MRFAP1 and SMU1

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		MRFAP1	SMU1
Name		Morf4 family associated protein 1	SMU1 DNA replication regulator and spliceosomal factor
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	None	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways		None	mRNA Splicing - Major Pathway
GWAS		No GWAS studies recorded	Aspartate aminotransferase levels ( 33547301 ) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223 )
Interacting Genes		40 interacting genes: ABI1 ABI2 ABI3 BRK1 C3orf62 C8orf33 CAVIN3 CCDC146 DCDC2 DNAJB5 DPY30 FCHSD2 GOLGA8F GOLGA8G HTT KIFC3 MAP1LC3B MORF4L1 MORF4L2 MTIF3 PAM16 PCBD2 PCNT PRAP1 PRKAA2 SDCBP SH2D4A SMU1 SUV39H2 TEX11 TK1 TPM2 TRIM47 TXN TXN2 UBTD1 UQCC2 WASHC1 ZDHHC17 ZNF655	12 interacting genes: CD2BP2 CEBPA CERT1 H2BC21 LSM4 LSM8 MRFAP1 MSS51 RASSF10 TLX3 UBC YBX1
Entrez ID		93621	55234
HPRD ID		17589	11588
Ensembl ID		ENSG00000179010	ENSG00000122692
Uniprot IDs		B3KQA0 Q9Y605	A0MNN4 Q2TAY7
PDB IDs		Not available	5O9Z 6AHD 6Q8F 6Q8I 6Q8J 8H6K 8H6L 8QO9 8QZS
GO Terms Enriched among Interactors		SCAR Complex Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin-based Cell Projection Regulation Of Actin Nucleation Positive Regulation Of Actin Nucleation Regulation Of Cell Projection Assembly Regulation Of Lamellipodium Assembly Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Organelle Organization Regulation Of Lamellipodium Organization Regulation Of Organelle Organization Regulation Of Organelle Assembly Cytoskeleton Actin Filament Organization Neuron Migration Cell Projection Morphogenesis Centriole Filopodium Tip Signaling Adaptor Activity Autophagosome Lamellipodium	U4/U6 X U5 Tri-snRNP Complex Nucleoplasm Lsm2-8 Complex U6 SnRNP U6 SnRNA Binding RNA Splicing MRNA Processing Spliceosomal SnRNP Assembly RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding MRNA Metabolic Process Intermembrane Sphingolipid Transfer U2-type Precatalytic Spliceosome Response To Vitamin B2 C/EBP Complex Ceramide Transfer Activity CHOP-C/EBP Complex RNA Metabolic Process P-body RNA Processing Ribonucleoprotein Complex MiRNA Transport ER To Golgi Ceramide Transport