MAP1LC3B and CLTA

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		MAP1LC3B	CLTA
Gene Name		microtubule-associated protein 1 light chain 3 beta	clathrin, light chain A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Pre-autophagosomal Structure Autophagic Vacuole Membrane Intracellular Autophagic Vacuole Cytosol Microtubule Axoneme Endomembrane System Extrinsic Component Of Membrane Organelle Membrane Cytoplasmic Vesicle	Cytosol Plasma Membrane Membrane Cytoplasmic Membrane-bounded Vesicle Clathrin Coat Clathrin Coat Of Trans-Golgi Network Vesicle Clathrin Coat Of Coated Pit Clathrin-coated Endocytic Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Clathrin Complex
	Molecular Function	Protein Binding Microtubule Binding GABA Receptor Binding	Molecular_function Structural Molecule Activity Protein Binding Clathrin Heavy Chain Binding Peptide Binding
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation Cellular Response To Nitrogen Starvation Nucleophagy Membrane Fusion	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Endocytosis Epidermal Growth Factor Receptor Signaling Pathway Axon Guidance Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Membrane Organization
Pathways			Retrograde neurotrophin signalling Axon guidance Gap junction degradation L1CAM interactions Signaling by Wnt Signaling by EGFRvIII in Cancer Recycling pathway of L1 EPH-ephrin mediated repulsion of cells Gap junction trafficking and regulation MHC class II antigen presentation EPH-Ephrin signaling EGFR downregulation Formation of annular gap junctions Signalling by NGF Gap junction trafficking Signaling by Ligand-Responsive EGFR Variants in Cancer NGF signalling via TRKA from the plasma membrane Signaling by Overexpressed Wild-Type EGFR in Cancer beta-catenin independent WNT signaling Signaling by EGFR WNT5A-dependent internalization of FZD4 Signaling by EGFR in Cancer PCP/CE pathway Adaptive Immune System
Drugs
Diseases
GWAS		Major depressive disorder ( 22472876)
Protein-Protein Interactions		50 interactors: AAMP ADD1 ADNP ARFGAP1 ATG3 ATG4A ATG4B ATG7 BNIP3 BRD3 CASP8 CCSER2 CLTA DBI DBN1 DNMT3B EED EPS8 FAM134A FAM65A FUNDC1 FYCO1 GABARAPL2 GORASP2 KBTBD7 KLHL5 KXD1 LUC7L2 MKRN1 MRFAP1 MYBL2 NHP2L1 RAD1 RAP1GAP RPLP1 SAFB SHFM1 SMARCB1 SPAG9 SQSTM1 TAF7 TAX1BP1 TBC1D17 TBC1D25 TBC1D9 TBC1D9B THAP7 TMOD3 TNIP1 UPF2	8 interactors: CLTC EGFR HIP1 HIP1R HSPA8 MAP1LC3B RGS2 SYNJ1
Entrez ID		81631	1211
HPRD ID		14358	00351
Ensembl ID		ENSG00000140941	ENSG00000122705
Uniprot IDs		H6UMI0 Q658J6 Q9GZQ8	C9J8P9 P09496
PDB IDs		1V49 2LUE 2ZJD 3VTU 3VTV 3VTW
Enriched GO Terms of Interacting Partners?		Autophagy Mitochondrion Degradation Organelle Disassembly Nucleophagy Cellular Response To Nitrogen Starvation Macroautophagy Regulation Of Organelle Organization Cellular Response To Starvation Positive Regulation Of Metabolic Process Organelle Organization Positive Regulation Of Autophagy Response To Starvation Cellular Response To Nutrient Levels Autophagic Vacuole Assembly Cellular Response To Extracellular Stimulus Cellular Response To Stress Intracellular Transport Catabolic Process Mitochondrion Organization Regulation Of Cellular Component Organization C-terminal Protein Lipidation Protein Delipidation Membrane Organization Response To Stress Vacuole Organization Regulation Of Autophagy Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Complex Disassembly Establishment Of Localization In Cell Regulation Of Histone Modification Actin Filament Capping Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Hydrolase Activity Cellular Localization Negative Regulation Of Actin Filament Depolymerization Response To Nutrient Levels Cellular Component Assembly Protein Localization Regulation Of Ras Protein Signal Transduction Response To Extracellular Stimulus Response To Cobalt Ion Protein Targeting To Membrane Regulation Of Actin Filament Depolymerization Organelle Assembly Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Macroautophagy Negative Regulation Of Histone Acetylation	Membrane Organization Endocytosis Vesicle-mediated Transport Regulation Of Cellular Component Organization Positive Regulation Of Synaptic Vesicle Uncoating Alkanesulfonate Metabolic Process Negative Regulation Of Fibril Organization Synaptic Vesicle Uncoating Regulation Of Synaptic Vesicle Membrane Organization Regulation Of Phospholipase Activity Post-Golgi Vesicle-mediated Transport Positive Regulation Of Endocytosis Neurotransmitter Secretion Positive Regulation Of Synaptic Transmission Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Regulation Of Neurotransmitter Levels Positive Regulation Of Synaptic Vesicle Endocytosis Negative Regulation Of Hyaluronan Biosynthetic Process Regulation Of Fibril Organization Activation Of Phospholipase A2 Activity Neurotransmitter Transport Positive Regulation Of Transport Cellular Protein Complex Disassembly Positive Regulation Of Phospholipase A2 Activity Clathrin Coat Disassembly Regulation Of Endocytosis Protein Complex Disassembly Regulation Of Synaptic Vesicle Endocytosis Response To Cobalamin Response To UV-A Regulation Of Adrenergic Receptor Signaling Pathway Response To Hydroxyisoflavone Positive Regulation Of Cardiac Muscle Contraction Cell Differentiation Negative Regulation Of CAMP-mediated Signaling Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Superoxide Anion Generation Negative Regulation Of Phospholipase Activity Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Synaptic Vesicle Priming Relaxation Of Vascular Smooth Muscle Learning Or Memory Golgi Vesicle Transport Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Catenin Import Into Nucleus Inositol Phosphate Dephosphorylation Relaxation Of Smooth Muscle Positive Regulation Of Striated Muscle Contraction Negative Regulation Of Muscle Hypertrophy
Tagcloud ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask	anaphase cdc20 cdh1 chromosomes clathrin cltc concentrated diffusely fzr1 g2 gst interactor kinetochore localize mad2b mad2l2 misaligned mitotic p11 prcc pull q21 rccs redistribution shuttle spindle tfe3 trimeric triskelion
Tagcloud (Difference) ?		akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask	anaphase cdc20 cdh1 chromosomes clathrin cltc concentrated diffusely fzr1 g2 gst interactor kinetochore localize mad2b mad2l2 misaligned mitotic p11 prcc pull q21 rccs redistribution shuttle spindle tfe3 trimeric triskelion
Tagcloud (Intersection) ?