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ACTA1 and CLIC5
Number of citations of the paper that reports this interaction (PubMedID
10793131
)
42
Data Source:
HPRD
(in vitro)
ACTA1
CLIC5
Description
actin alpha 1, skeletal muscle
chloride intracellular channel 5
Image
GO Annotations
Cellular Component
Stress Fiber
Extracellular Space
Cytoplasm
Cytosol
Cytoskeleton
Striated Muscle Thin Filament
Actin Filament
Actin Cytoskeleton
Sarcomere
Lamellipodium
Filopodium
Cell Body
Extracellular Exosome
Blood Microparticle
Cytoplasm
Mitochondrion
Golgi Apparatus
Centrosome
Cytoskeleton
Plasma Membrane
Cell Cortex
Actin Cytoskeleton
Membrane
Apical Plasma Membrane
Stereocilium
Monoatomic Ion Channel Complex
Chloride Channel Complex
Cell Projection
Extracellular Exosome
Molecular Function
Nucleotide Binding
Structural Constituent Of Cytoskeleton
Protein Binding
ATP Binding
Hydrolase Activity
Myosin Binding
ADP Binding
Chloride Channel Activity
Protein Binding
Oxidoreductase Activity
Biological Process
Muscle Contraction
Positive Regulation Of Gene Expression
Skeletal Muscle Thin Filament Assembly
Skeletal Muscle Fiber Development
Mesenchyme Migration
Monoatomic Ion Transport
Chloride Transport
Female Pregnancy
Visual Perception
Sensory Perception Of Sound
Monoatomic Ion Transmembrane Transport
Chloride Transmembrane Transport
Pathways
Striated Muscle Contraction
Regulation of CDH1 Function
Formation of the dystrophin-glycoprotein complex (DGC)
Formation of the dystrophin-glycoprotein complex (DGC)
Sensory processing of sound by inner hair cells of the cochlea
Sensory processing of sound by outer hair cells of the cochlea
Drugs
Latrunculin A
Sucrose
Ulapualide A
Kabiramide C
Jaspisamide A
Tmr
1-Methylhistidine
Phosphoaminophosphonic Acid-Adenylate Ester
Aplyronine A
Reidispongiolide A
Reidispongiolide C
Sphinxolide B
Latrunculin B
Diseases
Cap myopathy
Congenital fiber type disproportion (CFTD)
Nemaline myopathy
GWAS
Blond vs. brown/black hair color (
30531825
)
Blood protein levels (
30072576
)
Cerebrospinal AB1-42 levels in normal cognition (
29274321
)
Coronary artery disease in type 1 diabetes (
32077919
)
Gout (normal type) (
32238385
)
Heel bone mineral density (
30598549
)
Intraocular pressure (
29785010
)
Itch intensity from mosquito bite (
28199695
)
LDL cholesterol levels in HIV infection (
33109212
)
Mosquito bite size (
28199695
)
Periodontal microbiota (
22699663
)
Interacting Genes
115 interacting genes:
ABL1
ABRA
ACTR10
ACTR1B
ADSS2
AFAP1
AIF1
AJUBA
AMOT
ANXA2
BIN1
CCIN
CCT2
CCT4
CCT5
CFL1
CLIC5
CNN1
CORO2B
COTL1
CTNND1
CTTN
CYFIP1
CYTH1
DHX9
DLG1
DMD
DNASE1
DNMBP
DTNA
DUX4L9
EGFR
EPB41
EPB41L2
EPS8
FGD4
FHOD1
FSCN1
GAS2
GAS7
GC
GSN
HCLS1
HDAC4
HIP1R
HSPB2
HTRA2
IQGAP1
ITGA2
ITPKA
KIF23
KLHL20
LASP1
LINC00624
MACF1
MAP1A
MAPT
MIB2
MINPP1
MYL1
MYLK
MYO10
MYO6
MYO7A
MYO9B
NEXN
NR3C2
NRAP
PAK1
PARVA
PCYT1B
PFDN1
PFN1
PHACTR1
PLD1
PPP1R9B
PRKCA
PRKCD
PRKCE
RAC1
RNF167
RPS6KB1
S100A1
S100A4
SCIN
SMTN
SNCA
SORBS1
SPRR1A
SPTA1
SPTAN1
SPTBN2
TAGLN
TJP1
TLN1
TMSB4X
TMSB4Y
TNNI1
TNNI3
TNNI3K
TP53
TPM2
TPM3
TRIM55
TRIM63
TTN
UBC
USP25
USP6NL
UTRN
VASP
VAV1
VCL
VIL1
XIRP1
8 interacting genes:
ACTA1
ACTN1
EZR
GSN
IQGAP1
LAMTOR5
SRPK1
TPRN
Entrez ID
58
53405
HPRD ID
00030
06292
Ensembl ID
ENSG00000143632
ENSG00000112782
Uniprot IDs
P68133
A0A2R8YGW2
Q49AE1
Q53G01
Q9NZA1
PDB IDs
7RNS
7RNU
7RNV
9DUU
9DUV
6Y2H
8Q4I
8Q4J
Enriched GO Terms of Interacting Partners
?
