MAP1LC3B and MRFAP1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		MAP1LC3B	MRFAP1
Gene Name		microtubule-associated protein 1 light chain 3 beta	Morf4 family associated protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Pre-autophagosomal Structure Autophagic Vacuole Membrane Intracellular Autophagic Vacuole Cytosol Microtubule Axoneme Endomembrane System Extrinsic Component Of Membrane Organelle Membrane Cytoplasmic Vesicle	Nucleus Nucleoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Microtubule Binding GABA Receptor Binding	Protein Binding
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation Cellular Response To Nitrogen Starvation Nucleophagy Membrane Fusion
Pathways
Drugs
Diseases
GWAS		Major depressive disorder ( 22472876)
Protein-Protein Interactions		50 interactors: AAMP ADD1 ADNP ARFGAP1 ATG3 ATG4A ATG4B ATG7 BNIP3 BRD3 CASP8 CCSER2 CLTA DBI DBN1 DNMT3B EED EPS8 FAM134A FAM65A FUNDC1 FYCO1 GABARAPL2 GORASP2 KBTBD7 KLHL5 KXD1 LUC7L2 MKRN1 MRFAP1 MYBL2 NHP2L1 RAD1 RAP1GAP RPLP1 SAFB SHFM1 SMARCB1 SPAG9 SQSTM1 TAF7 TAX1BP1 TBC1D17 TBC1D25 TBC1D9 TBC1D9B THAP7 TMOD3 TNIP1 UPF2	15 interactors: C14orf93 C3orf62 C8orf33 DCDC2 GOLGA8F GOLGA8G HTT MAP1LC3B MORF4L1 MORF4L2 MRFAP1L1 PAM16 SUV39H2 TK1 ZDHHC17
Entrez ID		81631	93621
HPRD ID		14358	17589
Ensembl ID		ENSG00000140941	ENSG00000179010
Uniprot IDs		H6UMI0 Q658J6 Q9GZQ8	B3KQA0 Q9Y605
PDB IDs		1V49 2LUE 2ZJD 3VTU 3VTV 3VTW
Enriched GO Terms of Interacting Partners?		Autophagy Mitochondrion Degradation Organelle Disassembly Nucleophagy Cellular Response To Nitrogen Starvation Macroautophagy Regulation Of Organelle Organization Cellular Response To Starvation Positive Regulation Of Metabolic Process Organelle Organization Positive Regulation Of Autophagy Response To Starvation Cellular Response To Nutrient Levels Autophagic Vacuole Assembly Cellular Response To Extracellular Stimulus Cellular Response To Stress Intracellular Transport Catabolic Process Mitochondrion Organization Regulation Of Cellular Component Organization C-terminal Protein Lipidation Protein Delipidation Membrane Organization Response To Stress Vacuole Organization Regulation Of Autophagy Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Complex Disassembly Establishment Of Localization In Cell Regulation Of Histone Modification Actin Filament Capping Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Hydrolase Activity Cellular Localization Negative Regulation Of Actin Filament Depolymerization Response To Nutrient Levels Cellular Component Assembly Protein Localization Regulation Of Ras Protein Signal Transduction Response To Extracellular Stimulus Response To Cobalt Ion Protein Targeting To Membrane Regulation Of Actin Filament Depolymerization Organelle Assembly Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Macroautophagy Negative Regulation Of Histone Acetylation	Visual Learning Visual Behavior Organelle Organization Mitochondrion Organization Neural Plate Formation Fetal Process Involved In Parturition Associative Learning Response To Nutrient Levels Response To Stress Response To Extracellular Stimulus Serotonin Uptake Skeletal Muscle Cell Proliferation Lactate Biosynthetic Process From Pyruvate Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Regulation Of Protein Phosphatase Type 2A Activity Chromatin Modification Learning Response To Stimulus Regulation Of Growth Mitochondrial Transport Protein Import Quinolinate Biosynthetic Process Negative Regulation Of Synaptic Transmission, Dopaminergic Cellular Response To Stress Histone H3-K9 Dimethylation Lactate Biosynthetic Process Response To Toxic Substance Chromatin Organization Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Response To Cortisol Thymidine Metabolic Process Paraxial Mesoderm Formation Quinolinate Metabolic Process Cellular Response To CGMP Cellular Response To Stimulus Deoxyribonucleoside Monophosphate Biosynthetic Process Response To CGMP Protein Import Into Mitochondrial Matrix Serotonin Transport Negative Regulation Of ATPase Activity Sperm Ejaculation Neural Plate Morphogenesis L-glutamate Import Biosynthetic Process Histone H3-K9 Trimethylation Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Peptidyl-lysine Dimethylation Peptidyl-lysine Modification
Tagcloud ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask	actb arfgap2 arl1 bestkeeper bmi1 casc3 cynomolgus ddx3x gapdh genorm lists monkey morf4 normalization normfinder ormdl1 prerequisite reference ribosylation rps19 rsl24d1 sar1a traditionally transcriptome usp22 vitally ywhaz zc3h11a zranb2
Tagcloud (Difference) ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask	actb arfgap2 arl1 bestkeeper bmi1 casc3 cynomolgus ddx3x gapdh genorm lists monkey morf4 normalization normfinder ormdl1 prerequisite reference ribosylation rps19 rsl24d1 sar1a traditionally transcriptome usp22 vitally ywhaz zc3h11a zranb2
Tagcloud (Intersection) ?