PRMT6 and KIF9

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid, two hybrid)

		PRMT6	KIF9
Gene Name		protein arginine methyltransferase 6	kinesin family member 9
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Podosome Cytoplasm Kinesin Complex Microtubule Vesicle
	Molecular Function	Protein Binding Protein-arginine Omega-N Monomethyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity Histone Binding Histone Methyltransferase Activity (H4-R3 Specific) Histone Methyltransferase Activity (H3-R2 Specific) Histone Methyltransferase Activity (H2A-R3 Specific)	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity Protein Dimerization Activity
	Biological Process	Base-excision Repair Chromatin Organization Transcription, DNA-templated Viral Process Histone Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Histone H3-R2 Methylation Histone H4-R3 Methylation Negative Regulation Of Transcription, DNA-templated	Microtubule-based Movement Blood Coagulation Metabolic Process Extracellular Matrix Disassembly Regulation Of Podosome Assembly Organelle Disassembly
Pathways		Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines	Kinesins Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Intelligence ( 22449649) Non-obstructive azoospermia ( 22197933) Obesity (early onset extreme) ( 23563609) Sex hormone-binding globulin levels ( 22829776)
Protein-Protein Interactions		91 interactors: AK8 AP1G2 ASB3 AUNIP BCAT1 BLZF1 BMP3 C17orf82 C8orf74 CDCA4 CETN2 DCAF16 DNAJA3 DNALI1 DXO FBL FIP1L1 FKBP7 FYCO1 FYN GBE1 GRHL3 GSTCD GTPBP2 H3F3C HESX1 HIST1H4F HIST2H2AA3 HIST2H2BE HIST2H3A HIST2H3C HIST4H4 HMGA1 HMGA2 HNRNPH2 HOXA1 HOXA5 HOXC4 ID2 KIAA0408 KIF9 KLHL20 LDHAL6B LENG8 LOXL4 MALT1 MED28 MLC1 MNDA MRPL38 MTF2 NEFL NOSTRIN NR1D2 OAS1 OPA3 PABPC1 PCGF5 PELO PEX7 PIAS1 PSMD11 PYCRL PYGO1 RAC1 RAD17 RASSF2 SERGEF SLU7 SMAD9 SMARCD1 SNF8 SPATA22 SPIN1 SPSB1 SRGAP3 SSX2IP STARD10 SUV39H1 TDO2 TEX35 THEMIS TMED5 TRIB2 TSC1 UBXN10 WBSCR27 WDFY3 ZNF436 ZNF557 ZSCAN9	13 interactors: CARD9 EFHC2 IKZF1 JAKMIP2 KRTAP10-3 KRTAP10-9 LZTS2 PRMT6 ROPN1 SSX2IP TRIM27 TRIM37 ZBTB8A
Entrez ID		55170	64147
HPRD ID		10505	07444
Ensembl ID		ENSG00000198890	ENSG00000088727
Uniprot IDs		Q96LA8	A8K932 Q9HAQ2
PDB IDs		4HC4	3NWN
Enriched GO Terms of Interacting Partners?		Chromatin Silencing At RDNA Heterocycle Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Methylation On Cytosine Chromatin Silencing Gene Expression Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression, Epigenetic Gene Silencing Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process RNA Metabolic Process Cell Cycle Cellular Metabolic Process Organelle Organization Oncogene-induced Cell Senescence Chromatin Assembly Or Disassembly Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Cellular Process Senescence-associated Heterochromatin Focus Assembly DNA Methylation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Senescence Histone H4-K20 Demethylation Transcription, DNA-templated Cochlea Morphogenesis Chromatin Assembly Embryonic Organ Morphogenesis Cellular Macromolecule Biosynthetic Process Cell Aging RNA Biosynthetic Process Nucleosome Organization Positive Regulation Of Macromolecule Biosynthetic Process Cellular Senescence Chromatin Organization Macromolecule Biosynthetic Process Chromosome Organization Negative Regulation Of Megakaryocyte Differentiation	Organelle Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Neutrophil Differentiation Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Histone H3-R2 Methylation Negative Regulation Of Interleukin-2 Secretion Chromatin Modification Histone H2A-K119 Monoubiquitination Chromatin Organization Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Centriole Replication Negative Regulation Of Calcium Ion Import Intraciliary Transport Involved In Cilium Morphogenesis Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Component Assembly Positive Regulation Of NK T Cell Differentiation Interferon-gamma Secretion Positive Regulation Of Granulocyte Differentiation Negative Regulation Of Cellular Metabolic Process Spindle Midzone Assembly Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Chromosome Organization Regulation Of Centriole Replication Histone H2A Monoubiquitination Aggresome Assembly Regulation Of Cellular Process Response To Peptidoglycan Microtubule Severing Transcription, DNA-templated Histone H4-R3 Methylation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cytoskeleton Organization RNA Biosynthetic Process Negative Regulation Of Viral Release From Host Cell Histone H2A Ubiquitination Negative Regulation Of Centrosome Duplication Peptidyl-arginine N-methylation Lymph Node Development Peyer's Patch Development Regulation Of Transcription, DNA-templated Regulation Of Tumor Necrosis Factor Biosynthetic Process Response To Muramyl Dipeptide Interferon-gamma Production Negative Regulation Of Interleukin-2 Production Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process
Tagcloud ?		bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt1 prmt2 prmt3 prmt4 prmt5 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized
Tagcloud (Difference) ?		bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt1 prmt2 prmt3 prmt4 prmt5 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized
Tagcloud (Intersection) ?