PABPN1 and TNPO1

Number of citations of the paper that reports this interaction (PMID 10688363)
24

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		PABPN1	TNPO1
Gene Name		poly(A) binding protein, nuclear 1	transportin 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Ribonucleoprotein Complex	Nucleus Cytoplasm Cytosol Extracellular Vesicular Exosome Primary Cilium
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding	Protein Binding Nuclear Localization Sequence Binding Ran GTPase Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription RNA Processing Muscle Contraction RNA Splicing Gene Expression Poly(A)+ MRNA Export From Nucleus Modulation By Virus Of Host Morphology Or Physiology Modulation By Virus Of Host Process Viral Life Cycle MRNA 3'-end Processing Modification By Virus Of Host MRNA Processing	Protein Import Into Nucleus, Translocation Organelle Organization Gene Expression Viral Process
Pathways		mRNA Splicing Inhibition of Host mRNA Processing and RNA Silencing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region Host Interactions with Influenza Factors mRNA 3'-end processing Processing of Intronless Pre-mRNAs Influenza Infection NS1 Mediated Effects on Host Pathways Processing of Capped Intronless Pre-mRNA RNA Polymerase II Transcription Termination	Regulation of mRNA stability by proteins that bind AU-rich elements Organelle biogenesis and maintenance Assembly of the primary cilium Tristetraprolin (TTP) destabilizes mRNA Intraflagellar transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: CARM1 DNAJB4 HNRNPA1 IL7R LATS1 PRMT3 SMARCA4 SNW1 STAU1 TNPO1 YWHAQ	17 interactors: ELAVL1 HIST2H2BE HIST3H3 HNRNPA1 HNRNPD NUP153 NUP214 NUP98 NXF1 PABPN1 RAN RANBP2 RGPD5 RPL23A RPL5 RPS7 SRP19
Entrez ID		8106	3842
HPRD ID		03787	04210
Ensembl ID			ENSG00000083312
Uniprot IDs		Q86U42	Q92973
PDB IDs		3B4D 3B4M 3UCG	1QBK 2H4M 2OT8 2QMR 2Z5J 2Z5K 2Z5M 2Z5N 2Z5O 4FDD 4FQ3 4JLQ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Viral Process Positive Regulation By Host Of Viral Transcription Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Peptidyl-arginine N-methylation Regulation Of Viral Process Histone Arginine Methylation Peptidyl-arginine Methylation Viral Process Interaction With Symbiont Positive Regulation Of Viral Transcription Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Viral Transcription Histone H3-R17 Methylation Histone Modification Methylation Keratinocyte Differentiation Chromosome Organization Positive Regulation Of Vitamin D Receptor Signaling Pathway Interleukin-7-mediated Signaling Pathway Histone H3-R2 Methylation Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Positive Regulation By Virus Of Viral Protein Levels In Host Cell Histone Methylation Nuclear Import Negative Regulation Of Cellular Metabolic Process Regulation Of Growth Plate Cartilage Chondrocyte Proliferation DNA Methylation On Cytosine Within A CG Sequence Epidermal Cell Differentiation RNA Localization Negative Regulation Of T Cell Mediated Cytotoxicity Chromatin Modification Regulation Of Nitrogen Compound Metabolic Process Regulation Of Vitamin D Receptor Signaling Pathway Definitive Erythrocyte Differentiation Aortic Smooth Muscle Cell Differentiation Protein Methylation Cellular Localization Intrinsic Apoptotic Signaling Pathway Glial Cell Fate Determination Methylation-dependent Chromatin Silencing Response To Organic Substance Chromatin Organization Intracellular Receptor Signaling Pathway Regulation Of Cell Differentiation Skin Development MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Intracellular MRNA Localization Regulation Of Signal Transduction Homeostasis Of Number Of Cells	Cytoplasmic Transport Viral Life Cycle Viral Process Viral Transcription Intracellular Transport Establishment Of Protein Localization To Organelle MRNA Transport RNA Transport Protein Targeting Nucleocytoplasmic Transport Nuclear Transport RNA Localization Protein Localization To Organelle Establishment Of Localization In Cell Nuclear Import Cellular Localization Gene Expression Intracellular Protein Transport Protein Transport Mitotic Nuclear Envelope Disassembly Establishment Of Protein Localization Nuclear Export Nuclear Envelope Disassembly Membrane Organization Cellular Protein Localization Protein Localization Nuclear Envelope Organization RNA Export From Nucleus Glucose Transport Hexose Transport SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Regulation Of Glucose Transport Establishment Of Protein Localization To Endoplasmic Reticulum MRNA Metabolic Process Protein Import Into Nucleus Transport Nucleus Organization Protein Localization To Endoplasmic Reticulum Carbohydrate Transport Protein Import Protein Targeting To Membrane Protein Localization To Nucleus Nucleobase-containing Compound Metabolic Process RNA Catabolic Process Nuclear Pore Complex Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process
Tagcloud ?		advances appreciated atypical avoid avoidance awareness biopsy cardinal chinese confusion decade dysphagia dystrophy earlier hoped investigations judicious last muscle muscular oculopharyngeal professionals proximal ptosis reserved rule underdiagnosed unnecessary weakness	box creb cysteine damaging detail disulfides examples forkhead foxo4 give h2o2 instance intermolecular merely mini nadph o4 oxidase oxidation peroxide perturbs phenomenon redox respiration reversible signalling translating transportin ultimately
Tagcloud (Difference) ?		advances appreciated atypical avoid avoidance awareness biopsy cardinal chinese confusion decade dysphagia dystrophy earlier hoped investigations judicious last muscle muscular oculopharyngeal professionals proximal ptosis reserved rule underdiagnosed unnecessary weakness	box creb cysteine damaging detail disulfides examples forkhead foxo4 give h2o2 instance intermolecular merely mini nadph o4 oxidase oxidation peroxide perturbs phenomenon redox respiration reversible signalling translating transportin ultimately
Tagcloud (Intersection) ?