MAP1LC3B and ADNP

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		MAP1LC3B	ADNP
Gene Name		microtubule-associated protein 1 light chain 3 beta	activity-dependent neuroprotector homeobox
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Pre-autophagosomal Structure Autophagic Vacuole Membrane Intracellular Autophagic Vacuole Cytosol Microtubule Axoneme Endomembrane System Extrinsic Component Of Membrane Organelle Membrane Cytoplasmic Vesicle	Extracellular Space Nucleus
	Molecular Function	Protein Binding Microtubule Binding GABA Receptor Binding	DNA Binding Chromatin Binding Protein Binding Metal Ion Binding
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation Cellular Response To Nitrogen Starvation Nucleophagy Membrane Fusion	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Negative Regulation Of Neuron Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Major depressive disorder ( 22472876)
Protein-Protein Interactions		50 interactors: AAMP ADD1 ADNP ARFGAP1 ATG3 ATG4A ATG4B ATG7 BNIP3 BRD3 CASP8 CCSER2 CLTA DBI DBN1 DNMT3B EED EPS8 FAM134A FAM65A FUNDC1 FYCO1 GABARAPL2 GORASP2 KBTBD7 KLHL5 KXD1 LUC7L2 MKRN1 MRFAP1 MYBL2 NHP2L1 RAD1 RAP1GAP RPLP1 SAFB SHFM1 SMARCB1 SPAG9 SQSTM1 TAF7 TAX1BP1 TBC1D17 TBC1D25 TBC1D9 TBC1D9B THAP7 TMOD3 TNIP1 UPF2	3 interactors: CDC27 HIST3H3 MAP1LC3B
Entrez ID		81631	23394
HPRD ID		14358	09793
Ensembl ID		ENSG00000140941	ENSG00000101126
Uniprot IDs		H6UMI0 Q658J6 Q9GZQ8	Q9H2P0
PDB IDs		1V49 2LUE 2ZJD 3VTU 3VTV 3VTW
Enriched GO Terms of Interacting Partners?		Autophagy Mitochondrion Degradation Organelle Disassembly Nucleophagy Cellular Response To Nitrogen Starvation Macroautophagy Regulation Of Organelle Organization Cellular Response To Starvation Positive Regulation Of Metabolic Process Organelle Organization Positive Regulation Of Autophagy Response To Starvation Cellular Response To Nutrient Levels Autophagic Vacuole Assembly Cellular Response To Extracellular Stimulus Cellular Response To Stress Intracellular Transport Catabolic Process Mitochondrion Organization Regulation Of Cellular Component Organization C-terminal Protein Lipidation Protein Delipidation Membrane Organization Response To Stress Vacuole Organization Regulation Of Autophagy Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Complex Disassembly Establishment Of Localization In Cell Regulation Of Histone Modification Actin Filament Capping Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Hydrolase Activity Cellular Localization Negative Regulation Of Actin Filament Depolymerization Response To Nutrient Levels Cellular Component Assembly Protein Localization Regulation Of Ras Protein Signal Transduction Response To Extracellular Stimulus Response To Cobalt Ion Protein Targeting To Membrane Regulation Of Actin Filament Depolymerization Organelle Assembly Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Macroautophagy Negative Regulation Of Histone Acetylation	Metaphase/anaphase Transition Of Mitotic Cell Cycle Cellular Response To Nitrogen Starvation Organelle Organization Nucleophagy Protein K11-linked Ubiquitination Mitochondrion Degradation Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Organelle Disassembly Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Autophagic Vacuole Assembly Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Macroautophagy Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Proteasomal Protein Catabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Ligase Activity Telomere Maintenance Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Chromosome Organization Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Ubiquitination Vacuole Organization Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Membrane Fusion Catabolic Process Positive Regulation Of Protein Ubiquitination Cellular Response To Starvation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cellular Protein Catabolic Process Mitotic Cell Cycle Checkpoint Autophagy Protein Polyubiquitination
Tagcloud ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask	ac3 actually address anesthesia anesthetics aspirin biased brains counted dependently flexibility focusing infant injected ketamine nap napvsipq neurotoxicity nontoxic p6 p7 pbs pups rodent somatosensory stereological sterile trigger widespread
Tagcloud (Difference) ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask	ac3 actually address anesthesia anesthetics aspirin biased brains counted dependently flexibility focusing infant injected ketamine nap napvsipq neurotoxicity nontoxic p6 p7 pbs pups rodent somatosensory stereological sterile trigger widespread
Tagcloud (Intersection) ?