INPP5K and CPTP

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		INPP5K	CPTP
Gene Name		inositol polyphosphate-5-phosphatase K	ceramide-1-phosphate transfer protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Nucleus Cytoplasm Endoplasmic Reticulum Trans-Golgi Network Cytosol Plasma Membrane Membrane Ruffle Membrane Neuron Projection Perinuclear Region Of Cytoplasm	Nuclear Outer Membrane Golgi Apparatus Cytosol Plasma Membrane Endosome Membrane
	Molecular Function	Inositol-polyphosphate 5-phosphatase Activity Vasopressin Receptor Activity Protein Binding Inositol Bisphosphate Phosphatase Activity Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity Phosphatidylinositol Trisphosphate Phosphatase Activity Phosphatidylinositol Phosphate 5-phosphatase Activity Lipid Phosphatase Activity Inositol Trisphosphate Phosphatase Activity Inositol-1,4,5-trisphosphate 5-phosphatase Activity Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity	Phospholipid Binding Phospholipid Transporter Activity Glycolipid Binding Ceramide 1-phosphate Binding Ceramide 1-phosphate Transporter Activity
	Biological Process	In Utero Embryonic Development Negative Regulation Of Protein Phosphorylation Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Protein Kinase Activity Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Glucose Transport Dephosphorylation Actin Cytoskeleton Organization Cellular Response To Insulin Stimulus Cellular Response To Hormone Stimulus Negative Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Dephosphorylation Positive Regulation Of Urine Volume Glucose Homeostasis Negative Regulation Of MAP Kinase Activity Negative Regulation By Host Of Viral Transcription Small Molecule Metabolic Process Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Insulin Receptor Signaling Pathway Inositol Phosphate Dephosphorylation Phosphatidylinositol Dephosphorylation Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Calcium Ion Transport Cellular Response To CAMP Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Protein Targeting To Plasma Membrane Negative Regulation Of Protein Targeting To Membrane Ruffle Assembly Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Renal Water Transport	Glycolipid Transport Ceramide 1-phosphate Transport
Pathways		Synthesis of PIPs at the plasma membrane Metabolism of lipids and lipoproteins Phospholipid metabolism PI Metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: ANXA7 ARL6IP1 BDNF CDKN1A CPTP FATE1 HMOX2 KRT31 MAD2L1BP NCOR2 PFDN1 SMN1 TANK TK1 TTR	7 interactors: CD7 ECM1 INPP5K PHF13 SMAD3 TCEB1 ZNF451
Entrez ID		51763	80772
HPRD ID		08489	18878
Ensembl ID		ENSG00000132376	ENSG00000224051
Uniprot IDs		B7Z4V9 F5GXZ0 Q9BT40	Q5TA50 S4S694
PDB IDs			4K80 4K84 4K85 4K8N 4KBS 4KF6
Enriched GO Terms of Interacting Partners?		Response To Organic Cyclic Compound Response To Hyperoxia Epithelium Development Response To Abiotic Stimulus Tube Development Response To Anesthetic Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Ceramide 1-phosphate Transport Fetal Process Involved In Parturition Response To Fluoxetine Response To L-glutamate Response To Metal Ion Response To Light Stimulus Response To Lipid Skeletal Muscle Cell Proliferation Response To Hormone Taste Bud Development Dendrite Extension Heme Oxidation Cellular Response To Norepinephrine Stimulus Regulation Of Retinal Cell Programmed Cell Death Response To Radiation Tissue Development Response To Extracellular Stimulus Ceramide Transport Response To Inorganic Substance Response To Steroid Hormone Anatomical Structure Development Thyroid Hormone Transport Intestinal Epithelial Cell Maturation Axon Target Recognition Digestive Tract Development Response To Norepinephrine Response To Ether Response To Cortisol Thymidine Metabolic Process Epithelial Cell Differentiation Digestive System Development Response To Glucocorticoid Mitotic Cell Cycle Checkpoint Cellular Response To Growth Factor Stimulus Response To Corticosteroid Deoxyribonucleoside Monophosphate Biosynthetic Process Negative Regulation Of Synaptic Transmission, GABAergic Cellular Response To UV-B Positive Regulation Of Long-term Neuronal Synaptic Plasticity Heme Catabolic Process Response To Growth Factor Response To Toxic Substance	Regulation Of Stress Fiber Assembly Regulation Of Bone Mineralization Regulation Of Viral Transcription Negative Regulation Of Ossification Positive Regulation Of Transforming Growth Factor Beta3 Production Positive Regulation Of Renal Water Transport Regulation Of Dephosphorylation Negative Regulation Of Glycogen (starch) Synthase Activity Evasion Or Tolerance Of Host Defenses By Virus Regulation Of Viral Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Ossification Regulation Of Extracellular Matrix Assembly Negative Regulation Of Protein Metabolic Process Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Protein Targeting To Membrane Primary MiRNA Processing Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Negative Regulation Of Glycogen Biosynthetic Process Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Osteoblast Proliferation Regulation Of Glycogen (starch) Synthase Activity SMAD Protein Complex Assembly Regulation Of Intracellular Protein Transport Regulation Of Transforming Growth Factor Beta2 Production Transdifferentiation T Cell Aggregation T Cell Activation Ossification Lymphocyte Aggregation Negative Regulation Of Signal Transduction Regulation Of Transcription, DNA-templated Leukocyte Aggregation Regulation Of Epithelial Cell Proliferation Positive Regulation Of Catenin Import Into Nucleus Regulation Of Nucleic Acid-templated Transcription Response To Hypoxia Regulation Of RNA Biosynthetic Process Negative Regulation By Host Of Viral Transcription Positive Regulation Of Alkaline Phosphatase Activity Negative Regulation Of Stress Fiber Assembly Regulation Of RNA Metabolic Process Inositol Phosphate Dephosphorylation Negative Regulation Of Protein Phosphorylation Leukocyte Cell-cell Adhesion Negative Regulation Of Signaling Positive Regulation Of Urine Volume Phosphorylated Carbohydrate Dephosphorylation
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