MRFAP1 and UQCC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MRFAP1	UQCC2
Description		Morf4 family associated protein 1	ubiquinol-cytochrome c reductase complex assembly factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Perinuclear Region Of Cytoplasm	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Mitochondrial Matrix Membrane Nuclear Body Mitochondrial Nucleoid
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Regulation Of Oxidative Phosphorylation Mitochondrial Respiratory Chain Complex III Assembly Regulation Of Insulin Secretion Positive Regulation Of Mitochondrial Translation Regulation Of Skeletal Muscle Cell Differentiation
Pathways			Complex III assembly
Drugs
Diseases
GWAS			Asthma and attention deficit hyperactivity disorder ( 31619474) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Gait speed in old age ( 28077804) Hodgkin's lymphoma ( 30194254)
Interacting Genes		40 interacting genes: ABI1 ABI2 ABI3 BRK1 C3orf62 C8orf33 CAVIN3 CCDC146 DCDC2 DNAJB5 DPY30 FCHSD2 GOLGA8F GOLGA8G HTT KIFC3 MAP1LC3B MORF4L1 MORF4L2 MTIF3 PAM16 PCBD2 PCNT PRAP1 PRKAA2 SDCBP SH2D4A SMU1 SUV39H2 TEX11 TK1 TPM2 TRIM47 TXN TXN2 UBTD1 UQCC2 WASHC1 ZDHHC17 ZNF655	15 interacting genes: CDKN2D CEACAM5 EXOC8 GNG13 GRB2 HSPB1 MKRN3 MRFAP1 NRDE2 RABGAP1L SNAP25 TRAPPC2 TRAPPC2B TXN2 ZNF765
Entrez ID		93621	84300
HPRD ID		17589	12847
Ensembl ID		ENSG00000179010	ENSG00000137288
Uniprot IDs		B3KQA0 Q9Y605	Q9BRT2
PDB IDs
Enriched GO Terms of Interacting Partners?		SCAR Complex Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin-based Cell Projection Regulation Of Actin Nucleation Positive Regulation Of Actin Nucleation Regulation Of Cell Projection Assembly Regulation Of Lamellipodium Assembly Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Organelle Organization Regulation Of Lamellipodium Organization Regulation Of Organelle Organization Regulation Of Organelle Assembly Cytoskeleton Actin Filament Organization Neuron Migration Cell Projection Morphogenesis Centriole Filopodium Tip Signaling Adaptor Activity Autophagosome Lamellipodium	Vesicle Tethering TRAPPII Protein Complex TRAPPIII Protein Complex TRAPP Complex Vesicle Organization COPII Vesicle Coating Perinuclear Region Of Cytoplasm Vesicle-mediated Transport Vesicle Coating Vesicle Docking Involved In Exocytosis Guanyl-nucleotide Exchange Factor Adaptor Activity Negative Regulation Of Protein Kinase C Signaling
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