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INPP5K and TK1
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
INPP5K
TK1
Gene Name
inositol polyphosphate-5-phosphatase K
thymidine kinase 1, soluble
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Ruffle
Nucleus
Cytoplasm
Endoplasmic Reticulum
Trans-Golgi Network
Cytosol
Plasma Membrane
Membrane
Ruffle Membrane
Neuron Projection
Perinuclear Region Of Cytoplasm
Cytosol
Molecular Function
Inositol-polyphosphate 5-phosphatase Activity
Vasopressin Receptor Activity
Protein Binding
Inositol Bisphosphate Phosphatase Activity
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity
Phosphatidylinositol Trisphosphate Phosphatase Activity
Phosphatidylinositol Phosphate 5-phosphatase Activity
Lipid Phosphatase Activity
Inositol Trisphosphate Phosphatase Activity
Inositol-1,4,5-trisphosphate 5-phosphatase Activity
Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity
Thymidine Kinase Activity
ATP Binding
Zinc Ion Binding
Nucleoside Kinase Activity
Identical Protein Binding
Biological Process
In Utero Embryonic Development
Negative Regulation Of Protein Phosphorylation
Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of Protein Kinase Activity
Phospholipid Metabolic Process
Phosphatidylinositol Biosynthetic Process
G-protein Coupled Receptor Signaling Pathway
Negative Regulation Of Peptidyl-threonine Phosphorylation
Negative Regulation Of Glucose Transport
Dephosphorylation
Actin Cytoskeleton Organization
Cellular Response To Insulin Stimulus
Cellular Response To Hormone Stimulus
Negative Regulation Of Peptidyl-serine Phosphorylation
Negative Regulation Of Dephosphorylation
Positive Regulation Of Urine Volume
Glucose Homeostasis
Negative Regulation Of MAP Kinase Activity
Negative Regulation By Host Of Viral Transcription
Small Molecule Metabolic Process
Negative Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Insulin Receptor Signaling Pathway
Inositol Phosphate Dephosphorylation
Phosphatidylinositol Dephosphorylation
Negative Regulation Of Stress Fiber Assembly
Negative Regulation Of Protein Kinase B Signaling
Negative Regulation Of Calcium Ion Transport
Cellular Response To CAMP
Cellular Response To Tumor Necrosis Factor
Cellular Response To Epidermal Growth Factor Stimulus
Protein Targeting To Plasma Membrane
Negative Regulation Of Protein Targeting To Membrane
Ruffle Assembly
Negative Regulation Of Glycogen (starch) Synthase Activity
Positive Regulation Of Renal Water Transport
Liver Development
Nucleobase-containing Compound Metabolic Process
Pyrimidine Nucleobase Metabolic Process
Deoxyribonucleoside Monophosphate Biosynthetic Process
Nucleotide Biosynthetic Process
Response To Toxic Substance
Skeletal Muscle Cell Proliferation
Phosphorylation
Response To Nutrient Levels
Pyrimidine Nucleoside Salvage
Small Molecule Metabolic Process
Thymidine Metabolic Process
Response To Copper Ion
Digestive Tract Development
Protein Homotetramerization
Response To Cortisol
Nucleobase-containing Small Molecule Metabolic Process
Fetal Process Involved In Parturition
DNA Biosynthetic Process
Pathways
Synthesis of PIPs at the plasma membrane
Metabolism of lipids and lipoproteins
Phospholipid metabolism
PI Metabolism
Pyrimidine salvage reactions
Pyrimidine metabolism
Metabolism of nucleotides
Drugs
Dithioerythritol
Thymidine-5\'-Triphosphate
Diseases
GWAS
Protein-Protein Interactions
15 interactors:
ANXA7
ARL6IP1
BDNF
CDKN1A
CPTP
FATE1
HMOX2
KRT31
MAD2L1BP
NCOR2
PFDN1
SMN1
TANK
TK1
TTR
159 interactors:
A1BG
A2M
AAMP
ABHD4
ACTB
ACTL6B
ACTR1B
ADAMTS10
ADD1
AGAP1
ALAS1
ALB
APLP1
APP
ARFGAP1
ASNA1
ATG16L2
ATP5B
ATP6V1A
ATXN3
BAG6
C14orf1
C19orf60
CARHSP1
CCDC115
CCDC90B
CDC20
CDK1
CDK4
CDKN1A
CENPB
CHGB
CLEC3B
COL11A2
COL4A2
COL4A5
COPS6
CPNE6
CPSF3L
CRIP2
CRMP1
CSAD
DACT1
DALRD3
DCAF13
DDAH2
DEAF1
DMPK
DOCK7
DRAP1
DUS2
DYNC1I1
EEF1A1
EIF3G
EIF4A2
EIF6
EXT2
EZH2
F13A1
FAF1
FAM20C
FBN3
FGB
FLAD1
FST
FZR1
GAPDH
GDF9
GDI1
GLB1
GPCPD1
HADHB
HERC3
HMGXB3
HSPBAP1
IER3IP1
IGHM
IMMT
INPP5K
ITSN1
JADE1
JMJD1C
KDM6B
KIF21B
KIF5A
KLHL23
KLHL5
KMT2B
LOC148413
