MAP1LC3B and TMOD3

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		MAP1LC3B	TMOD3
Gene Name		microtubule-associated protein 1 light chain 3 beta	tropomodulin 3 (ubiquitous)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Pre-autophagosomal Structure Autophagic Vacuole Membrane Intracellular Autophagic Vacuole Cytosol Microtubule Axoneme Endomembrane System Extrinsic Component Of Membrane Organelle Membrane Cytoplasmic Vesicle	Striated Muscle Thin Filament
	Molecular Function	Protein Binding Microtubule Binding GABA Receptor Binding	Actin Binding Tropomyosin Binding
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation Cellular Response To Nitrogen Starvation Nucleophagy Membrane Fusion	Muscle Contraction Actin Filament Organization Myofibril Assembly Erythrocyte Development Pointed-end Actin Filament Capping Positive Regulation Of Mitotic Cell Cycle Phase Transition
Pathways
Drugs
Diseases
GWAS		Major depressive disorder ( 22472876)
Protein-Protein Interactions		50 interactors: AAMP ADD1 ADNP ARFGAP1 ATG3 ATG4A ATG4B ATG7 BNIP3 BRD3 CASP8 CCSER2 CLTA DBI DBN1 DNMT3B EED EPS8 FAM134A FAM65A FUNDC1 FYCO1 GABARAPL2 GORASP2 KBTBD7 KLHL5 KXD1 LUC7L2 MKRN1 MRFAP1 MYBL2 NHP2L1 RAD1 RAP1GAP RPLP1 SAFB SHFM1 SMARCB1 SPAG9 SQSTM1 TAF7 TAX1BP1 TBC1D17 TBC1D25 TBC1D9 TBC1D9B THAP7 TMOD3 TNIP1 UPF2	4 interactors: CSNK2A1 DUSP23 MAP1LC3B TNFSF11
Entrez ID		81631	29766
HPRD ID		14358	10389
Ensembl ID		ENSG00000140941	ENSG00000138594
Uniprot IDs		H6UMI0 Q658J6 Q9GZQ8	Q9NYL9
PDB IDs		1V49 2LUE 2ZJD 3VTU 3VTV 3VTW
Enriched GO Terms of Interacting Partners?		Autophagy Mitochondrion Degradation Organelle Disassembly Nucleophagy Cellular Response To Nitrogen Starvation Macroautophagy Regulation Of Organelle Organization Cellular Response To Starvation Positive Regulation Of Metabolic Process Organelle Organization Positive Regulation Of Autophagy Response To Starvation Cellular Response To Nutrient Levels Autophagic Vacuole Assembly Cellular Response To Extracellular Stimulus Cellular Response To Stress Intracellular Transport Catabolic Process Mitochondrion Organization Regulation Of Cellular Component Organization C-terminal Protein Lipidation Protein Delipidation Membrane Organization Response To Stress Vacuole Organization Regulation Of Autophagy Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Complex Disassembly Establishment Of Localization In Cell Regulation Of Histone Modification Actin Filament Capping Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Hydrolase Activity Cellular Localization Negative Regulation Of Actin Filament Depolymerization Response To Nutrient Levels Cellular Component Assembly Protein Localization Regulation Of Ras Protein Signal Transduction Response To Extracellular Stimulus Response To Cobalt Ion Protein Targeting To Membrane Regulation Of Actin Filament Depolymerization Organelle Assembly Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Macroautophagy Negative Regulation Of Histone Acetylation	Positive Regulation Of Corticotropin-releasing Hormone Secretion Regulation Of Corticotropin-releasing Hormone Secretion Positive Regulation Of ERK1 And ERK2 Cascade Via TNFSF11-mediated Signaling TNFSF11-mediated Signaling Pathway Positive Regulation Of Fever Generation By Positive Regulation Of Prostaglandin Secretion Positive Regulation Of Osteoclast Development Osteoclast Proliferation Regulation Of Osteoclast Development Positive Regulation Of Fever Generation Response To External Stimulus Regulation Of Fever Generation Positive Regulation Of Heat Generation Positive Regulation Of Prostaglandin Secretion Monocyte Chemotaxis Positive Regulation Of Bone Resorption Cellular Response To Nitrogen Starvation ERK1 And ERK2 Cascade Positive Regulation Of Icosanoid Secretion Nucleophagy Chemotaxis Mammary Gland Epithelial Cell Proliferation Positive Regulation Of Fatty Acid Transport Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Acute Inflammatory Response Mitochondrion Degradation Positive Regulation Of Tissue Remodeling Regulation Of Fatty Acid Transport Regulation Of Bone Resorption Bone Resorption Tumor Necrosis Factor-mediated Signaling Pathway Organelle Disassembly Phosphate-containing Compound Metabolic Process Mitotic Spindle Checkpoint Activation Of JUN Kinase Activity Negative Regulation Of Chromosome Segregation Autophagic Vacuole Assembly Mammary Gland Lobule Development Regulation Of Bone Remodeling Mammary Gland Alveolus Development Osteoclast Differentiation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division
Tagcloud ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask
Tagcloud (Difference) ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask
Tagcloud (Intersection) ?