MRFAP1 and CAVIN3

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		MRFAP1	CAVIN3
Description		Morf4 family associated protein 1	caveolae associated protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Perinuclear Region Of Cytoplasm	Cytoplasm Cytosol Caveola Membrane Protein-containing Complex
	Molecular Function	Protein Binding	Protein Kinase C Binding Protein Binding
	Biological Process		Cortical Actin Cytoskeleton Organization Circadian Regulation Of Gene Expression Rhythmic Process Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Fermentation
Pathways
Drugs
Diseases
GWAS			Rheumatic heart disease ( 34106200)
Interacting Genes		40 interacting genes: ABI1 ABI2 ABI3 BRK1 C3orf62 C8orf33 CAVIN3 CCDC146 DCDC2 DNAJB5 DPY30 FCHSD2 GOLGA8F GOLGA8G HTT KIFC3 MAP1LC3B MORF4L1 MORF4L2 MTIF3 PAM16 PCBD2 PCNT PRAP1 PRKAA2 SDCBP SH2D4A SMU1 SUV39H2 TEX11 TK1 TPM2 TRIM47 TXN TXN2 UBTD1 UQCC2 WASHC1 ZDHHC17 ZNF655	12 interacting genes: BRCA1 CEP70 CEP76 GOLGA6L9 GPRASP2 MAGEA11 MRFAP1 NUP62 TFIP11 TIMM8A TPM3 UBC
Entrez ID		93621	112464
HPRD ID		17589	17908
Ensembl ID		ENSG00000179010	ENSG00000170955
Uniprot IDs		B3KQA0 Q9Y605	Q969G5
PDB IDs
Enriched GO Terms of Interacting Partners?		SCAR Complex Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin-based Cell Projection Regulation Of Actin Nucleation Positive Regulation Of Actin Nucleation Regulation Of Cell Projection Assembly Regulation Of Lamellipodium Assembly Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Organelle Organization Regulation Of Lamellipodium Organization Regulation Of Organelle Organization Regulation Of Organelle Assembly Cytoskeleton Actin Filament Organization Neuron Migration Cell Projection Morphogenesis Centriole Filopodium Tip Signaling Adaptor Activity Autophagosome Lamellipodium	Regulation Of Centriole Replication Regulation Of Centrosome Duplication Regulation Of Centrosome Cycle Regulation Of Microtubule-based Process
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