LRIF1
MAGEA4
MAST2
MED31
METTL23
MKI67
MPP1
MPPED1
MRFAP1
MRPL37
MSH2
NEUROD2
NGFR
NKIRAS2
NMT2
NRBP1
ODC1
PAAF1
PDE4DIP
PKM
PLD3
PLXNA3
PPP4C
PROC
PSME1
PTPN4
PTPRK
QARS
RBBP4
RBM48
RPA1
RPL13
RPS2
RUVBL1
RXRA
SDF4
SEMA5B
SEPT6
SETDB1
SEZ6L2
SMC5
SNX1
SP110
SULT1A3
SUMO3
TAF1C
TCTEX1D2
THOC3
TIAM2
TLE1
TMSB4X
TP53
TRIM46
TRMT2A
TSC2
TTC38
TUBA1A
TUBB2A
TUBB3
TYK2
UNC119
UPF2
USP4
WDR18
WDR60
WDR73
WIZ
ZBTB16
ZNF431
ZXDC
Entrez ID
51763
7083
HPRD ID
08489
01771
Ensembl ID
ENSG00000132376
ENSG00000167900
Uniprot IDs
B7Z4V9
F5GXZ0
Q9BT40
P04183
PDB IDs
1W4R
1XBT
2ORV
2WVJ
Enriched GO Terms of Interacting Partners
?
Response To Organic Cyclic Compound
Response To Hyperoxia
Epithelium Development
Response To Abiotic Stimulus
Tube Development
Response To Anesthetic
Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter
Ceramide 1-phosphate Transport
Fetal Process Involved In Parturition
Response To Fluoxetine
Response To L-glutamate
Response To Metal Ion
Response To Light Stimulus
Response To Lipid
Skeletal Muscle Cell Proliferation
Response To Hormone
Taste Bud Development
Dendrite Extension
Heme Oxidation
Cellular Response To Norepinephrine Stimulus
Regulation Of Retinal Cell Programmed Cell Death
Response To Radiation
Tissue Development
Response To Extracellular Stimulus
Ceramide Transport
Response To Inorganic Substance
Response To Steroid Hormone
Anatomical Structure Development
Thyroid Hormone Transport
Intestinal Epithelial Cell Maturation
Axon Target Recognition
Digestive Tract Development
Response To Norepinephrine
Response To Ether
Response To Cortisol
Thymidine Metabolic Process
Epithelial Cell Differentiation
Digestive System Development
Response To Glucocorticoid
Mitotic Cell Cycle Checkpoint
Cellular Response To Growth Factor Stimulus
Response To Corticosteroid
Deoxyribonucleoside Monophosphate Biosynthetic Process
Negative Regulation Of Synaptic Transmission, GABAergic
Cellular Response To UV-B
Positive Regulation Of Long-term Neuronal Synaptic Plasticity
Heme Catabolic Process
Response To Growth Factor
Response To Toxic Substance
Cellular Metabolic Process
Regulation Of Protein Metabolic Process
Cellular Protein Metabolic Process
Developmental Process
Anatomical Structure Development
System Development
Regulation Of Cellular Protein Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Multicellular Organismal Development
Cellular Localization
Metabolic Process
Regulation Of Metabolic Process
Organelle Organization
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Cell Cycle Phase Transition
Protein Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Catabolic Process
RNA Metabolic Process
Negative Regulation Of Cell Cycle
Posttranscriptional Regulation Of Gene Expression
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Protein Catabolic Process
Negative Regulation Of Cellular Metabolic Process
Cell Differentiation
Platelet Degranulation
Gene Expression
Regulation Of Mitotic Cell Cycle
Regulation Of Cell Cycle Process
Negative Regulation Of Mitotic Cell Cycle
Cellular Process
Biosynthetic Process
Regulation Of Cell Cycle
Positive Regulation Of Metabolic Process
Positive Regulation Of Protein Metabolic Process
Cell Cycle Process
Mitotic Cell Cycle Process
Axon Guidance
Chromatin Organization
Viral Process
Programmed Cell Death
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Chromosome Organization
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Cellular Response To Organic Substance
Mitotic Cell Cycle
Cellular Response To Growth Factor Stimulus
Tagcloud
?
american
artiodactyla
assigned
block
blot
cattle
chr
conservative
conserved
cow
electrophoresis
erbb2
hybrid
hybridization
localization
localized
means
mink
nf1
pepa
pig
prkca
rara
representatives
sheep
southern
swine
synteny
umph2
Tagcloud (Difference)
?
american
artiodactyla
assigned
block
blot
cattle
chr
conservative
conserved
cow
electrophoresis
erbb2
hybrid
hybridization
localization
localized
means
mink
nf1
pepa
pig
prkca
rara
representatives
sheep
southern
swine
synteny
umph2
Tagcloud (Intersection)
?