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PRMT6 and SMARCD1
Number of citations of the paper that reports this interaction (PMID
23455924
)
3
Data Source:
BioGRID
(two hybrid)
PRMT6
SMARCD1
Gene Name
protein arginine methyltransferase 6
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
SWI/SNF Complex
NpBAF Complex
NBAF Complex
Molecular Function
Protein Binding
Protein-arginine Omega-N Monomethyltransferase Activity
Protein-arginine Omega-N Asymmetric Methyltransferase Activity
Histone Methyltransferase Activity
Histone Binding
Histone Methyltransferase Activity (H4-R3 Specific)
Histone Methyltransferase Activity (H3-R2 Specific)
Histone Methyltransferase Activity (H2A-R3 Specific)
Transcription Coactivator Activity
Protein Binding
Protein Complex Scaffold
Biological Process
Base-excision Repair
Chromatin Organization
Transcription, DNA-templated
Viral Process
Histone Methylation
Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine
Histone H3-R2 Methylation
Histone H4-R3 Methylation
Negative Regulation Of Transcription, DNA-templated
Nucleosome Disassembly
Chromatin Remodeling
Regulation Of Transcription From RNA Polymerase II Promoter
Nervous System Development
Chromatin-mediated Maintenance Of Transcription
Pathways
Chromatin modifying enzymes
Chromatin organization
RMTs methylate histone arginines
Chromatin modifying enzymes
Chromatin organization
RMTs methylate histone arginines
Drugs
Diseases
GWAS
Intelligence (
22449649
)
Non-obstructive azoospermia (
22197933
)
Obesity (early onset extreme) (
23563609
)
Sex hormone-binding globulin levels (
22829776
)
Protein-Protein Interactions
91 interactors:
AK8
AP1G2
ASB3
AUNIP
BCAT1
BLZF1
BMP3
C17orf82
C8orf74
CDCA4
CETN2
DCAF16
DNAJA3
DNALI1
DXO
FBL
FIP1L1
FKBP7
FYCO1
FYN
GBE1
GRHL3
GSTCD
GTPBP2
H3F3C
HESX1
HIST1H4F
HIST2H2AA3
HIST2H2BE
HIST2H3A
HIST2H3C
HIST4H4
HMGA1
HMGA2
HNRNPH2
HOXA1
HOXA5
HOXC4
ID2
KIAA0408
KIF9
KLHL20
LDHAL6B
LENG8
LOXL4
MALT1
MED28
MLC1
MNDA
MRPL38
MTF2
NEFL
NOSTRIN
NR1D2
OAS1
OPA3
PABPC1
PCGF5
PELO
PEX7
PIAS1
PSMD11
PYCRL
PYGO1
RAC1
RAD17
RASSF2
SERGEF
SLU7
SMAD9
SMARCD1
SNF8
SPATA22
SPIN1
SPSB1
SRGAP3
SSX2IP
STARD10
SUV39H1
TDO2
TEX35
THEMIS
TMED5
TRIB2
TSC1
UBXN10
WBSCR27
WDFY3
ZNF436
ZNF557
ZSCAN9
44 interactors:
ANP32B
APOA5
AR
C4BPA
CALCOCO2
CCDC85B
CDC5L
CDX2
CORO1A
DPF3
EGFL7
ESR1
FEZ1
FOS
GATA1
GCC1
HNRNPC
HSPB1
IGKC
JUN
KDM1A
KLF1
KRT15
KRT18
LDOC1
MED4
NME1
NONO
NR1H4
NR3C1
NUCB2
PAICS
PCBD1
PGR
PRDX1
PRMT6
RIF1
RPS29
SUV420H1
TNIP2
TP53
USHBP1
VPS37B
YWHAG
Entrez ID
55170
6602
HPRD ID
10505
03438
Ensembl ID
ENSG00000198890
ENSG00000066117
Uniprot IDs
Q96LA8
Q96GM5
PDB IDs
4HC4
Enriched GO Terms of Interacting Partners
?
Chromatin Silencing At RDNA
Heterocycle Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Aromatic Compound Metabolic Process
DNA Methylation On Cytosine
Chromatin Silencing
Gene Expression
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Gene Expression, Epigenetic
Gene Silencing
Negative Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Metabolic Process
Regulation Of Gene Expression
Regulation Of RNA Metabolic Process
RNA Metabolic Process
Cell Cycle
Cellular Metabolic Process
Organelle Organization
Oncogene-induced Cell Senescence
Chromatin Assembly Or Disassembly
Negative Regulation Of Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of RNA Biosynthetic Process
Cellular Process
Senescence-associated Heterochromatin Focus Assembly
DNA Methylation
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Cellular Senescence
Histone H4-K20 Demethylation
Transcription, DNA-templated
Cochlea Morphogenesis
Chromatin Assembly
Embryonic Organ Morphogenesis
Cellular Macromolecule Biosynthetic Process
Cell Aging
RNA Biosynthetic Process
Nucleosome Organization
Positive Regulation Of Macromolecule Biosynthetic Process
Cellular Senescence
Chromatin Organization
Macromolecule Biosynthetic Process
Chromosome Organization
Negative Regulation Of Megakaryocyte Differentiation
RNA Biosynthetic Process
Gene Expression
Transcription, DNA-templated
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Macromolecule Biosynthetic Process
Biosynthetic Process
Regulation Of Apoptotic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Regulation Of Cell Death
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Gene Expression
Chromatin Organization
Regulation Of Gene Expression
Cellular Response To Organic Substance
Response To Organic Substance
Developmental Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Positive Regulation Of Cellular Metabolic Process
Regulation Of RNA Biosynthetic Process
Regulation Of Metabolic Process
Intracellular Steroid Hormone Receptor Signaling Pathway
Regulation Of RNA Metabolic Process
Anatomical Structure Development
Transcription From RNA Polymerase II Promoter
System Development
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Transcription Initiation From RNA Polymerase II Promoter
Steroid Hormone Mediated Signaling Pathway
Negative Regulation Of Cell Death
Chromosome Organization
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Nitrogen Compound Metabolic Process
Intracellular Receptor Signaling Pathway
Positive Regulation Of Metabolic Process
Multicellular Organismal Development
DNA-templated Transcription, Initiation
Hormone-mediated Signaling Pathway
Regulation Of Cell Proliferation
Cellular Response To Hormone Stimulus
Regulation Of Cellular Process
Chromatin Modification
Tagcloud
?
bbrd
brucei
clade
clades
connects
dart
dihydrolipoamide
exemplified
fmr
homologues
methyltransferases
outgroup
paralogue
phylogeny
prmt1
prmt2
prmt3
prmt4
prmt5
prmt7
prmt8
prmt9
prmts
reconstructing
resolve
tbprmts
tedious
trypanosoma
uncharacterized
Tagcloud (Difference)
?
bbrd
brucei
clade
clades
connects
dart
dihydrolipoamide
exemplified
fmr
homologues
methyltransferases
outgroup
paralogue
phylogeny
prmt1
prmt2
prmt3
prmt4
prmt5
prmt7
prmt8
prmt9
prmts
reconstructing
resolve
tbprmts
tedious
trypanosoma
uncharacterized
Tagcloud (Intersection)
?