ACTA1 and TMSB4Y

Number of citations of the paper that reports this interaction (PMID 8416954)
23

Data Source:
BioGRID (pull down)

		ACTA1	TMSB4Y
Gene Name		actin, alpha 1, skeletal muscle	thymosin beta 4, Y-linked
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Extracellular Space Cytosol Striated Muscle Thin Filament Actin Filament Actin Cytoskeleton Sarcomere Extracellular Vesicular Exosome Blood Microparticle	Cytoplasm Cytoskeleton
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Myosin Binding ADP Binding	Actin Monomer Binding
	Biological Process	Muscle Contraction Response To Mechanical Stimulus Response To Extracellular Stimulus Response To Lithium Ion Cell Growth Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Skeletal Muscle Fiber Adaptation Response To Steroid Hormone Skeletal Muscle Fiber Development	Actin Filament Organization Regulation Of Actin Polymerization Or Depolymerization Sequestering Of Actin Monomers
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS
Protein-Protein Interactions		107 interactors: ABL1 ABRA ACTR10 ACTR1B ADSS AFAP1 AIF1 AJUBA AMOT CCIN CCT2 CCT4 CCT5 CFL1 CLIC5 CNN1 CORO2B COTL1 CTNND1 CTTN CYFIP1 CYTH1 DHX9 DLG1 DMD DNASE1 DNMBP DTNA EGFR EPB41 EPB41L2 EPS8 FGD4 FHOD1 FSCN1 GAS2 GAS7 GC GSN HCLS1 HDAC4 HIP1R HTRA2 IQGAP1 ITGA2 ITPKA KIF23 KLHL20 LASP1 MACF1 MAP1A MIB2 MINPP1 MYL1 MYLK MYO10 MYO6 MYO7A MYO9B NEXN NR3C2 NRAP PAK1 PARVA PCYT1B PFDN1 PFN1 PHACTR1 PLD1 PPP1R9B PRKCA PRKCD PRKCE RAC1 RPS6KB1 S100A1 S100A4 SCIN SMTN SNCA SORBS1 SPRR1A SPTA1 SPTAN1 SPTBN2 TAGLN TJP1 TLN1 TMSB4X TMSB4Y TNNI1 TNNI3 TNNI3K TP53 TPM2 TPM3 TRIM55 TRIM63 TTN USP25 USP6NL UTRN VASP VAV1 VCL VIL1 XIRP1	6 interactors: ACTA1 ACTG1 EWSR1 POT1 TERF1 TERF2IP
Entrez ID		58	9087
HPRD ID		00030	02458
Ensembl ID		ENSG00000143632	ENSG00000154620
Uniprot IDs		P68133 Q5T8M7	O14604
PDB IDs		1T44
Enriched GO Terms of Interacting Partners?		Actin Filament-based Process Actin Cytoskeleton Organization Cytoskeleton Organization Actin Filament Organization Regulation Of Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Movement Of Cell Or Subcellular Component Regulation Of Actin Filament-based Process Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Cellular Component Organization Regulation Of Actin Filament Polymerization Regulation Of Organelle Organization Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Actin Filament-based Movement Muscle Contraction Muscle System Process Cell Projection Organization Organelle Organization Negative Regulation Of Protein Polymerization Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Cytoskeleton Organization Cellular Component Assembly Developmental Process Anatomical Structure Morphogenesis Anatomical Structure Development Negative Regulation Of Protein Complex Assembly System Development Actin-mediated Cell Contraction Response To Wounding Locomotion Cell Development Response To External Stimulus Cell Differentiation Wound Healing Multicellular Organismal Development Cell Morphogenesis Negative Regulation Of Cytoskeleton Organization Positive Regulation Of Cellular Component Biogenesis Tissue Development Cell Projection Morphogenesis Chemotaxis Positive Regulation Of Organelle Organization Cell Part Morphogenesis Neuron Development Actin Polymerization Or Depolymerization Blood Coagulation Hemostasis Cell Junction Assembly	Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance RNA-dependent DNA Replication Telomere Maintenance Via Telomere Lengthening Telomere Maintenance Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Negative Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomerase Activity Regulation Of Chromosome Organization Negative Regulation Of DNA Biosynthetic Process DNA Replication Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Homeostatic Process Myofibril Assembly Organelle Organization Positive Regulation Of DNA Strand Elongation Negative Regulation Of DNA Recombination At Telomere Actomyosin Structure Organization Regulation Of DNA Replication Skeletal Muscle Fiber Adaptation Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Cellular Component Assembly Striated Muscle Cell Development Telomeric Loop Formation Age-dependent Telomere Shortening Telomere Formation Via Telomerase Muscle Cell Development Telomere Maintenance Via Telomere Shortening Regulation Of Organelle Organization Protection From Non-homologous End Joining At Telomere Striated Muscle Cell Differentiation Chromosome Organization Protein Localization To Chromosome, Telomeric Region Positive Regulation Of Helicase Activity DNA Metabolic Process Skeletal Muscle Thin Filament Assembly Positive Regulation Of Telomerase Activity Telomere Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Skeletal Myofibril Assembly Replicative Cell Aging Skeletal Muscle Adaptation Negative Regulation Of Transferase Activity Regulation Of Nuclear Cell Cycle DNA Replication
Tagcloud ?		annotation assembled biomedical contigs cox1 discover eef1a1 eef1g ends est ests expand gluconeogenesis libraries livestock loin normalized ontology pfam pig pituitary porcine singletons sla slc25a6 susflecks tags transducin wd40
Tagcloud (Difference) ?		annotation assembled biomedical contigs cox1 discover eef1a1 eef1g ends est ests expand gluconeogenesis libraries livestock loin normalized ontology pfam pig pituitary porcine singletons sla slc25a6 susflecks tags transducin wd40
Tagcloud (Intersection) ?