CYTH1 and SNAPC5

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		CYTH1	SNAPC5
Description		cytohesin 1	small nuclear RNA activating complex polypeptide 5
Image
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Cytoplasmic Side Of Plasma Membrane Membrane Anchoring Junction	Nucleus Nucleoplasm Nucleolus Nuclear Body
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding	RNA Polymerase III General Transcription Initiation Factor Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity
	Biological Process	Vesicle-mediated Transport Regulation Of Cell Adhesion Regulation Of ARF Protein Signal Transduction Establishment Of Epithelial Cell Polarity	Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase III Promoter SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III
Pathways		Intra-Golgi traffic	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Anxiety and major depressive disorder ( 24047446) Atrial fibrillation ( 30061737) HDL cholesterol levels ( 32203549) Pulse pressure ( 27841878 30578418) Red cell distribution width ( 32888494) Systolic blood pressure ( 27841878)
Interacting Genes		13 interacting genes: ACTA1 ARF1 ARF6 ARFRP1 CYTIP FOSL2 GNAQ ITGB2 ITSN1 PCNT PRKCD SNAPC5 TRIM23	43 interacting genes: AMOT ARHGEF38 BATF BFSP2 BLOC1S1 BRCC3 CBY2 CCDC196 CDCA8 CREB5 CREBBP CYTH1 CYTH4 DDIT3 EMILIN1 FAM9C GALR1 GORAB GRIPAP1 HMG20B ITGB3BP JUN LMO2 MBD3L1 MCRS1 MYF5 NDEL1 NMI NOL4 NUDT10 NUP62 POLR2J RNF4 S100Z SNAPC1 SNAPC4 STMN4 TRAPPC2 TRAPPC2B TXLNB ZNF177 ZNF559-ZNF177 ZNRD2
Entrez ID		9267	10302
HPRD ID		01630	16183
Ensembl ID		ENSG00000108669	ENSG00000174446
Uniprot IDs		B7Z9W0 K7ENQ8 Q15438	O75971
PDB IDs		1BC9 4A4P	7ZWC 7ZWD 7ZX7 7ZX8 7ZXE
Enriched GO Terms of Interacting Partners?		GTPase Activity GTP Binding Endomembrane System Nucleotide Binding Vesicle-mediated Transport Positive Regulation Of Establishment Of Protein Localization Regulation Of Superoxide Anion Generation Positive Regulation Of Superoxide Anion Generation Regulation Of Superoxide Metabolic Process Sarcomere Cellular Localization Protein Transport Intracellular Protein Transport Regulation Of Transport Membrane Invagination Mitotic Cleavage Furrow Ingression Regulation Of Vesicle-mediated Transport Presynaptic Endocytosis Regulation Of Establishment Of Protein Localization Positive Regulation Of Transport Regulation Of Cellular Localization Regulation Of Filopodium Assembly Synaptic Vesicle Endocytosis Regulation Of Dendritic Spine Development Erythrocyte Apoptotic Process Positive Regulation Of Protein Transport Fat Cell Apoptotic Process B Cell Proliferation Regulation Of Platelet Activation Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Glucosylceramide Catabolic Process Endosomal Transport Regulation Of Actin Filament Organization Intracellular Protein Localization Intracellular Transport GDP Binding Enzyme Activator Activity Regulation Of Biological Quality Cleavage Furrow Ingression Regulation Of Endocytosis Positive Regulation Of Secretion By Cell Protein Localization To Membrane G Protein Activity Lung Connective Tissue Development Alveolar Secondary Septum Development Regulation Of Body Fluid Levels Integrin AlphaM-beta2 Complex Integrin AlphaX-beta2 Complex Positive Regulation Of Reactive Oxygen Species Metabolic Process Integrin AlphaL-beta2 Complex	SnRNA-activating Protein Complex Peptidyl-lysine Acetylation Protein Binding Integrated Stress Response Signaling RNA Polymerase II Transcription Regulator Complex CAMP Response Element Binding TRAPPII Protein Complex TRAPPIII Protein Complex SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III RNA Polymerase III General Transcription Initiation Factor Activity Positive Regulation Of Mitotic Cytokinesis Centrosome Separation Mitotic Centrosome Separation SnRNA Transcription Regulation Of Mitotic Cytokinesis
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