MRFAP1 and DNAJB5

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		MRFAP1	DNAJB5
Description		Morf4 family associated protein 1	DnaJ heat shock protein family (Hsp40) member B5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Perinuclear Region Of Cytoplasm	Nucleus Cytosol
	Molecular Function	Protein Binding	Protein Binding Unfolded Protein Binding Protein-folding Chaperone Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Protein Folding Response To Unfolded Protein
Pathways
Drugs
Diseases
GWAS			Response to quetiapine in schizophrenia ( 29503163)
Interacting Genes		40 interacting genes: ABI1 ABI2 ABI3 BRK1 C3orf62 C8orf33 CAVIN3 CCDC146 DCDC2 DNAJB5 DPY30 FCHSD2 GOLGA8F GOLGA8G HTT KIFC3 MAP1LC3B MORF4L1 MORF4L2 MTIF3 PAM16 PCBD2 PCNT PRAP1 PRKAA2 SDCBP SH2D4A SMU1 SUV39H2 TEX11 TK1 TPM2 TRIM47 TXN TXN2 UBTD1 UQCC2 WASHC1 ZDHHC17 ZNF655	11 interacting genes: ANK2 CACNA1A MRFAP1 MYBPC1 NOCT OBSCN SMAD2 SMAD3 TAF1 TBPL2 TTN
Entrez ID		93621	25822
HPRD ID		17589	07106
Ensembl ID		ENSG00000179010	ENSG00000137094
Uniprot IDs		B3KQA0 Q9Y605	A0A7I2RN43 O75953
PDB IDs
Enriched GO Terms of Interacting Partners?		SCAR Complex Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin-based Cell Projection Regulation Of Actin Nucleation Positive Regulation Of Actin Nucleation Regulation Of Cell Projection Assembly Regulation Of Lamellipodium Assembly Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Organelle Organization Regulation Of Lamellipodium Organization Regulation Of Organelle Organization Regulation Of Organelle Assembly Cytoskeleton Actin Filament Organization Neuron Migration Cell Projection Morphogenesis Centriole Filopodium Tip Signaling Adaptor Activity Autophagosome Lamellipodium	M Band Protein Localization To M-band Paraxial Mesoderm Morphogenesis Sarcomere Organization Structural Constituent Of Muscle Mesoderm Morphogenesis Pericardium Development SMAD Protein Complex Trophoblast Cell Migration Heteromeric SMAD Protein Complex Embryonic Foregut Morphogenesis Nodal Signaling Pathway Co-SMAD Binding Primary MiRNA Processing Titin Binding Transforming Growth Factor Beta Receptor Binding I-SMAD Binding Actomyosin Structure Organization Z Disc SMAD Protein Signal Transduction DNA-templated Transcription R-SMAD Binding Embryonic Cranial Skeleton Morphogenesis Activin Receptor Signaling Pathway Endoderm Development MiRNA Processing RNA Polymerase II-specific DNA-binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity Ureteric Bud Development Negative Regulation Of Ossification Protein Stabilization Transcription Regulator Complex Gastrulation Mesonephric Epithelium Development Mesonephric Tubule Development Mesoderm Formation Nuclear Receptor Binding Nuclear Inner Membrane Myofibril Phosphatase Binding Protein Localization To T-tubule Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Positive Regulation Of Androgen Receptor Signaling Pathway NADP Phosphatase Activity NADPH Phosphatase Activity Formation Of Primary Germ Layer Embryonic Pattern Specification Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Osteoblast Differentiation
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