PABPN1 and YWHAQ

Number of citations of the paper that reports this interaction (PMID 15161933)
63

Data Source:
BioGRID (pull down)

		PABPN1	YWHAQ
Gene Name		poly(A) binding protein, nuclear 1	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Ribonucleoprotein Complex	Cytoplasm Cytosol Focal Adhesion Membrane Cytoplasmic Vesicle Membrane Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding	Protein Binding Protein Domain Specific Binding Protein N-terminus Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription RNA Processing Muscle Contraction RNA Splicing Gene Expression Poly(A)+ MRNA Export From Nucleus Modulation By Virus Of Host Morphology Or Physiology Modulation By Virus Of Host Process Viral Life Cycle MRNA 3'-end Processing Modification By Virus Of Host MRNA Processing	Protein Targeting Apoptotic Process Small GTPase Mediated Signal Transduction Substantia Nigra Development Negative Regulation Of Transcription, DNA-templated Membrane Organization Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways		mRNA Splicing Inhibition of Host mRNA Processing and RNA Silencing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region Host Interactions with Influenza Factors mRNA 3'-end processing Processing of Intronless Pre-mRNAs Influenza Infection NS1 Mediated Effects on Host Pathways Processing of Capped Intronless Pre-mRNA RNA Polymerase II Transcription Termination	Activation of BAD and translocation to mitochondria Programmed Cell Death Translocation of GLUT4 to the plasma membrane Activation of BH3-only proteins Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS			Heart rate variability traits ( 22174390)
Protein-Protein Interactions		11 interactors: CARM1 DNAJB4 HNRNPA1 IL7R LATS1 PRMT3 SMARCA4 SNW1 STAU1 TNPO1 YWHAQ	231 interactors: AARS2 ABL1 ACSL4 AHCY AKT1S1 ANXA1 ANXA2 APC AR ARHGAP10 ARHGEF16 ATP5A1 BAD BAX BCAP31 BCR BRAF CABIN1 CAPN3 CBL CBLL1 CDC25A CDC25B CDC25C CDC5L CDK11B CDK14 CDK16 CDK17 CDK18 CDKN1A CDKN1B CEP170 CFL1 CHAF1A CKM CLTC COPS4 CSE1L CSNK1A1 CSNK2A1 CTPS1 DAB2IP DCPS DDX1 DDX3X DHX9 DISC1 DNMT1 DYNC1H1 E2F1 EFNB1 EIF4A3 ENO1 EPB41 EPB41L1 EPB41L3 ESR1 ESR2 EXO1 FASN FBLN1 FGR FSCN1 FSHR FXYD1 GAPDH GCN1L1 HADHA HAT1 HAX1 HDAC4 HDAC5 HDAC7 HIST1H2BG HIST2H4A HNRNPA1 HNRNPC HNRNPF HNRNPH1 HNRNPK HSPA1A HSPA8 HUS1 IARS2 ING1 IQGAP1 IRS2 ITGB4 KCNK15 KCNK3 KCNK9 KIAA1429 KIF1C KIF23 KIF5B KLC2 KLC3 KRT1 KRT9 LARP1 LARS2 LDHA LIMA1 LMNA LMNB1 LMO7 LYST MAGOH MAP3K3 MAP3K5 MARK2 MARK3 MCM3 MDM4 MED1 MEF2D MPL MPRIP MRPS27 MST1R MTNR1B MTOR MYCBP2 NADK NCL NCOA1 NCOA3 NDE1 NFATC1 NFATC2 NFATC4 NFKB1 NIF3L1 NME7 NOLC1 NUMA1 PABPC4 PABPN1 PAK4 PANK1 PCM1 PDCD6 PDE3A PDE3B PDK1 PDPK1 PDXK PFKFB2 PFKL PFN1 PGK1 PHLDB2 PI4KB PIK3C2B PIK3C3 PIK3CB PKM PPFIBP1 PRDX1 PRKCQ PRKCZ PRKD1 PRKDC PRMT5 PSME3 PTPN3 RAF1 RAI14 RCOR3 REM1 RFC1 RGS3 RGS7 RNASE2 RPL10A RPL15 RPL19 RPL7 RPLP0 RPLP2 RPS3 RUVBL2 SAMSN1 SH3BP2 SLC27A2 SLC8A1 SLC8A2 SLC8A3 SMAD9 SNRPE SPR SPTA1 SPTB SRSF3 SSBP1 SSFA2 SSX2IP TCP1 TERT THRA TLN1 TNF TNFAIP3 TP53BP2 TPI1 TPR TRIM28 TRIM42 TSC1 TSC2 TUBA1A TUBA3C TUBB UBQLN4 UCP2 UCP3 ULK4 USP8 VARS WDR61 WDR77 WEE1 WTAP WWC2 WWP1 YAP1 YWHAE YWHAG ZC3H13 ZHX2
Entrez ID		8106	10971
HPRD ID		03787	00886
Ensembl ID			ENSG00000134308
Uniprot IDs		Q86U42	B4DMT8 P27348
PDB IDs		3B4D 3B4M 3UCG	2BTP
