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ACTA1 and TAGLN
Number of citations of the paper that reports this interaction (PubMedID
11053353
)
0
Data Source:
HPRD
(in vitro, in vivo)
ACTA1
TAGLN
Description
actin alpha 1, skeletal muscle
transgelin
Image
No pdb structure
GO Annotations
Cellular Component
Stress Fiber
Extracellular Space
Cytoplasm
Cytosol
Cytoskeleton
Striated Muscle Thin Filament
Actin Filament
Actin Cytoskeleton
Sarcomere
Lamellipodium
Filopodium
Cell Body
Extracellular Exosome
Blood Microparticle
Cytoplasm
Molecular Function
Nucleotide Binding
Structural Constituent Of Cytoskeleton
Protein Binding
ATP Binding
Hydrolase Activity
Myosin Binding
ADP Binding
Actin Binding
Protein Binding
Biological Process
Muscle Contraction
Positive Regulation Of Gene Expression
Skeletal Muscle Thin Filament Assembly
Skeletal Muscle Fiber Development
Mesenchyme Migration
Muscle Organ Development
Epithelial Cell Differentiation
Pathways
Striated Muscle Contraction
Regulation of CDH1 Function
Formation of the dystrophin-glycoprotein complex (DGC)
Formation of the dystrophin-glycoprotein complex (DGC)
Drugs
Latrunculin A
Sucrose
Ulapualide A
Kabiramide C
Jaspisamide A
Tmr
1-Methylhistidine
Phosphoaminophosphonic Acid-Adenylate Ester
Aplyronine A
Reidispongiolide A
Reidispongiolide C
Sphinxolide B
Latrunculin B
Artenimol
Diseases
Cap myopathy
Congenital fiber type disproportion (CFTD)
Nemaline myopathy
GWAS
Apolipoprotein B levels (
32203549
)
Breast cancer in childhood cancer survivors treated with more than 10 gray radiotherapy (
29059430
)
Medication use (calcium channel blockers) (
31015401
)
Refractive error (
32231278
)
Interacting Genes
115 interacting genes:
ABL1
ABRA
ACTR10
ACTR1B
ADSS2
AFAP1
AIF1
AJUBA
AMOT
ANXA2
BIN1
CCIN
CCT2
CCT4
CCT5
CFL1
CLIC5
CNN1
CORO2B
COTL1
CTNND1
CTTN
CYFIP1
CYTH1
DHX9
DLG1
DMD
DNASE1
DNMBP
DTNA
DUX4L9
EGFR
EPB41
EPB41L2
EPS8
FGD4
FHOD1
FSCN1
GAS2
GAS7
GC
GSN
HCLS1
HDAC4
HIP1R
HSPB2
HTRA2
IQGAP1
ITGA2
ITPKA
KIF23
KLHL20
LASP1
LINC00624
MACF1
MAP1A
MAPT
MIB2
MINPP1
MYL1
MYLK
MYO10
MYO6
MYO7A
MYO9B
NEXN
NR3C2
NRAP
PAK1
PARVA
PCYT1B
PFDN1
PFN1
PHACTR1
PLD1
PPP1R9B
PRKCA
PRKCD
PRKCE
RAC1
RNF167
RPS6KB1
S100A1
S100A4
SCIN
SMTN
SNCA
SORBS1
SPRR1A
SPTA1
SPTAN1
SPTBN2
TAGLN
TJP1
TLN1
TMSB4X
TMSB4Y
TNNI1
TNNI3
TNNI3K
TP53
TPM2
TPM3
TRIM55
TRIM63
TTN
UBC
USP25
USP6NL
UTRN
VASP
VAV1
VCL
VIL1
XIRP1
9 interacting genes:
ACD
ACTA1
GORASP2
PIK3CD
POT1
PRKCD
RNF14
TINF2
USP1
Entrez ID
58
6876
HPRD ID
00030
02891
Ensembl ID
ENSG00000143632
ENSG00000149591
Uniprot IDs
P68133
Q01995
Q5U0D2
PDB IDs
7RNS
7RNU
7RNV
9DUU
9DUV
Enriched GO Terms of Interacting Partners
?
Actin Binding
Actin Filament Binding
Cytoskeleton
Actin Cytoskeleton
Actin Filament-based Process
Cytoplasm
Actin Filament Organization
Regulation Of Supramolecular Fiber Organization
Regulation Of Actin Filament Organization
Actin Cytoskeleton Organization
Supramolecular Fiber Organization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Cytoskeleton Organization
Regulation Of Actin Filament Polymerization
Regulation Of Actin Filament Length
Regulation Of Cytoskeleton Organization
Regulation Of Actin Filament-based Process
Cytosol
Regulation Of Cellular Component Size
Regulation Of Protein-containing Complex Assembly
Cell Cortex
Cytoskeleton Organization
Regulation Of Organelle Organization
Regulation Of Cellular Component Organization
Focal Adhesion
Positive Regulation Of Supramolecular Fiber Organization
Positive Regulation Of Organelle Organization
Positive Regulation Of Cytoskeleton Organization
Negative Regulation Of Supramolecular Fiber Organization
Lamellipodium
Ruffle
Actin Filament
Negative Regulation Of Cytoskeleton Organization
Negative Regulation Of Actin Filament Polymerization
Positive Regulation Of Cellular Component Organization
Positive Regulation Of Protein Localization
Cortical Actin Cytoskeleton
Positive Regulation Of Cellular Component Biogenesis
Actin Polymerization Or Depolymerization
Regulation Of Biological Quality
Anchoring Junction
Organelle Organization
Ruffle Membrane
Positive Regulation Of Protein-containing Complex Assembly
Cell Projection
Filopodium
Regulation Of Cell Shape
Muscle System Process
Negative Regulation Of Actin Filament Depolymerization
Regulation Of Protein Localization
Telomere Assembly
Shelterin Complex
Nuclear Telomere Cap Complex
Telomere Capping
Regulation Of DNA Biosynthetic Process
Negative Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of DNA Metabolic Process
Telomeric DNA Binding
Negative Regulation Of DNA Biosynthetic Process
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance Via Telomere Lengthening
Telomerase Inhibitor Activity
Establishment Of Protein Localization To Telomere
Regulation Of DNA Metabolic Process
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Chromosome Organization
Protein Localization To Chromosome, Telomeric Region
Positive Regulation Of Macromolecule Metabolic Process
Telomere Maintenance
Positive Regulation Of Chromosome Organization
Regulation Of Telomere Maintenance
Positive Regulation Of Metabolic Process
Telomere Organization
Negative Regulation Of DNA Metabolic Process
Telomere Maintenance Via Telomerase
RNA-templated DNA Biosynthetic Process
Telomere Maintenance Via Telomere Lengthening
Chromosome, Telomeric Region
Positive Regulation Of Organelle Organization
Positive Regulation Of DNA Biosynthetic Process
Granulocyte Macrophage Colony-stimulating Factor Receptor Binding
Positive Regulation Of Phospholipid Scramblase Activity
Positive Regulation Of Glucosylceramide Catabolic Process
Positive Regulation Of Error-prone Translesion Synthesis
Positive Regulation Of DNA Strand Elongation
Regulation Of Chromosome Organization
Positive Regulation Of Telomeric D-loop Disassembly
G-rich Single-stranded DNA Binding
Positive Regulation Of Biosynthetic Process
Regulation Of Organelle Organization
Regulation Of Macromolecule Biosynthetic Process
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Negative Regulation Of Cellular Component Organization
Cell Surface Receptor Signaling Pathway Via STAT
Positive Regulation Of Sphingomyelin Catabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
DNA Metabolic Process
Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
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