MAP1LC3B and MYBL2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		MAP1LC3B	MYBL2
Gene Name		microtubule-associated protein 1 light chain 3 beta	v-myb avian myeloblastosis viral oncogene homolog-like 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Pre-autophagosomal Structure Autophagic Vacuole Membrane Intracellular Autophagic Vacuole Cytosol Microtubule Axoneme Endomembrane System Extrinsic Component Of Membrane Organelle Membrane Cytoplasmic Vesicle	Nucleoplasm Myb Complex
	Molecular Function	Protein Binding Microtubule Binding GABA Receptor Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation Cellular Response To Nitrogen Starvation Nucleophagy Membrane Fusion	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Cycle Mitotic Spindle Assembly
Pathways			G2/M Transition G0 and Early G1 Mitotic G2-G2/M phases Mitotic G1-G1/S phases Polo-like kinase mediated events Cell Cycle, Mitotic
Drugs
Diseases
GWAS		Major depressive disorder ( 22472876)
Protein-Protein Interactions		50 interactors: AAMP ADD1 ADNP ARFGAP1 ATG3 ATG4A ATG4B ATG7 BNIP3 BRD3 CASP8 CCSER2 CLTA DBI DBN1 DNMT3B EED EPS8 FAM134A FAM65A FUNDC1 FYCO1 GABARAPL2 GORASP2 KBTBD7 KLHL5 KXD1 LUC7L2 MKRN1 MRFAP1 MYBL2 NHP2L1 RAD1 RAP1GAP RPLP1 SAFB SHFM1 SMARCB1 SPAG9 SQSTM1 TAF7 TAX1BP1 TBC1D17 TBC1D25 TBC1D9 TBC1D9B THAP7 TMOD3 TNIP1 UPF2	28 interactors: CCNA1 CCNA2 CCND1 CCNE1 CDC34 CDK2 CDK9 CREBBP CXCR4 E2F1 E2F3 EP300 LIN9 LZTR1 MAP1LC3B MAPK6 NCOR1 NCOR2 PARP1 RBL1 SKP2 SND1 TRIM15 TTF2 UBB UBE2D4 ZBTB9 ZNF622
Entrez ID		81631	4605
HPRD ID		14358	03247
Ensembl ID		ENSG00000140941	ENSG00000101057
Uniprot IDs		H6UMI0 Q658J6 Q9GZQ8	B7Z8D9 F8W6N6 P10244
PDB IDs		1V49 2LUE 2ZJD 3VTU 3VTV 3VTW
Enriched GO Terms of Interacting Partners?		Autophagy Mitochondrion Degradation Organelle Disassembly Nucleophagy Cellular Response To Nitrogen Starvation Macroautophagy Regulation Of Organelle Organization Cellular Response To Starvation Positive Regulation Of Metabolic Process Organelle Organization Positive Regulation Of Autophagy Response To Starvation Cellular Response To Nutrient Levels Autophagic Vacuole Assembly Cellular Response To Extracellular Stimulus Cellular Response To Stress Intracellular Transport Catabolic Process Mitochondrion Organization Regulation Of Cellular Component Organization C-terminal Protein Lipidation Protein Delipidation Membrane Organization Response To Stress Vacuole Organization Regulation Of Autophagy Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Complex Disassembly Establishment Of Localization In Cell Regulation Of Histone Modification Actin Filament Capping Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Hydrolase Activity Cellular Localization Negative Regulation Of Actin Filament Depolymerization Response To Nutrient Levels Cellular Component Assembly Protein Localization Regulation Of Ras Protein Signal Transduction Response To Extracellular Stimulus Response To Cobalt Ion Protein Targeting To Membrane Regulation Of Actin Filament Depolymerization Organelle Assembly Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Macroautophagy Negative Regulation Of Histone Acetylation	Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Notch Signaling Pathway Cell Cycle G1/S Transition Of Mitotic Cell Cycle Transcription Initiation From RNA Polymerase II Promoter G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Process DNA-templated Transcription, Initiation Regulation Of Cell Cycle Cell Cycle Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Transcription, DNA-templated Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle Phase Transition Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Response To Stress RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process
Tagcloud ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask	12q 12q21 14q31 15q25 16q23 18p 19q13 20p12 20pq 20q12 21q21 3p14 4pq 5p14 5q14 6p12 7p12 8q23 cardia cdkn2 fist gej mlvi2 mts1 nrasl3 parentheses ptpn1 rca1 xpq xq25
Tagcloud (Difference) ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask	12q 12q21 14q31 15q25 16q23 18p 19q13 20p12 20pq 20q12 21q21 3p14 4pq 5p14 5q14 6p12 7p12 8q23 cardia cdkn2 fist gej mlvi2 mts1 nrasl3 parentheses ptpn1 rca1 xpq xq25
Tagcloud (Intersection) ?