MRFAP1 and MORF4L1

Number of citations of the paper that reports this interaction (PMID 12397079)
33

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		MRFAP1	MORF4L1
Gene Name		Morf4 family associated protein 1	mortality factor 4 like 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Perinuclear Region Of Cytoplasm	Nucleoplasm Sin3 Complex NuA4 Histone Acetyltransferase Complex
	Molecular Function	Protein Binding	Chromatin Binding Protein Binding Protein N-terminus Binding
	Biological Process		Double-strand Break Repair Via Homologous Recombination Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Proliferation Histone Deacetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation
Pathways			Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS			Coronary heart disease ( 21378988)
Protein-Protein Interactions		15 interactors: C14orf93 C3orf62 C8orf33 DCDC2 GOLGA8F GOLGA8G HTT MAP1LC3B MORF4L1 MORF4L2 MRFAP1L1 PAM16 SUV39H2 TK1 ZDHHC17	35 interactors: APP ARRDC3 BEND7 CALM1 CAMK2B CEP57L1 FAM9B FXR2 GMCL1 GOLGA2 HINFP HIST3H3 HMBOX1 IKZF1 L3MBTL3 LZTS2 MEOX1 MRFAP1 MRFAP1L1 MRGBP MSL1 NAB2 NAV2 PBXIP1 PHF12 RACGAP1 RB1 REL TFCP2 THAP1 TNIP1 TNNT1 TRIM41 ZBTB10 ZBTB9
Entrez ID		93621	10933
HPRD ID		17589	09532
Ensembl ID		ENSG00000179010	ENSG00000185787
Uniprot IDs		B3KQA0 Q9Y605	B3KTM8 Q9UBU8
PDB IDs			2AQL 2EFI 2F5J 2F5K 2LKM
Enriched GO Terms of Interacting Partners?		Visual Learning Visual Behavior Organelle Organization Mitochondrion Organization Neural Plate Formation Fetal Process Involved In Parturition Associative Learning Response To Nutrient Levels Response To Stress Response To Extracellular Stimulus Serotonin Uptake Skeletal Muscle Cell Proliferation Lactate Biosynthetic Process From Pyruvate Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Regulation Of Protein Phosphatase Type 2A Activity Chromatin Modification Learning Response To Stimulus Regulation Of Growth Mitochondrial Transport Protein Import Quinolinate Biosynthetic Process Negative Regulation Of Synaptic Transmission, Dopaminergic Cellular Response To Stress Histone H3-K9 Dimethylation Lactate Biosynthetic Process Response To Toxic Substance Chromatin Organization Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Response To Cortisol Thymidine Metabolic Process Paraxial Mesoderm Formation Quinolinate Metabolic Process Cellular Response To CGMP Cellular Response To Stimulus Deoxyribonucleoside Monophosphate Biosynthetic Process Response To CGMP Protein Import Into Mitochondrial Matrix Serotonin Transport Negative Regulation Of ATPase Activity Sperm Ejaculation Neural Plate Morphogenesis L-glutamate Import Biosynthetic Process Histone H3-K9 Trimethylation Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Peptidyl-lysine Dimethylation Peptidyl-lysine Modification	Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Gene Expression RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Spindle Midzone Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cell Cycle Process Positive Regulation Of Transcription, DNA-templated Cell Cycle Immune System Process Multicellular Organismal Development Regulation Of Cell Division Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Cycle Process Biosynthetic Process Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cell Division Neuron Maturation Cell Maturation Chromatin Modification Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Neutrophil Differentiation Cytokinesis, Initiation Of Separation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade
Tagcloud ?		actb arfgap2 arl1 bestkeeper bmi1 casc3 cynomolgus ddx3x gapdh genorm lists monkey morf4 normalization normfinder ormdl1 prerequisite reference ribosylation rps19 rsl24d1 sar1a traditionally transcriptome usp22 vitally ywhaz zc3h11a zranb2	aligned backgrounds balance chromodomain controlling e3 elegans ensure fate finger germ glp homologue ligases likewise mrg mrg15 notch overproliferation proliferative proper proteasome rfp sensitized spatially stem suppresses threshold tightly
Tagcloud (Difference) ?		actb arfgap2 arl1 bestkeeper bmi1 casc3 cynomolgus ddx3x gapdh genorm lists monkey morf4 normalization normfinder ormdl1 prerequisite reference ribosylation rps19 rsl24d1 sar1a traditionally transcriptome usp22 vitally ywhaz zc3h11a zranb2	aligned backgrounds balance chromodomain controlling e3 elegans ensure fate finger germ glp homologue ligases likewise mrg mrg15 notch overproliferation proliferative proper proteasome rfp sensitized spatially stem suppresses threshold tightly
Tagcloud (Intersection) ?