MAP1LC3B and KBTBD7

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		MAP1LC3B	KBTBD7
Description		microtubule associated protein 1 light chain 3 beta	kelch repeat and BTB domain containing 7
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Cytoplasm Mitochondrion Autophagosome Cytosol Cytoskeleton Microtubule Axoneme Endomembrane System Membrane Organelle Membrane Cytoplasmic Vesicle Mitochondrial Membrane	Nucleus Cytoplasm Cytosol Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding Ceramide Binding	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Mitophagy Autophagy Cellular Response To Nitrogen Starvation Cellular Response To Starvation Macroautophagy Autophagosome Maturation	Negative Regulation Of Signal Transduction Protein Ubiquitination Regulation Of Rac Protein Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination
Pathways		Macroautophagy PINK1-PRKN Mediated Mitophagy TBC/RABGAPs Receptor Mediated Mitophagy Pexophagy Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex SARS-CoV-2 modulates autophagy KEAP1-NFE2L2 pathway	Regulation of RAS by GAPs Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		General factor of neuroticism ( 30867560) Major depressive disorder ( 22472876) Metabolite levels ( 23823483) Neuroticism ( 29255261) Refractive error ( 32231278)
Interacting Genes		97 interacting genes: AAMP ABTB3 ADD1 ADNP AFTPH AMBRA1 ANK2 APPL1 ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4C ATG4D ATG7 BAG6 BIRC6 BNIP3 BRD3 BRD9 CAMSAP1 CARS2 CASP8 CCDC50 CCPG1 CCSER2 CDC37 CLTA CUL3 DBI DBN1 DNMT3B DPPA4 EED EPS8 EVA1A FLCN FUNDC1 GORASP2 HYPK IRGQ KBTBD7 KLHL5 KXD1 LUC7L2 MESD MKRN1 MRFAP1 MRTFA MTX1 MYBL2 NCOR1 NEDD4 NEK9 OPTN PCNT PLEKHM1 PRKCZ PRUNE2 RAD1 RAP1GAP RASAL3 RETREG1 RETREG2 RIC1 RIPOR1 RPLP1 SAMM50 SEM1 SEPTIN3 SMARCB1 SNCA SNU13 SNX18 SPAG9 SQSTM1 STK3 STK36 TAF7 TBC1D17 TBC1D25 TBC1D5 TBC1D9 TBC1D9B THAP7 TMOD3 TNIP1 TPPP TRIM21 TRIM25 TRIM32 TTN UPF2 USP10 VHL WDR90	20 interacting genes: BARD1 BLMH C8orf33 CCDC106 CPT1A DRD2 DUSP23 GABARAP GABARAPL1 GABARAPL2 HAP1 KLF15 LRIF1 MAP1LC3B MAP1LC3C MEOX2 NFKBIE PHC2 PSME3 VANGL2
Entrez ID		81631	84078
HPRD ID		14358	13759
Ensembl ID		ENSG00000140941	ENSG00000120696
Uniprot IDs		Q658J6 Q9GZQ8	Q8WVZ9
PDB IDs		1V49 2LUE 2N9X 2ZJD 3VTU 3VTV 3VTW 3WAO 3X0W 4WAA 5D94 5DCN 5GMV 5MS2 5MS5 5MS6 5V4K 5W9A 5XAC 5XAD 5XAE 6J04 6LAN 7ELG 7GA8 7GA9 7GAA 7GAB 7GAC 7GAD 7GAE 7GAF 7GAG 7GAH 7GAI 7GAJ 7GAK 7GAL 7GAM 7GAN 7GAO 7GAP 7GAQ 7GAR 7GAS 7GAU 8Q53 8Q7K 8YV6
Enriched GO Terms of Interacting Partners?		Autophagy Autophagy Of Mitochondrion Mitophagy Macroautophagy Autophagosome Autophagosome Assembly Autophagosome Organization Nucleophagy Organelle Organization Regulation Of Autophagy Vacuole Organization Organelle Assembly Piecemeal Microautophagy Of The Nucleus Protein-phosphatidylethanolamide Deconjugating Activity Microautophagy Catabolic Process Positive Regulation Of Autophagy Protein Delipidation Aggrephagy Cellular Component Assembly Establishment Of Protein Localization Cytoplasm Substrate Localization To Autophagosome Intracellular Protein Localization Protein Transport Protein Binding Positive Regulation Of Catabolic Process Cytosol Endoplasmic Reticulum-autophagosome Adaptor Activity Cellular Localization Establishment Of Localization In Cell Regulation Of Protein Stability Proteolysis Involved In Protein Catabolic Process Cysteine-type Endopeptidase Activity Regulation Of Cellular Component Organization Response To Mitochondrial Depolarisation Proteolysis Regulation Of Organelle Organization Regulation Of Macroautophagy Protein Monoubiquitination GTPase Activator Activity Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Positive Regulation Of Macroautophagy Phagophore Assembly Site Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein Catabolic Process Regulation Of Cell Projection Assembly	Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Autophagosome Autophagosome Maturation Autophagosome Membrane Mitophagy Autophagy Of Mitochondrion Autophagy Autophagosome Assembly Autophagosome Organization Phospholipid Binding Protein-containing Complex Disassembly GABA Receptor Binding Macroautophagy Vacuole Organization Cellular Response To Starvation Response To Starvation Cellular Response To Nutrient Levels Organelle Assembly Response To Nutrient Levels Beta-tubulin Binding Ubiquitin Protein Ligase Binding Catabolic Process Cytoplasmic Vesicle Microtubule Regulation Of Synaptic Transmission, GABAergic Regulation Of Protein Catabolic Process Negative Regulation Of MRNA 3'-end Processing Positive Regulation Of Neurotrophin Production Response To Stress Organelle Membrane Long-chain Fatty Acid Transport
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