM1
DAZAP2
Gene Name
sequestosome 1
DAZ associated protein 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Pre-autophagosomal Structure
Cytoplasmic MRNA Processing Body
Nucleoplasm
Cytoplasm
Lysosome
Late Endosome
Autophagic Vacuole
Endoplasmic Reticulum
Cytosol
Inclusion Body
Aggresome
PML Body
Cytoplasmic Vesicle
Extracellular Vesicular Exosome
Nucleus
Cytoplasm
Molecular Function
Protein Serine/threonine Kinase Activity
Protein Kinase C Binding
Protein Binding
Zinc Ion Binding
Protein Kinase Binding
Receptor Tyrosine Kinase Binding
SH2 Domain Binding
Identical Protein Binding
Protein Homodimerization Activity
Ubiquitin Binding
K63-linked Polyubiquitin Binding
Protein Binding
WW Domain Binding
Biological Process
Positive Regulation Of Protein Phosphorylation
Immune System Process
Protein Phosphorylation
Ubiquitin-dependent Protein Catabolic Process
Autophagy
Response To Stress
Protein Localization
Endosomal Transport
Macroautophagy
Positive Regulation Of Macroautophagy
Cell Differentiation
Intracellular Signal Transduction
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Ras Protein Signal Transduction
Neurotrophin TRK Receptor Signaling Pathway
Protein Heterooligomerization
Apoptotic Signaling Pathway
Pathways
Signaling by Interleukins
Signalling by NGF
NF-kB is activated and signals survival
p75NTR recruits signalling complexes
Cell death signalling via NRAGE, NRIF and NADE
NRIF signals cell death from the nucleus
p75NTR signals via NF-kB
Cytokine Signaling in Immune system
Interleukin-1 signaling
p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS
Protein-Protein Interactions
74 interactors:
ATXN3
BCL2
BMPR1B
BPTF
CALM1
CAMK2A
CCNB1
CDC37
CDK1
CSNK2A1
DAZAP2
EEF1D
EGLN3
FKBP4
GABARAPL1
GABARAPL2
GABRR1
GABRR2
GEMIN4
GRB14
GRIA1
GRIA2
GRIA3
IRAK1
KCNAB2
KEAP1
LCK
LINC00341
MALT1
MAP1LC3A
MAP1LC3B
MAP2K5
MAP3K3
MAPK14
MBP
MEIS2
MLH1
NBR1
NCOR1
NR2F2
NTRK1
NTRK2
NTRK3
OPTN
PAWR
PIK3CA
PPHLN1
PRKCI
PRKCZ
RAD23A
RELN
RIPK1
RPL37
SMAD1
SMAD2
SMAD3
SMAD4
SMURF1
SNCA
STXBP1
TGFBR1
TKT
TOE1
TP53
TRAF6
TRIM55
TRIM63
TTN
UBA52
UBB
UBC
ULK1
ULK2
YWHAZ
86 interactors:
AATF
ARID5A
ATXN1
ATXN1L
BAG3
BATF2
C1orf94
CALCOCO2
CCDC120
CDK4
CEP70
CLASRP
COL4A2
COL4A5
CXCL12
DAB1
DAZ1
DAZL
DCUN1D1
EPN1
EXD3
FAM168A
FAM46B
FAM46C
FBN3
GPSM1
HGS
HIP1
KRTAP19-5
KRTAP8-1
LASP1
LMO2
MED31
NDUFA5
NEDD4
NEDD4L
NOC4L
OPTN
OTULIN
PEF1
PLEKHB2
PLSCR1
POGZ
POLI
PRR20A
RABGEF1
RBFOX1
RBFOX2
RBPMS
RHOXF2
RNF115
RNF208
ROR2
RPS27A
SEPT2
SMAP2
SMURF2
SOX6
SQSTM1
STAM2
STAT6
TAX1BP1
TCF7L2
TEX37
TLE1
TNIP3
TOLLIP
UBA52
UBAC1
UBASH3A
UBASH3B
UBB
UBC
UBE2D4
UBE2E2
UBQLN4
USP5
VHLL
VPS37C
WDR73
WWP1
ZC3H10
ZFAND2B
ZFYVE9
ZNF34
ZNF581
Entrez ID
8878
9802
HPRD ID
03319
08463
Ensembl ID
ENSG00000161011
ENSG00000183283
Uniprot IDs
Q13501
E9PB45
Q15038
PDB IDs
1Q02
2JY7
2JY8
2K0B
2KNV
Enriched GO Terms of Interacting Partners
?
