MAP1LC3B and NHP2L1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		MAP1LC3B	NHP2L1
Gene Name		microtubule-associated protein 1 light chain 3 beta	NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
Image
Gene Ontology Annotations	Cellular Component	Pre-autophagosomal Structure Autophagic Vacuole Membrane Intracellular Autophagic Vacuole Cytosol Microtubule Axoneme Endomembrane System Extrinsic Component Of Membrane Organelle Membrane Cytoplasmic Vesicle	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Box C/D SnoRNP Complex Protein Complex
	Molecular Function	Protein Binding Microtubule Binding GABA Receptor Binding	RNA Binding Protein Binding SnoRNA Binding Poly(A) RNA Binding
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation Cellular Response To Nitrogen Starvation Nucleophagy Membrane Fusion	MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression Ribosome Biogenesis
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Major depressive disorder ( 22472876)
Protein-Protein Interactions		50 interactors: AAMP ADD1 ADNP ARFGAP1 ATG3 ATG4A ATG4B ATG7 BNIP3 BRD3 CASP8 CCSER2 CLTA DBI DBN1 DNMT3B EED EPS8 FAM134A FAM65A FUNDC1 FYCO1 GABARAPL2 GORASP2 KBTBD7 KLHL5 KXD1 LUC7L2 MKRN1 MRFAP1 MYBL2 NHP2L1 RAD1 RAP1GAP RPLP1 SAFB SHFM1 SMARCB1 SPAG9 SQSTM1 TAF7 TAX1BP1 TBC1D17 TBC1D25 TBC1D9 TBC1D9B THAP7 TMOD3 TNIP1 UPF2	14 interactors: CDKN2C CHST1 GTF3C1 LRIF1 MAP1LC3B POLA2 PPIH PRPF3 PRPF31 PRPF4 RAD17 RBM10 SNW1 XRCC6
Entrez ID		81631	4809
HPRD ID		14358	03197
Ensembl ID		ENSG00000140941	ENSG00000100138
Uniprot IDs		H6UMI0 Q658J6 Q9GZQ8	P55769 Q6FHM6
PDB IDs		1V49 2LUE 2ZJD 3VTU 3VTV 3VTW	1E7K 2JNB 2OZB 3SIU 3SIV
Enriched GO Terms of Interacting Partners?		Autophagy Mitochondrion Degradation Organelle Disassembly Nucleophagy Cellular Response To Nitrogen Starvation Macroautophagy Regulation Of Organelle Organization Cellular Response To Starvation Positive Regulation Of Metabolic Process Organelle Organization Positive Regulation Of Autophagy Response To Starvation Cellular Response To Nutrient Levels Autophagic Vacuole Assembly Cellular Response To Extracellular Stimulus Cellular Response To Stress Intracellular Transport Catabolic Process Mitochondrion Organization Regulation Of Cellular Component Organization C-terminal Protein Lipidation Protein Delipidation Membrane Organization Response To Stress Vacuole Organization Regulation Of Autophagy Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Complex Disassembly Establishment Of Localization In Cell Regulation Of Histone Modification Actin Filament Capping Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Hydrolase Activity Cellular Localization Negative Regulation Of Actin Filament Depolymerization Response To Nutrient Levels Cellular Component Assembly Protein Localization Regulation Of Ras Protein Signal Transduction Response To Extracellular Stimulus Response To Cobalt Ion Protein Targeting To Membrane Regulation Of Actin Filament Depolymerization Organelle Assembly Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Macroautophagy Negative Regulation Of Histone Acetylation	RNA Splicing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Spliceosomal Tri-snRNP Complex Assembly RNA Metabolic Process Gene Expression Cellular Metabolic Process Spliceosomal SnRNP Assembly Positive Regulation Of Viral Process Telomere Maintenance Positive Regulation Of Vitamin D Receptor Signaling Pathway Cellular Hyperosmotic Salinity Response Macromolecule Biosynthetic Process 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter Cellular Response To X-ray Regulation Of Vitamin D Receptor Signaling Pathway Regulation Of Viral Process G1/S Transition Of Mitotic Cell Cycle TRNA Transcription Ribonucleoprotein Complex Assembly Establishment Of Integrated Proviral Latency Metabolic Process Cellular Hyperosmotic Response Hyperosmotic Salinity Response Establishment Of Viral Latency Positive Regulation By Host Of Viral Transcription Mitotic Cell Cycle Process DNA Replication Checkpoint Cellular Response To Salt Stress DNA Recombination Mitotic Cell Cycle DNA Ligation
Tagcloud ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask
Tagcloud (Difference) ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask
Tagcloud (Intersection) ?