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CYTH1 and PRKCD
Number of citations of the paper that reports this interaction (PMID
11438522
)
7
Data Source:
HPRD
(in vitro, in vivo)
CYTH1
PRKCD
Gene Name
cytohesin 1
protein kinase C, delta
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Trans-Golgi Network
Cytosol
Plasma Membrane
Tight Junction
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Endoplasmic Reticulum
Cytosol
Plasma Membrane
Cell-cell Junction
Nuclear Matrix
Perinuclear Region Of Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
ARF Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Lipid Binding
Protein Serine/threonine Kinase Activity
Protein Kinase C Activity
Calcium-independent Protein Kinase C Activity
Non-membrane Spanning Protein Tyrosine Kinase Activity
Protein Binding
ATP Binding
Enzyme Activator Activity
Enzyme Binding
Insulin Receptor Substrate Binding
Metal Ion Binding
Biological Process
Vesicle-mediated Transport
Regulation Of Cell Adhesion
Regulation Of ARF Protein Signal Transduction
Positive Regulation Of GTPase Activity
Establishment Of Epithelial Cell Polarity
Protein Phosphorylation
Apoptotic Process
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Cell Cycle
Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Activation Of Phospholipase C Activity
Blood Coagulation
Fibroblast Growth Factor Receptor Signaling Pathway
Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress
Gene Expression
Regulation Of Receptor Activity
Immunoglobulin Mediated Immune Response
Peptidyl-threonine Phosphorylation
Peptidyl-tyrosine Phosphorylation
Cytokine-mediated Signaling Pathway
Termination Of Signal Transduction
Platelet Activation
Negative Regulation Of Actin Filament Polymerization
Negative Regulation Of Protein Binding
Interleukin-10 Production
Interleukin-12 Production
Positive Regulation Of Superoxide Anion Generation
Negative Regulation Of Glial Cell Apoptotic Process
Positive Regulation Of Protein Dephosphorylation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
B Cell Proliferation
Neutrophil Activation
Defense Response To Bacterium
Negative Regulation Of MAP Kinase Activity
Innate Immune Response
Negative Regulation Of Insulin Receptor Signaling Pathway
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Negative Regulation Of Inflammatory Response
Negative Regulation Of Peptidyl-tyrosine Phosphorylation
Protein Stabilization
Negative Regulation Of Filopodium Assembly
Interferon-gamma-mediated Signaling Pathway
Negative Regulation Of Platelet Aggregation
Cellular Senescence
Positive Regulation Of Phospholipid Scramblase Activity
Positive Regulation Of Ceramide Biosynthetic Process
Positive Regulation Of Glucosylceramide Catabolic Process
Positive Regulation Of Sphingomyelin Catabolic Process
Positive Regulation Of Response To DNA Damage Stimulus
Positive Regulation Of Apoptotic Signaling Pathway
Pathways
Ca-dependent events
Signaling by GPCR
CaM pathway
Phospholipase C-mediated cascade
Signaling by FGFR in disease
Signaling by EGFRvIII in Cancer
PLCG1 events in ERBB2 signaling
Effects of PIP2 hydrolysis
Interferon gamma signaling
DAP12 signaling
Gastrin-CREB signalling pathway via PKC and MAPK
G alpha (z) signalling events
Role of phospholipids in phagocytosis
Fcgamma receptor (FCGR) dependent phagocytosis
Signaling by PDGF
Calmodulin induced events
Regulation of mRNA stability by proteins that bind AU-rich elements
Apoptotic cleavage of cellular proteins
DAP12 interactions
Opioid Signalling
EGFR interacts with phospholipase C-gamma
Signaling by ERBB2
G alpha (q) signalling events
Signaling by EGFR
GPCR downstream signaling
Signaling by VEGF
Calmodulin induced events
Downstream signal transduction
Signaling by EGFR in Cancer
Platelet activation, signaling and aggregation
G alpha (q) signalling events
HuR stabilizes mRNA
DAG and IP3 signaling
VEGFA-VEGFR2 Pathway
CaM pathway
VEGFR2 mediated cell proliferation
Downstream signaling of activated FGFR
Programmed Cell Death
Innate Immune System
Signalling by NGF
PLC beta mediated events
Interferon Signaling
Apoptotic execution phase
Cytokine Signaling in Immune system
Signaling by Ligand-Responsive EGFR Variants in Cancer
G-protein mediated events
NGF signalling via TRKA from the plasma membrane
Signaling by Overexpressed Wild-Type EGFR in Cancer
Signaling by FGFR
PLC-gamma1 signalling
Drugs
Diseases
GWAS
Bipolar disorder (
21926972
)
Ulcerative colitis (
23128233
)
Ventricular conduction (
21076409
)
Protein-Protein Interactions
12 interactors:
ACTA1
ARF1
ARF6
ARFRP1
ARR3
CYTIP
GNAQ
IPCEF1
ITGB2
ITSN1
PRKCD
TRIM23
118 interactors:
ACTA1
ACTA2
ACTB
ADAM9
ADCY7
ADD1
ADD2
ADRA2A
ADRB2
ADRBK1
AFAP1
AKT3
APP
ART3
BDKRB2
C1QBP
CD34
CDCP1
CHAT
CNP
CREBBP
CYTH1
DAB2
DYNC1H1
EEF1A1
EGFR
EIF2S1
ELAVL1
EP300
ESRRA
FLI1
FSCN1
FYN
GABRA1
GAP43
GNA12
GNA13
GNAZ
GNB2L1
GRM5
GSK3A
HABP4
HDAC5
HIST1H1A
HIST1H1B
HNRNPK
HSP90AA1
HSPA4
IGF1R
IKBKB
IL6ST
INSR
IRS1
ITGA6
ITGB2
ITGB4
ITGB7
ITPR1
KCNJ1
KCNJ4
KLF5
LCK
LMNB1
LMNB2
LYN
MACF1
MAPK1
MAPK3
MAPT
MBP
MEP1B
MS4A2
MUC1
NCF1
NCF4
NFE2L2
NUMB
OPRD1
PAK1
PDP1
PDP2
PDPK1
PEBP1
PIK3CA
PIK3CB
PLCB1
PLD2
PLSCR1
PLSCR3
PPARA
PPM1A
PPP1CA
PPP2CA
PPP2R5C
PRKCZ
PRKDC
PTK2B
PTPN22
PTPN6
PTPRA
RAC1
RAF1
RASGRP3
RIPK4
RUNX2
SDC4
SHC1
SRC
STAT1
STAT3
TAGLN
TIAM1
TNFRSF1A
VCP
VHL
YWHAB
YWHAG
YWHAZ
Entrez ID
9267
5580
HPRD ID
01630
01501
Ensembl ID
ENSG00000108669
ENSG00000163932
Uniprot IDs
Q15438
Q05655
PDB IDs
1BC9
4A4P
1YRK
2YUU
Enriched GO Terms of Interacting Partners
?
