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MAP1LC3B and RAD1
Number of citations of the paper that reports this interaction (PubMedID
33545068
)
0
Data Source:
BioGRID
(proximity labelling technology)
HPRD
(two hybrid)
MAP1LC3B
RAD1
Description
microtubule associated protein 1 light chain 3 beta
RAD1 checkpoint DNA exonuclease
Image
GO Annotations
Cellular Component
Autophagosome Membrane
Cytoplasm
Mitochondrion
Autophagosome
Cytosol
Cytoskeleton
Microtubule
Axoneme
Endomembrane System
Membrane
Organelle Membrane
Cytoplasmic Vesicle
Mitochondrial Membrane
Nucleus
Nucleoplasm
Chromosome
Checkpoint Clamp Complex
Molecular Function
Protein Binding
Phospholipid Binding
Microtubule Binding
Phosphatidylethanolamine Binding
Ubiquitin Protein Ligase Binding
Ceramide Binding
Damaged DNA Binding
Protein Binding
Double-stranded DNA 3'-5' DNA Exonuclease Activity
Biological Process
Autophagosome Assembly
Autophagy Of Mitochondrion
Mitophagy
Autophagy
Cellular Response To Nitrogen Starvation
Cellular Response To Starvation
Macroautophagy
Autophagosome Maturation
DNA Damage Checkpoint Signaling
DNA Repair
DNA Damage Response
Substantia Nigra Development
Meiotic Recombination Checkpoint Signaling
Cellular Response To Ionizing Radiation
Pathways
Macroautophagy
PINK1-PRKN Mediated Mitophagy
TBC/RABGAPs
Receptor Mediated Mitophagy
Pexophagy
Translation of Replicase and Assembly of the Replication Transcription Complex
Translation of Replicase and Assembly of the Replication Transcription Complex
SARS-CoV-2 modulates autophagy
KEAP1-NFE2L2 pathway
Activation of ATR in response to replication stress
HDR through Single Strand Annealing (SSA)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Regulation of TP53 Activity through Phosphorylation
G2/M DNA damage checkpoint
Impaired BRCA2 binding to RAD51
Drugs
Diseases
GWAS
General factor of neuroticism (
30867560
)
Major depressive disorder (
22472876
)
Metabolite levels (
23823483
)
Neuroticism (
29255261
)
Refractive error (
32231278
)
Daytime sleep phenotypes (
27126917
)
Interacting Genes
97 interacting genes:
AAMP
ABTB3
ADD1
ADNP
AFTPH
AMBRA1
ANK2
APPL1
ARFGAP1
ATG13
ATG3
ATG4A
ATG4B
ATG4C
ATG4D
ATG7
BAG6
BIRC6
BNIP3
BRD3
BRD9
CAMSAP1
CARS2
CASP8
CCDC50
CCPG1
CCSER2
CDC37
CLTA
CUL3
DBI
DBN1
DNMT3B
DPPA4
EED
EPS8
EVA1A
FLCN
FUNDC1
GORASP2
HYPK
IRGQ
KBTBD7
KLHL5
KXD1
LUC7L2
MESD
MKRN1
MRFAP1
MRTFA
MTX1
MYBL2
NCOR1
NEDD4
NEK9
OPTN
PCNT
PLEKHM1
PRKCZ
PRUNE2
RAD1
RAP1GAP
RASAL3
RETREG1
RETREG2
RIC1
RIPOR1
RPLP1
SAMM50
SEM1
SEPTIN3
SMARCB1
SNCA
SNU13
SNX18
SPAG9
SQSTM1
STK3
STK36
TAF7
TBC1D17
TBC1D25
TBC1D5
TBC1D9
TBC1D9B
THAP7
TMOD3
TNIP1
TPPP
TRIM21
TRIM25
TRIM32
TTN
UPF2
USP10
VHL
WDR90
24 interacting genes:
COPS5
CSNK2A1
CSNK2A2
DNAJC7
FEN1
HUS1
HUS1B
MAP1LC3B
MSH2
MSH3
MSH6
NEIL1
OGG1
POLB
PRKN
RAD17
RAD9B
RHNO1
RPA1
RPA2
SIRT6
TDG
TOPBP1
WRN
Entrez ID
81631
5810
HPRD ID
14358
04400
Ensembl ID
ENSG00000140941
ENSG00000113456
Uniprot IDs
Q658J6
Q9GZQ8
O60671
PDB IDs
1V49
2LUE
2N9X
2ZJD
3VTU
3VTV
3VTW
3WAO
3X0W
4WAA
5D94
5DCN
5GMV
5MS2
5MS5
5MS6
5V4K
5W9A
5XAC
5XAD
5XAE
6J04
6LAN
7ELG
7GA8
7GA9
7GAA
7GAB
7GAC
7GAD
7GAE
7GAF
7GAG
7GAH
7GAI
7GAJ
7GAK
7GAL
7GAM
7GAN
7GAO
7GAP
7GAQ
7GAR
7GAS
7GAU
8Q53
8Q7K
8YV6
3A1J
3G65
3GGR
6J8Y
7Z6H
8GNN
8WU8
Enriched GO Terms of Interacting Partners
?
