MRFAP1 and DCDC2

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid)

		MRFAP1	DCDC2
Name		Morf4 family associated protein 1	doublecortin domain containing 2
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Perinuclear Region Of Cytoplasm	Cytoplasm Microtubule Organizing Center Cytoskeleton Microtubule Cilium Axoneme Cell Projection Kinocilium
	Molecular Function	Protein Binding	Protein Binding Kinesin Binding
	Biological Process	None	Neuron Migration Cellular Defense Response Nervous System Development Sensory Perception Of Sound Cell Projection Organization Regulation Of Wnt Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Smoothened Signaling Pathway Dendrite Morphogenesis Cilium Assembly Regulation Of Cilium Assembly
GWAS		No GWAS studies recorded	Airflow obstruction ( 22837378 ) Estimated glomerular filtration rate ( 31015462 31152163 ) General cognitive ability ( 29844566 ) Information processing speed ( 21130836 ) Uric acid levels ( 21294900 )
Interacting Genes		40 interacting genes: ABI1 ABI2 ABI3 BRK1 C3orf62 C8orf33 CAVIN3 CCDC146 DCDC2 DNAJB5 DPY30 FCHSD2 GOLGA8F GOLGA8G HTT KIFC3 MAP1LC3B MORF4L1 MORF4L2 MTIF3 PAM16 PCBD2 PCNT PRAP1 PRKAA2 SDCBP SH2D4A SMU1 SUV39H2 TEX11 TK1 TPM2 TRIM47 TXN TXN2 UBTD1 UQCC2 WASHC1 ZDHHC17 ZNF655	19 interacting genes: APP B3GNT5 CENPO CKS1B COMMD9 DYNC2LI1 FAM118A KRTAP5-9 KRTAP9-3 LMO3 MICALL2 MRFAP1 NIF3L1 NMU POP5 PTPRCAP SLC38A2 TOLLIP ZNF432
Entrez ID		93621	51473
HPRD ID		17589	09308
Ensembl ID		ENSG00000179010	ENSG00000146038
Uniprot IDs		B3KQA0 Q9Y605	Q9UHG0
PDB IDs		Not available	2DNF
GO Terms Enriched among Interactors		SCAR Complex Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin-based Cell Projection Regulation Of Actin Nucleation Positive Regulation Of Actin Nucleation Regulation Of Cell Projection Assembly Regulation Of Lamellipodium Assembly Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Organelle Organization Regulation Of Lamellipodium Organization Regulation Of Organelle Organization Regulation Of Organelle Assembly Cytoskeleton Actin Filament Organization Neuron Migration Cell Projection Morphogenesis Centriole Filopodium Tip Signaling Adaptor Activity Autophagosome Lamellipodium	None