ACTA1 and CYTH1

Number of citations of the paper that reports this interaction (PMID 11438522)
7

Data Source:
HPRD (in vitro)

		ACTA1	CYTH1
Gene Name		actin, alpha 1, skeletal muscle	cytohesin 1
Image
Gene Ontology Annotations	Cellular Component	Stress Fiber Extracellular Space Cytosol Striated Muscle Thin Filament Actin Filament Actin Cytoskeleton Sarcomere Extracellular Vesicular Exosome Blood Microparticle	Cytoplasm Trans-Golgi Network Cytosol Plasma Membrane Tight Junction Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Myosin Binding ADP Binding	ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding
	Biological Process	Muscle Contraction Response To Mechanical Stimulus Response To Extracellular Stimulus Response To Lithium Ion Cell Growth Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Skeletal Muscle Fiber Adaptation Response To Steroid Hormone Skeletal Muscle Fiber Development	Vesicle-mediated Transport Regulation Of Cell Adhesion Regulation Of ARF Protein Signal Transduction Positive Regulation Of GTPase Activity Establishment Of Epithelial Cell Polarity
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS
Protein-Protein Interactions		107 interactors: ABL1 ABRA ACTR10 ACTR1B ADSS AFAP1 AIF1 AJUBA AMOT CCIN CCT2 CCT4 CCT5 CFL1 CLIC5 CNN1 CORO2B COTL1 CTNND1 CTTN CYFIP1 CYTH1 DHX9 DLG1 DMD DNASE1 DNMBP DTNA EGFR EPB41 EPB41L2 EPS8 FGD4 FHOD1 FSCN1 GAS2 GAS7 GC GSN HCLS1 HDAC4 HIP1R HTRA2 IQGAP1 ITGA2 ITPKA KIF23 KLHL20 LASP1 MACF1 MAP1A MIB2 MINPP1 MYL1 MYLK MYO10 MYO6 MYO7A MYO9B NEXN NR3C2 NRAP PAK1 PARVA PCYT1B PFDN1 PFN1 PHACTR1 PLD1 PPP1R9B PRKCA PRKCD PRKCE RAC1 RPS6KB1 S100A1 S100A4 SCIN SMTN SNCA SORBS1 SPRR1A SPTA1 SPTAN1 SPTBN2 TAGLN TJP1 TLN1 TMSB4X TMSB4Y TNNI1 TNNI3 TNNI3K TP53 TPM2 TPM3 TRIM55 TRIM63 TTN USP25 USP6NL UTRN VASP VAV1 VCL VIL1 XIRP1	12 interactors: ACTA1 ARF1 ARF6 ARFRP1 ARR3 CYTIP GNAQ IPCEF1 ITGB2 ITSN1 PRKCD TRIM23
Entrez ID		58	9267
HPRD ID		00030	01630
Ensembl ID		ENSG00000143632	ENSG00000108669
Uniprot IDs		P68133 Q5T8M7	Q15438
PDB IDs		1T44	1BC9 4A4P
Enriched GO Terms of Interacting Partners?		Actin Filament-based Process Actin Cytoskeleton Organization Cytoskeleton Organization Actin Filament Organization Regulation Of Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Movement Of Cell Or Subcellular Component Regulation Of Actin Filament-based Process Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Cellular Component Organization Regulation Of Actin Filament Polymerization Regulation Of Organelle Organization Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Actin Filament-based Movement Muscle Contraction Muscle System Process Cell Projection Organization Organelle Organization Negative Regulation Of Protein Polymerization Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Cytoskeleton Organization Cellular Component Assembly Developmental Process Anatomical Structure Morphogenesis Anatomical Structure Development Negative Regulation Of Protein Complex Assembly System Development Actin-mediated Cell Contraction Response To Wounding Locomotion Cell Development Response To External Stimulus Cell Differentiation Wound Healing Multicellular Organismal Development Cell Morphogenesis Negative Regulation Of Cytoskeleton Organization Positive Regulation Of Cellular Component Biogenesis Tissue Development Cell Projection Morphogenesis Chemotaxis Positive Regulation Of Organelle Organization Cell Part Morphogenesis Neuron Development Actin Polymerization Or Depolymerization Blood Coagulation Hemostasis Cell Junction Assembly	Small GTPase Mediated Signal Transduction Vesicle-mediated Transport Response To Stimulus Cellular Response To Stimulus Signal Transduction Intracellular Signal Transduction Signaling Regulation Of Filopodium Assembly Regulation Of Phosphorylation Cell Communication Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Positive Regulation Of Phospholipase Activity Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Phospholipase Activity Post-Golgi Vesicle-mediated Transport Positive Regulation Of Lipase Activity Regulation Of Actin Filament-based Process Protein Stabilization Positive Regulation Of Phospholipid Catabolic Process Skeletal Muscle Fiber Adaptation Apoptotic Process Blood Coagulation Hemostasis Programmed Cell Death Lymphocyte Proliferation Cell Death Mononuclear Cell Proliferation Death Regulation Of Protein Phosphorylation Interleukin-10 Production Regulation Of Cell Projection Assembly Leukocyte Proliferation Regulation Of Cytoskeleton Organization Negative Regulation Of Filopodium Assembly Regulation Of Protein Stability Interleukin-12 Production Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Body Fluid Levels Positive Regulation Of Ceramide Biosynthetic Process Wound Healing Skeletal Muscle Thin Filament Assembly Regulation Of Actin Filament Polymerization Embryonic Morphogenesis Endocytosis
Tagcloud ?		annotation assembled biomedical contigs cox1 discover eef1a1 eef1g ends est ests expand gluconeogenesis libraries livestock loin normalized ontology pfam pig pituitary porcine singletons sla slc25a6 susflecks tags transducin wd40
Tagcloud (Difference) ?		annotation assembled biomedical contigs cox1 discover eef1a1 eef1g ends est ests expand gluconeogenesis libraries livestock loin normalized ontology pfam pig pituitary porcine singletons sla slc25a6 susflecks tags transducin wd40
Tagcloud (Intersection) ?