KEAP1 and CCNB1IP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KEAP1	CCNB1IP1
Gene Name		kelch-like ECH-associated protein 1	cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Endoplasmic Reticulum Microtubule Organizing Center Cytosol Midbody Cul3-RING Ubiquitin Ligase Complex	Synaptonemal Complex
	Molecular Function	Protein Binding Transcription Factor Binding	Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	In Utero Embryonic Development Transcription, DNA-templated Proteasomal Ubiquitin-independent Protein Catabolic Process Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Epidermal Cell Differentiation Cellular Response To Interleukin-4	Blastocyst Formation Reciprocal Meiotic Recombination Spermatid Development Protein Ubiquitination Chiasma Assembly
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		38 interactors: AK4 AMER1 ATG5 BAD BPTF CAT CCNB1IP1 CLU DPP3 ETF1 FAM117B FAM46A GLRX5 GYPA IPO11 IRF1 KLHL3 KPNA6 LSM3 MAD2L1 MAPKBP1 MYO7A NFE2L2 NUDT4 OXR1 PDCD6IP PIDD1 PRKAG1 PRKCE PTMA RECK RELA SNRPN SQSTM1 TERF1 TSC22D4 WDR83 ZSCAN32	9 interactors: APP CCNB1 EPM2AIP1 KEAP1 KRT15 NF2 PRKAA2 UBC UBE2L3
Entrez ID		9817	57820
HPRD ID		12079	07000
Ensembl ID		ENSG00000079999	ENSG00000100814
Uniprot IDs		Q14145	Q9NPC3
PDB IDs		1U6D 1ZGK 2FLU 3VNG 3VNH 3ZGC 3ZGD 4IN4 4IQK
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Regulation Of Apoptotic Process Regulation Of Protein Metabolic Process Regulation Of Cell Death Nucleobase-containing Compound Metabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Response To Virus Positive Regulation Of Interleukin-12 Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Cell Cycle Cellular Response To Nicotine Apoptotic Process Response To Other Organism Regulation Of Cellular Protein Metabolic Process Cellular Nitrogen Compound Metabolic Process Programmed Cell Death Response To Biotic Stimulus Cell Death Death Regulation Of Interleukin-12 Biosynthetic Process ADP Metabolic Process Response To Reactive Oxygen Species Catabolic Process Cellular Macromolecule Catabolic Process Positive Regulation Of Mucus Secretion Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Neurotrophin TRK Receptor Signaling Pathway Nitrogen Compound Metabolic Process Negative Regulation Of Chromosome Organization Positive Regulation Of Cell Cycle Process Neurotrophin Signaling Pathway Response To Oxidative Stress Regulation Of Mucus Secretion Regulation Of Proteolysis Negative Regulation Of Cell Cycle Regulation Of Cell Division Regulation Of Type I Interferon Production Negative Regulation Of Protein Catabolic Process Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Response To Hydrogen Peroxide Response To Drug Positive Regulation Of Cellular Metabolic Process Cellular Metabolic Process Macrophage Activation Metabolic Process Regulation Of Wound Healing	Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Positive Regulation Of Proteolysis Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Histone-serine Phosphorylation Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Transferase Activity Positive Regulation Of Metabolic Process Cellular Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Protein Ubiquitination Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Catalytic Activity Regulation Of Proteolysis Response To Organic Substance Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Protein Kinase Activity Proteasomal Protein Catabolic Process Cell Cycle Phase Transition Histone Phosphorylation Positive Regulation Of Catalytic Activity Regulation Of Kinase Activity Positive Regulation Of Cell Cycle Negative Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process Negative Regulation Of Protein Metabolic Process Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Catabolic Process Regulation Of Cell Cycle Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Cellular Response To Organic Substance Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cellular Protein Modification Process Cell Cycle Process Regulation Of Gene Expression Histone H3-S10 Phosphorylation Involved In Chromosome Condensation Response To DDT Cellular Response To Iron(III) Ion Regulation Of Mitotic Cell Cycle
Tagcloud ?		acceptable acts antioxidant antioxidants cytoprotective ech enhances exerted extensive h2o2 hydrogen interference kelch maintained managed ndds neurodegenerative neuroprotection neurotoxicity nrf2 oxidative peroxide relieving represses rnai sirna speculated suffered u87mg
Tagcloud (Difference) ?		acceptable acts antioxidant antioxidants cytoprotective ech enhances exerted extensive h2o2 hydrogen interference kelch maintained managed ndds neurodegenerative neuroprotection neurotoxicity nrf2 oxidative peroxide relieving represses rnai sirna speculated suffered u87mg
Tagcloud (Intersection) ?