CYTH1

Gene Name		cytohesin 1
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Gene Ontology Annotations	Cellular Component	Cytoplasm Trans-Golgi Network Cytosol Plasma Membrane Tight Junction Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding
	Biological Process	Vesicle-mediated Transport Regulation Of Cell Adhesion Regulation Of ARF Protein Signal Transduction Positive Regulation Of GTPase Activity Establishment Of Epithelial Cell Polarity
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		12 interactors: ACTA1 ARF1 ARF6 ARFRP1 ARR3 CYTIP GNAQ IPCEF1 ITGB2 ITSN1 PRKCD TRIM23
Entrez ID		9267
HPRD ID		01630
Ensembl ID		ENSG00000108669
Uniprot IDs		Q15438
PDB IDs		1BC9 4A4P
Enriched GO Terms of Interacting Partners?		Small GTPase Mediated Signal Transduction Vesicle-mediated Transport Response To Stimulus Cellular Response To Stimulus Signal Transduction Intracellular Signal Transduction Signaling Regulation Of Filopodium Assembly Regulation Of Phosphorylation Cell Communication Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Positive Regulation Of Phospholipase Activity Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Phospholipase Activity Post-Golgi Vesicle-mediated Transport Positive Regulation Of Lipase Activity Regulation Of Actin Filament-based Process Protein Stabilization Positive Regulation Of Phospholipid Catabolic Process Skeletal Muscle Fiber Adaptation Apoptotic Process Blood Coagulation Hemostasis Programmed Cell Death Lymphocyte Proliferation Cell Death Mononuclear Cell Proliferation Death Regulation Of Protein Phosphorylation Interleukin-10 Production Regulation Of Cell Projection Assembly Leukocyte Proliferation Regulation Of Cytoskeleton Organization Negative Regulation Of Filopodium Assembly Regulation Of Protein Stability Interleukin-12 Production Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Body Fluid Levels Positive Regulation Of Ceramide Biosynthetic Process Wound Healing Skeletal Muscle Thin Filament Assembly Regulation Of Actin Filament Polymerization Embryonic Morphogenesis Endocytosis
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