MAP1LC3B and DBI

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		MAP1LC3B	DBI
Gene Name		microtubule-associated protein 1 light chain 3 beta	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
Image
Gene Ontology Annotations	Cellular Component	Pre-autophagosomal Structure Autophagic Vacuole Membrane Intracellular Autophagic Vacuole Cytosol Microtubule Axoneme Endomembrane System Extrinsic Component Of Membrane Organelle Membrane Cytoplasmic Vesicle	Mitochondrion Endoplasmic Reticulum Golgi Apparatus Extracellular Vesicular Exosome Perinuclear Endoplasmic Reticulum
	Molecular Function	Protein Binding Microtubule Binding GABA Receptor Binding	Lipid Binding Benzodiazepine Receptor Binding Long-chain Fatty Acyl-CoA Binding Protein Dimerization Activity
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation Cellular Response To Nitrogen Starvation Nucleophagy Membrane Fusion	Behavioral Fear Response Hair Follicle Development Triglyceride Metabolic Process Transport Learning Or Memory Protein Palmitoylation Lateral Ventricle Development Phosphatidylcholine Acyl-chain Remodeling Long-term Synaptic Potentiation
Pathways
Drugs
Diseases
GWAS		Major depressive disorder ( 22472876)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		50 interactors: AAMP ADD1 ADNP ARFGAP1 ATG3 ATG4A ATG4B ATG7 BNIP3 BRD3 CASP8 CCSER2 CLTA DBI DBN1 DNMT3B EED EPS8 FAM134A FAM65A FUNDC1 FYCO1 GABARAPL2 GORASP2 KBTBD7 KLHL5 KXD1 LUC7L2 MKRN1 MRFAP1 MYBL2 NHP2L1 RAD1 RAP1GAP RPLP1 SAFB SHFM1 SMARCB1 SPAG9 SQSTM1 TAF7 TAX1BP1 TBC1D17 TBC1D25 TBC1D9 TBC1D9B THAP7 TMOD3 TNIP1 UPF2	10 interactors: DUSP23 GSK3B MAP1LC3B NIPSNAP1 NSFL1C PPCDC RAD23A RAD23B TSPO UBXN2A
Entrez ID		81631	1622
HPRD ID		14358	08832
Ensembl ID		ENSG00000140941	ENSG00000155368
Uniprot IDs		H6UMI0 Q658J6 Q9GZQ8	B8ZWD1 P07108
PDB IDs		1V49 2LUE 2ZJD 3VTU 3VTV 3VTW	2CB8 2FJ9
Enriched GO Terms of Interacting Partners?		Autophagy Mitochondrion Degradation Organelle Disassembly Nucleophagy Cellular Response To Nitrogen Starvation Macroautophagy Regulation Of Organelle Organization Cellular Response To Starvation Positive Regulation Of Metabolic Process Organelle Organization Positive Regulation Of Autophagy Response To Starvation Cellular Response To Nutrient Levels Autophagic Vacuole Assembly Cellular Response To Extracellular Stimulus Cellular Response To Stress Intracellular Transport Catabolic Process Mitochondrion Organization Regulation Of Cellular Component Organization C-terminal Protein Lipidation Protein Delipidation Membrane Organization Response To Stress Vacuole Organization Regulation Of Autophagy Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Complex Disassembly Establishment Of Localization In Cell Regulation Of Histone Modification Actin Filament Capping Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Hydrolase Activity Cellular Localization Negative Regulation Of Actin Filament Depolymerization Response To Nutrient Levels Cellular Component Assembly Protein Localization Regulation Of Ras Protein Signal Transduction Response To Extracellular Stimulus Response To Cobalt Ion Protein Targeting To Membrane Regulation Of Actin Filament Depolymerization Organelle Assembly Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Macroautophagy Negative Regulation Of Histone Acetylation	Cellular Response To Stress Autophagic Vacuole Assembly Macroautophagy Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Vacuole Organization Nuclear Envelope Reassembly Regulation Of Protein Catabolic Process Membrane Fusion Response To Nutrient Levels Cellular Response To Starvation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Extracellular Stimulus Ubiquitin-dependent Protein Catabolic Process Autophagy Modification-dependent Protein Catabolic Process Cellular Response To Nutrient Levels Response To Starvation Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Protein Catabolic Process Cellular Response To Extracellular Stimulus Response To Stress Cellular Macromolecule Catabolic Process Nuclear Envelope Organization Catabolic Process Response To External Stimulus Golgi Organization Nucleotide-excision Repair Negative Regulation Of Type B Pancreatic Cell Development Nucleotide-excision Repair, DNA Damage Recognition Superior Temporal Gyrus Development Organelle Assembly Nucleus Organization Re-entry Into Mitotic Cell Cycle Response To Vitamin B1 Negative Regulation Of Neuron Maturation Hypermethylation Of CpG Island Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Positive Regulation Of Necrotic Cell Death Cellular Response To Interleukin-3 Regulation Of Proteolysis Proteolysis Negative Regulation Of Glycogen (starch) Synthase Activity Regulation Of Neuron Maturation Cellular Metabolic Process Protein Localization To Microtubule Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Dendrite Morphogenesis
Tagcloud ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask	abolishes availability bear box cdna cloned contains dead diminishes display fibroblast identity kb message mitogenic nontransforming notch overexpressed place recognize repeats solely take terminally terminus transcript transform transforming truncated
Tagcloud (Difference) ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask	abolishes availability bear box cdna cloned contains dead diminishes display fibroblast identity kb message mitogenic nontransforming notch overexpressed place recognize repeats solely take terminally terminus transcript transform transforming truncated
Tagcloud (Intersection) ?