INPP5K and ARL6IP1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		INPP5K	ARL6IP1
Gene Name		inositol polyphosphate-5-phosphatase K	ADP-ribosylation factor-like 6 interacting protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Nucleus Cytoplasm Endoplasmic Reticulum Trans-Golgi Network Cytosol Plasma Membrane Membrane Ruffle Membrane Neuron Projection Perinuclear Region Of Cytoplasm	Sec61 Translocon Complex Cytosol Membrane Integral Component Of Membrane
	Molecular Function	Inositol-polyphosphate 5-phosphatase Activity Vasopressin Receptor Activity Protein Binding Inositol Bisphosphate Phosphatase Activity Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity Phosphatidylinositol Trisphosphate Phosphatase Activity Phosphatidylinositol Phosphate 5-phosphatase Activity Lipid Phosphatase Activity Inositol Trisphosphate Phosphatase Activity Inositol-1,4,5-trisphosphate 5-phosphatase Activity Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity	Protein Binding
	Biological Process	In Utero Embryonic Development Negative Regulation Of Protein Phosphorylation Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Protein Kinase Activity Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Glucose Transport Dephosphorylation Actin Cytoskeleton Organization Cellular Response To Insulin Stimulus Cellular Response To Hormone Stimulus Negative Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Dephosphorylation Positive Regulation Of Urine Volume Glucose Homeostasis Negative Regulation Of MAP Kinase Activity Negative Regulation By Host Of Viral Transcription Small Molecule Metabolic Process Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Insulin Receptor Signaling Pathway Inositol Phosphate Dephosphorylation Phosphatidylinositol Dephosphorylation Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Calcium Ion Transport Cellular Response To CAMP Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Protein Targeting To Plasma Membrane Negative Regulation Of Protein Targeting To Membrane Ruffle Assembly Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Renal Water Transport	Cotranslational Protein Targeting To Membrane
Pathways		Synthesis of PIPs at the plasma membrane Metabolism of lipids and lipoproteins Phospholipid metabolism PI Metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: ANXA7 ARL6IP1 BDNF CDKN1A CPTP FATE1 HMOX2 KRT31 MAD2L1BP NCOR2 PFDN1 SMN1 TANK TK1 TTR	40 interactors: ACSF2 ARL4D ARL6 C12orf10 COL4A3BP DIABLO FAM134C FBXW7 FDFT1 FXR2 GAD2 GOLPH3 GORASP2 HGS HMGCL INPP5K MTERF3 NAPB NDRG4 NUDT3 PAM16 PBX3 RAB33A RTN4 SENP2 SHMT2 SNX1 SNX10 SNX11 SNX12 SNX15 SNX3 SNX4 SPG21 SUCLA2 TFAM TUFM WIPI2 ZFYVE21 ZNF391
Entrez ID		51763	23204
HPRD ID		08489	09641
Ensembl ID		ENSG00000132376	ENSG00000170540
Uniprot IDs		B7Z4V9 F5GXZ0 Q9BT40	B7Z6S5 F5GXP4 Q15041
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Organic Cyclic Compound Response To Hyperoxia Epithelium Development Response To Abiotic Stimulus Tube Development Response To Anesthetic Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Ceramide 1-phosphate Transport Fetal Process Involved In Parturition Response To Fluoxetine Response To L-glutamate Response To Metal Ion Response To Light Stimulus Response To Lipid Skeletal Muscle Cell Proliferation Response To Hormone Taste Bud Development Dendrite Extension Heme Oxidation Cellular Response To Norepinephrine Stimulus Regulation Of Retinal Cell Programmed Cell Death Response To Radiation Tissue Development Response To Extracellular Stimulus Ceramide Transport Response To Inorganic Substance Response To Steroid Hormone Anatomical Structure Development Thyroid Hormone Transport Intestinal Epithelial Cell Maturation Axon Target Recognition Digestive Tract Development Response To Norepinephrine Response To Ether Response To Cortisol Thymidine Metabolic Process Epithelial Cell Differentiation Digestive System Development Response To Glucocorticoid Mitotic Cell Cycle Checkpoint Cellular Response To Growth Factor Stimulus Response To Corticosteroid Deoxyribonucleoside Monophosphate Biosynthetic Process Negative Regulation Of Synaptic Transmission, GABAergic Cellular Response To UV-B Positive Regulation Of Long-term Neuronal Synaptic Plasticity Heme Catabolic Process Response To Growth Factor Response To Toxic Substance	Protein Transport Establishment Of Protein Localization Protein Localization Cellular Localization Vesicle Organization Establishment Of Localization In Cell Intracellular Transport Organelle Organization Cellular Protein Localization Intracellular Protein Transport Negative Regulation Of Early Endosome To Late Endosome Transport Mitochondrion Organization Regulation Of DNA Endoreduplication Succinate Metabolic Process Regulation Of Early Endosome To Late Endosome Transport Transport Protein Localization To Cilium Regulation Of Protein Catabolic Process Membrane Invagination Endomembrane System Organization Negative Regulation Of Intracellular Transport Cell Projection Assembly Protein Localization To Organelle Vesicle-mediated Transport Negative Regulation Of SREBP Signaling Pathway Succinyl-CoA Pathway Diphosphoinositol Polyphosphate Catabolic Process Posterior Compartment Specification Anterior Compartment Pattern Formation Positive Regulation Of Renal Water Transport Diadenosine Polyphosphate Catabolic Process Intralumenal Vesicle Formation Membrane Organization Localization Within Membrane Protein Localization To Membrane Endoplasmic Reticulum Organization Regulation Of Vesicle-mediated Transport Inositol Phosphate Metabolic Process Negative Regulation Of Protein Transport Lamellipodium Organization Alcohol Catabolic Process Glutamate Decarboxylation To Succinate Negative Regulation Of Triglyceride Biosynthetic Process ER To Golgi Ceramide Transport Uroporphyrinogen III Biosynthetic Process Cell Adhesion Molecule Production Intermembrane Transport Endosomal Transport Protein Targeting Biosynthetic Process
Tagcloud ?			1a 2b 3c 4c cisternae elaborate elucidated envelope er exogenously harboring homology interconnected localizes organelle potency reticulon reticulons shaped shaping sheet sheets suppress suppresses tmem33 transmembrane tubular tubulation tubules
Tagcloud (Difference) ?			1a 2b 3c 4c cisternae elaborate elucidated envelope er exogenously harboring homology interconnected localizes organelle potency reticulon reticulons shaped shaping sheet sheets suppress suppresses tmem33 transmembrane tubular tubulation tubules
Tagcloud (Intersection) ?