PABPN1 and IL7R

Number of citations of the paper that reports this interaction (PMID 23151878)
3

Data Source:
BioGRID (unspecified method)

		PABPN1	IL7R
Gene Name		poly(A) binding protein, nuclear 1	interleukin 7 receptor
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Ribonucleoprotein Complex	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding	Antigen Binding Interleukin-7 Receptor Activity Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription RNA Processing Muscle Contraction RNA Splicing Gene Expression Poly(A)+ MRNA Export From Nucleus Modulation By Virus Of Host Morphology Or Physiology Modulation By Virus Of Host Process Viral Life Cycle MRNA 3'-end Processing Modification By Virus Of Host MRNA Processing	Regulation Of DNA Recombination Cell Morphogenesis Negative Regulation Of T Cell Mediated Cytotoxicity Immunoglobulin Production Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Regulation Of Cell Size Positive Regulation Of Gene Expression Cell Growth T Cell Differentiation Positive Regulation Of T Cell Differentiation In Thymus Interleukin-7-mediated Signaling Pathway B Cell Proliferation Lymph Node Development Homeostasis Of Number Of Cells
Pathways		mRNA Splicing Inhibition of Host mRNA Processing and RNA Silencing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region Host Interactions with Influenza Factors mRNA 3'-end processing Processing of Intronless Pre-mRNAs Influenza Infection NS1 Mediated Effects on Host Pathways Processing of Capped Intronless Pre-mRNA RNA Polymerase II Transcription Termination	Signaling by Interleukins Interleukin-7 signaling Cytokine Signaling in Immune system
Drugs
Diseases
GWAS			Multiple sclerosis ( 21244703 19525953 21833088) Primary biliary cirrhosis ( 23000144 21399635) Type 1 diabetes ( 17554260) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		11 interactors: CARM1 DNAJB4 HNRNPA1 IL7R LATS1 PRMT3 SMARCA4 SNW1 STAU1 TNPO1 YWHAQ	104 interactors: ALYREF CIRBP CPSF1 CRLF2 DDX21 DDX39B DDX3X DDX5 DHX36 DHX9 EIF2AK2 ELAVL1 EMG1 FAU FUS FYN G3BP1 GNB2L1 H1FX HIST1H1C HIST1H1E HIST2H2BE HNRNPA0 HNRNPA3 HNRNPAB HNRNPC HNRNPD HNRNPDL HNRNPH3 HNRNPL HNRNPR HNRNPU HNRNPUL1 HNRNPUL2 IL2RG IL7 ILF2 ILF3 JAK1 JAK3 KIT LYN MAP4 NCL NONO PABPC1 PABPC4 PABPN1 PIK3R1 PTBP1 PTK2B PTMA PURA PURB QKI RAD21 RBM3 RBMX RPL15 RPL18 RPL22 RPL29 RPL30 RPL31 RPL6 RPL7 RPL8 RPS20 RPS3 RPSA RRAGA RSL1D1 SAFB SF1 SF3A1 SF3B1 SNRNP70 SNRPA SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SRP14 SRP9 SRSF3 SRSF9 SSB STAT3 STAT5A STAT5B SYNCRIP TOE1 TOP1 TSLP U2AF1 U2AF2 YBX1 YBX3 YWHAE YWHAG ZNF787
Entrez ID		8106	3575
HPRD ID		03787	00893
Ensembl ID			ENSG00000168685
Uniprot IDs		Q86U42	D6RGV2 D9N160 P16871
PDB IDs		3B4D 3B4M 3UCG	3DI2 3DI3 3UP1
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Viral Process Positive Regulation By Host Of Viral Transcription Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Peptidyl-arginine N-methylation Regulation Of Viral Process Histone Arginine Methylation Peptidyl-arginine Methylation Viral Process Interaction With Symbiont Positive Regulation Of Viral Transcription Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Viral Transcription Histone H3-R17 Methylation Histone Modification Methylation Keratinocyte Differentiation Chromosome Organization Positive Regulation Of Vitamin D Receptor Signaling Pathway Interleukin-7-mediated Signaling Pathway Histone H3-R2 Methylation Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Positive Regulation By Virus Of Viral Protein Levels In Host Cell Histone Methylation Nuclear Import Negative Regulation Of Cellular Metabolic Process Regulation Of Growth Plate Cartilage Chondrocyte Proliferation DNA Methylation On Cytosine Within A CG Sequence Epidermal Cell Differentiation RNA Localization Negative Regulation Of T Cell Mediated Cytotoxicity Chromatin Modification Regulation Of Nitrogen Compound Metabolic Process Regulation Of Vitamin D Receptor Signaling Pathway Definitive Erythrocyte Differentiation Aortic Smooth Muscle Cell Differentiation Protein Methylation Cellular Localization Intrinsic Apoptotic Signaling Pathway Glial Cell Fate Determination Methylation-dependent Chromatin Silencing Response To Organic Substance Chromatin Organization Intracellular Receptor Signaling Pathway Regulation Of Cell Differentiation Skin Development MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Intracellular MRNA Localization Regulation Of Signal Transduction Homeostasis Of Number Of Cells	MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing RNA Splicing MRNA Processing RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Viral Process RNA Biosynthetic Process SRP-dependent Cotranslational Protein Targeting To Membrane Termination Of RNA Polymerase II Transcription Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Cellular Macromolecule Biosynthetic Process Regulation Of MRNA Stability Regulation Of RNA Stability Macromolecule Biosynthetic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Protein Localization To Endoplasmic Reticulum Viral Life Cycle Cytoplasmic Transport Posttranscriptional Regulation Of Gene Expression MRNA Stabilization RNA 3'-end Processing MRNA 3'-end Processing RNA Catabolic Process Viral Transcription Cellular Metabolic Process Protein Targeting To Membrane DNA-templated Transcription, Termination Protein Targeting Nuclear-transcribed MRNA Catabolic Process Establishment Of Protein Localization To Organelle MRNA Catabolic Process Ribonucleoprotein Complex Assembly Regulation Of Translation Ribonucleoprotein Complex Biogenesis Biosynthetic Process Protein Localization To Organelle Translational Termination Establishment Of Protein Localization To Membrane Intracellular Transport Translational Elongation
Tagcloud ?		advances appreciated atypical avoid avoidance awareness biopsy cardinal chinese confusion decade dysphagia dystrophy earlier hoped investigations judicious last muscle muscular oculopharyngeal professionals proximal ptosis reserved rule underdiagnosed unnecessary weakness	aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Difference) ?		advances appreciated atypical avoid avoidance awareness biopsy cardinal chinese confusion decade dysphagia dystrophy earlier hoped investigations judicious last muscle muscular oculopharyngeal professionals proximal ptosis reserved rule underdiagnosed unnecessary weakness	aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Intersection) ?