Autophagy
Autophagy Of Mitochondrion
Mitophagy
Macroautophagy
Autophagosome
Autophagosome Assembly
Autophagosome Organization
Nucleophagy
Organelle Organization
Regulation Of Autophagy
Vacuole Organization
Organelle Assembly
Piecemeal Microautophagy Of The Nucleus
Protein-phosphatidylethanolamide Deconjugating Activity
Microautophagy
Catabolic Process
Positive Regulation Of Autophagy
Protein Delipidation
Aggrephagy
Cellular Component Assembly
Establishment Of Protein Localization
Cytoplasm
Substrate Localization To Autophagosome
Intracellular Protein Localization
Protein Transport
Protein Binding
Positive Regulation Of Catabolic Process
Cytosol
Endoplasmic Reticulum-autophagosome Adaptor Activity
Cellular Localization
Establishment Of Localization In Cell
Regulation Of Protein Stability
Proteolysis Involved In Protein Catabolic Process
Cysteine-type Endopeptidase Activity
Regulation Of Cellular Component Organization
Response To Mitochondrial Depolarisation
Proteolysis
Regulation Of Organelle Organization
Regulation Of Macroautophagy
Protein Monoubiquitination
GTPase Activator Activity
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Positive Regulation Of Macroautophagy
Phagophore Assembly Site
Protein Polyubiquitination
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Protein Catabolic Process
Regulation Of Cell Projection Assembly
DNA Repair
DNA Metabolic Process
DNA Damage Response
Cellular Response To Stress
Base-excision Repair
Double-strand Break Repair
Damaged DNA Binding
DNA Recombination
Nucleic Acid Metabolic Process
DNA Damage Checkpoint Signaling
Response To Stress
Recombinational Repair
Nucleobase-containing Compound Metabolic Process
Signal Transduction In Response To DNA Damage
Site Of Double-strand Break
Protein Localization To Site Of Double-strand Break
Mismatch Repair
Mitotic DNA Damage Checkpoint Signaling
Response To Radiation
Mitotic DNA Integrity Checkpoint Signaling
Double-strand Break Repair Via Homologous Recombination
Negative Regulation Of Cell Cycle Phase Transition
Chromosome Organization
Mitotic Intra-S DNA Damage Checkpoint Signaling
Nucleoplasm
DNA Replication Checkpoint Signaling
Negative Regulation Of Cell Cycle Process
Oxidized Purine DNA Binding
Protein Localization To Chromosome
Macromolecule Metabolic Process
Negative Regulation Of Cell Cycle
Mitotic DNA Replication Checkpoint Signaling
Response To Ionizing Radiation
Mismatched DNA Binding
Regulation Of Cell Cycle Process
Response To UV
Single Guanine Insertion Binding
Chromosome, Telomeric Region
Regulation Of Cell Cycle
Regulation Of Cell Cycle Phase Transition
Telomere Maintenance
Chromatin-protein Adaptor Activity
Guanine/thymine Mispair Binding
Nucleotide-excision Repair
Regulation Of DNA Metabolic Process
Negative Regulation Of Mitotic Cell Cycle
Telomere Organization
Checkpoint Clamp Complex
Negative Regulation Of DNA Metabolic Process
Regulation Of DNA Recombination
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Tagcloud (Difference)
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Tagcloud (Intersection)
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