Cell Communication
Response To Growth Factor
Cellular Response To Growth Factor Stimulus
Cellular Response To Stimulus
Response To Stimulus
Positive Regulation Of Protein Metabolic Process
Regulation Of Protein Phosphorylation
Response To Stress
Regulation Of Phosphorylation
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Cellular Protein Metabolic Process
Signaling
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Modification Process
Regulation Of Phosphorus Metabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Phosphorylation
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Protein Kinase Activity
Phosphorylation
Cellular Response To Organic Substance
Regulation Of Kinase Activity
Positive Regulation Of Protein Kinase Activity
Signal Transduction
Regulation Of Signaling
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Signal Transduction
Positive Regulation Of Transferase Activity
Positive Regulation Of Kinase Activity
Regulation Of Cell Death
Negative Regulation Of Cell Death
Response To Organic Substance
Regulation Of Signal Transduction
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Neurotrophin Signaling Pathway
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Cellular Metabolic Process
Negative Regulation Of Programmed Cell Death
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Metabolic Process
Protein Phosphorylation
Activation Of Protein Kinase Activity
Membrane Organization
Neurotrophin TRK Receptor Signaling Pathway
Cellular Component Assembly
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Catalytic Activity
Cell Surface Receptor Signaling Pathway
Cellular Response To Stress
Negative Regulation Of Signal Transduction
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of Signaling
Negative Regulation Of ERBB Signaling Pathway
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Viral Protein Processing
Regulation Of ERBB Signaling Pathway
Protein Ubiquitination
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Signal Transduction
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Protein Polyubiquitination
Protein Modification By Small Protein Conjugation
Regulation Of Gene Expression
Cellular Response To Transforming Growth Factor Beta Stimulus
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Metabolic Process
Response To Transforming Growth Factor Beta
Virion Assembly
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Regulation Of Signaling
Intracellular Transport Of Virus
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Gene Expression
Positive Regulation Of Protein Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Positive Regulation Of Metabolic Process
Negative Regulation Of RNA Biosynthetic Process
Intracellular Receptor Signaling Pathway
RNA Metabolic Process
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Regulation Of Protein Metabolic Process
RNA Biosynthetic Process
Endosomal Transport
Regulation Of RNA Metabolic Process
Negative Regulation Of Biosynthetic Process
Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Type I Interferon Production
Transforming Growth Factor Beta Receptor Signaling Pathway
Modification-dependent Protein Catabolic Process
Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Tagcloud
?
aldh1a1
anxa1
bcar1
cldn1
crmp1
endpoint
folr1
foxm1
il12rb2
il7r
inconclusive
kiaa1524
lox
mcm7
mta1
mtdh
ncoa3
ndrg2
nedd9
nes
overview
pbk
ppm1d
principally
prognostication
qualifying
slc7a5
warranted
wnt1
Tagcloud (Difference)
?
aldh1a1
anxa1
bcar1
cldn1
crmp1
endpoint
folr1
foxm1
il12rb2
il7r
inconclusive
kiaa1524
lox
mcm7
mta1
mtdh
ncoa3
ndrg2
nedd9
nes
overview
pbk
ppm1d
principally
prognostication
qualifying
slc7a5
warranted
wnt1
Tagcloud (Intersection)
?