Actin Binding
Actin Filament Binding
Cytoskeleton
Actin Cytoskeleton
Actin Filament-based Process
Cytoplasm
Actin Filament Organization
Regulation Of Supramolecular Fiber Organization
Regulation Of Actin Filament Organization
Actin Cytoskeleton Organization
Supramolecular Fiber Organization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Cytoskeleton Organization
Regulation Of Actin Filament Polymerization
Regulation Of Actin Filament Length
Regulation Of Cytoskeleton Organization
Regulation Of Actin Filament-based Process
Cytosol
Regulation Of Cellular Component Size
Regulation Of Protein-containing Complex Assembly
Cell Cortex
Cytoskeleton Organization
Regulation Of Organelle Organization
Regulation Of Cellular Component Organization
Focal Adhesion
Positive Regulation Of Supramolecular Fiber Organization
Positive Regulation Of Organelle Organization
Positive Regulation Of Cytoskeleton Organization
Negative Regulation Of Supramolecular Fiber Organization
Lamellipodium
Ruffle
Actin Filament
Negative Regulation Of Cytoskeleton Organization
Negative Regulation Of Actin Filament Polymerization
Positive Regulation Of Cellular Component Organization
Positive Regulation Of Protein Localization
Cortical Actin Cytoskeleton
Positive Regulation Of Cellular Component Biogenesis
Actin Polymerization Or Depolymerization
Regulation Of Biological Quality
Anchoring Junction
Organelle Organization
Ruffle Membrane
Positive Regulation Of Protein-containing Complex Assembly
Cell Projection
Filopodium
Regulation Of Cell Shape
Muscle System Process
Negative Regulation Of Actin Filament Depolymerization
Regulation Of Protein Localization
Actin Filament
Actin Filament Organization
Actin Cytoskeleton
Focal Adhesion
Supramolecular Fiber Organization
Actin Filament Binding
Cortical Actin Cytoskeleton
Ruffle
Actin Binding
Actin Cytoskeleton Organization
S100 Protein Binding
Establishment Of Epithelial Cell Apical/basal Polarity
Actin Filament-based Process
Establishment Of Apical/basal Cell Polarity
Establishment Of Monopolar Cell Polarity
Establishment Or Maintenance Of Monopolar Cell Polarity
Polarized Epithelial Cell Differentiation
Establishment Of Epithelial Cell Polarity
Cell-cell Junction
Regulation Of Cellular Component Size
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Establishment Or Maintenance Of Apical/basal Cell Polarity
Sarcomere
Brush Border
Actin Filament Bundle Organization
Actin Filament Bundle Assembly
Regulation Of Plasma Membrane Raft Polarization
Phosphatidylinositol 3-kinase Catalytic Subunit Binding
Microvillus
Cytoskeletal Protein Binding
Cytosol
Cell Development
Plasma Membrane Bounded Cell Projection Organization
Filopodium
Stress Fiber
Structural Constituent Of Postsynapse
Positive Regulation Of Protein Processing In Phagocytic Vesicle
Establishment Of Cell Polarity
Terminal Web Assembly
Protein Phosphatase Binding
Cytoskeleton Organization
Muscle Cell Development
Cellular Developmental Process
Platelet Morphogenesis
Cell Projection Organization
Protein Localization To Cell Cortex
Intestinal D-glucose Absorption
Mitotic Actomyosin Contractile Ring Assembly Actin Filament Organization
Stereocilium Maintenance
Blood Microparticle
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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