Small GTPase Mediated Signal Transduction
Vesicle-mediated Transport
Response To Stimulus
Cellular Response To Stimulus
Signal Transduction
Intracellular Signal Transduction
Signaling
Regulation Of Filopodium Assembly
Regulation Of Phosphorylation
Cell Communication
Activation Of Phospholipase C Activity
Positive Regulation Of Phospholipase C Activity
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Phospholipid Scramblase Activity
Positive Regulation Of Glucosylceramide Catabolic Process
Positive Regulation Of Sphingomyelin Catabolic Process
Positive Regulation Of Phospholipase Activity
Regulation Of Actin Cytoskeleton Organization
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Regulation Of Phospholipase Activity
Post-Golgi Vesicle-mediated Transport
Positive Regulation Of Lipase Activity
Regulation Of Actin Filament-based Process
Protein Stabilization
Positive Regulation Of Phospholipid Catabolic Process
Skeletal Muscle Fiber Adaptation
Apoptotic Process
Blood Coagulation
Hemostasis
Programmed Cell Death
Lymphocyte Proliferation
Cell Death
Mononuclear Cell Proliferation
Death
Regulation Of Protein Phosphorylation
Interleukin-10 Production
Regulation Of Cell Projection Assembly
Leukocyte Proliferation
Regulation Of Cytoskeleton Organization
Negative Regulation Of Filopodium Assembly
Regulation Of Protein Stability
Interleukin-12 Production
Regulation Of Reactive Oxygen Species Metabolic Process
Regulation Of Body Fluid Levels
Positive Regulation Of Ceramide Biosynthetic Process
Wound Healing
Skeletal Muscle Thin Filament Assembly
Regulation Of Actin Filament Polymerization
Embryonic Morphogenesis
Endocytosis
Signaling
Cell Communication
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Response To Organic Substance
Response To Organic Substance
Positive Regulation Of Metabolic Process
Signal Transduction
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Cellular Response To Peptide
Cellular Response To Stimulus
Cellular Response To Peptide Hormone Stimulus
Defense Response
Response To Stress
Cellular Response To Organonitrogen Compound
Response To Stimulus
Platelet Activation
Cellular Response To Hormone Stimulus
Regulation Of Signal Transduction
Immune System Process
Positive Regulation Of Phosphorylation
Regulation Of Protein Phosphorylation
Response To Peptide
Response To Hormone
Regulation Of Phosphorylation
Cellular Response To Growth Factor Stimulus
Regulation Of Phosphorus Metabolic Process
Innate Immune Response
Regulation Of Signaling
Response To Peptide Hormone
Response To Wounding
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Response To Growth Factor
Wound Healing
Cell Activation
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Kinase Activity
Hemostasis
Positive Regulation Of Cellular Protein Metabolic Process
Multicellular Organismal Development
Positive Regulation Of Protein Modification Process
Anatomical Structure Development
Positive Regulation Of Protein Phosphorylation
Cellular Response To Insulin Stimulus
Regulation Of Protein Metabolic Process
Regulation Of Kinase Activity
Fc Receptor Signaling Pathway
Immune Response
Response To Insulin
Tagcloud
?
alkenes
azotic
constructions
gnai1
gnao1
heterocycle
hm
hms
htr1b
htr2a
htr2b
htr4
htr6
htr7
kpnb1
pharmacopeia
prkaca
prkca
prkcb
prkce
prkcg
prkd1
propertied
pubchem
rock2
rps6ka1
rps6ka3
tlr8
tradition
Tagcloud (Difference)
?
alkenes
azotic
constructions
gnai1
gnao1
heterocycle
hm
hms
htr1b
htr2a
htr2b
htr4
htr6
htr7
kpnb1
pharmacopeia
prkaca
prkca
prkcb
prkce
prkcg
prkd1
propertied
pubchem
rock2
rps6ka1
rps6ka3
tlr8
tradition
Tagcloud (Intersection)
?