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Viral Process Positive Regulation By Host Of Viral Transcription Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Peptidyl-arginine N-methylation Regulation Of Viral Process Histone Arginine Methylation Peptidyl-arginine Methylation Viral Process Interaction With Symbiont Positive Regulation Of Viral Transcription Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Viral Transcription Histone H3-R17 Methylation Histone Modification Methylation Keratinocyte Differentiation Chromosome Organization Positive Regulation Of Vitamin D Receptor Signaling Pathway Interleukin-7-mediated Signaling Pathway Histone H3-R2 Methylation Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Positive Regulation By Virus Of Viral Protein Levels In Host Cell Histone Methylation Nuclear Import Negative Regulation Of Cellular Metabolic Process Regulation Of Growth Plate Cartilage Chondrocyte Proliferation DNA Methylation On Cytosine Within A CG Sequence Epidermal Cell Differentiation RNA Localization Negative Regulation Of T Cell Mediated Cytotoxicity Chromatin Modification Regulation Of Nitrogen Compound Metabolic Process Regulation Of Vitamin D Receptor Signaling Pathway Definitive Erythrocyte Differentiation Aortic Smooth Muscle Cell Differentiation Protein Methylation Cellular Localization Intrinsic Apoptotic Signaling Pathway Glial Cell Fate Determination Methylation-dependent Chromatin Silencing Response To Organic Substance Chromatin Organization Intracellular Receptor Signaling Pathway Regulation Of Cell Differentiation Skin Development MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Intracellular MRNA Localization Regulation Of Signal Transduction Homeostasis Of Number Of Cells	Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Metabolic Process Organelle Organization Cellular Process Cellular Response To Organic Substance Regulation Of Cellular Component Organization Response To Organic Substance Response To Stimulus Positive Regulation Of Cellular Metabolic Process Developmental Process Positive Regulation Of Metabolic Process Regulation Of Cell Death Mitotic Cell Cycle Regulation Of Metabolic Process Response To Stress Cell Cycle Cellular Response To Stimulus Mitotic Cell Cycle Process Death Regulation Of Apoptotic Process Programmed Cell Death Regulation Of Protein Localization Intracellular Signal Transduction Apoptotic Process Cell Cycle Process Anatomical Structure Development Cell Death Regulation Of Cellular Localization System Development Multicellular Organismal Development Regulation Of Establishment Of Protein Localization Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Regulation Of Cell Cycle Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Abiotic Stimulus Positive Regulation Of Protein Metabolic Process Intracellular Transport Regulation Of Signaling Nucleobase-containing Compound Metabolic Process Cellular Response To Stress Regulation Of Phosphorylation Innate Immune Response MRNA Metabolic Process Cellular Localization Immune System Process Regulation Of Kinase Activity
Tagcloud ?		advances appreciated atypical avoid avoidance awareness biopsy cardinal chinese confusion decade dysphagia dystrophy earlier hoped investigations judicious last muscle muscular oculopharyngeal professionals proximal ptosis reserved rule underdiagnosed unnecessary weakness
Tagcloud (Difference) ?		advances appreciated atypical avoid avoidance awareness biopsy cardinal chinese confusion decade dysphagia dystrophy earlier hoped investigations judicious last muscle muscular oculopharyngeal professionals proximal ptosis reserved rule underdiagnosed unnecessary weakness
Tagcloud (Intersection) ?